AU2020268885A1 - Markers for identifying and quantifying of nucleic acid sequence mutation, expression, splice variant, translocation, copy number, or methylation changes - Google Patents
Markers for identifying and quantifying of nucleic acid sequence mutation, expression, splice variant, translocation, copy number, or methylation changes Download PDFInfo
- Publication number
- AU2020268885A1 AU2020268885A1 AU2020268885A AU2020268885A AU2020268885A1 AU 2020268885 A1 AU2020268885 A1 AU 2020268885A1 AU 2020268885 A AU2020268885 A AU 2020268885A AU 2020268885 A AU2020268885 A AU 2020268885A AU 2020268885 A1 AU2020268885 A1 AU 2020268885A1
- Authority
- AU
- Australia
- Prior art keywords
- polymerase chain
- chain reaction
- nucleic acid
- sequence
- oligonucleotide primer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962843032P | 2019-05-03 | 2019-05-03 | |
| US62/843,032 | 2019-05-03 | ||
| PCT/US2020/031044 WO2020227100A1 (en) | 2019-05-03 | 2020-05-01 | Markers for identifying and quantifying of nucleic acid sequence mutation, expression, splice variant, translocation, copy number, or methylation changes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2020268885A1 true AU2020268885A1 (en) | 2021-12-02 |
Family
ID=73050598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020268885A Pending AU2020268885A1 (en) | 2019-05-03 | 2020-05-01 | Markers for identifying and quantifying of nucleic acid sequence mutation, expression, splice variant, translocation, copy number, or methylation changes |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220243263A1 (enExample) |
| EP (1) | EP3963095A4 (enExample) |
| JP (2) | JP2022530920A (enExample) |
| CN (1) | CN115244188A (enExample) |
| AU (1) | AU2020268885A1 (enExample) |
| BR (1) | BR112021022084A2 (enExample) |
| CA (1) | CA3135726A1 (enExample) |
| IL (1) | IL287804A (enExample) |
| SG (1) | SG11202112246UA (enExample) |
| WO (1) | WO2020227100A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3127329A1 (en) | 2019-01-24 | 2020-07-30 | Mayo Foundation For Medical Education And Research | Detecting endometrial cancer |
| US11702704B2 (en) | 2019-10-31 | 2023-07-18 | Mayo Foundation For Medical Education And Research | Detecting ovarian cancer |
| EP4267763B1 (en) * | 2020-12-24 | 2025-07-23 | Life Technologies Corporation | Compositions and methods for highly sensitive detection of target sequences in multiplex reactions |
| CA3211005A1 (en) * | 2021-03-05 | 2022-09-09 | Mayo Foundation For Medical Education And Research | Detecting cervical cancer |
| WO2022246000A1 (en) * | 2021-05-19 | 2022-11-24 | City Of Hope | Compositions and methods for determining dna methylation level in cancer |
| WO2023017001A1 (en) * | 2021-08-09 | 2023-02-16 | Epigenomics Ag | Improved methods for detecting colorectal cancer |
| CA3268032A1 (en) * | 2022-09-23 | 2024-03-28 | Flagship Pioneering Innovations Vi, Llc | NUCLEIC ACID AMPLIFICATION PROCESSES |
| WO2024154075A1 (en) * | 2023-01-18 | 2024-07-25 | Pixelgen Technologies Ab | Gap-fill ligation and primer extension reactions employing exonuclease-resistant or capture moiety means |
| AU2024263920A1 (en) * | 2023-04-24 | 2025-11-13 | Saga Diagnostics Ab | Detection of variants |
| WO2024259135A1 (en) | 2023-06-13 | 2024-12-19 | Intellia Therapeutics, Inc. | Assays for analysis of ribonucleic acid (rna) molecules |
| CN117305312B (zh) * | 2023-10-19 | 2024-08-20 | 西南大学 | 一个家蚕专一取食桑叶的决定基因Zfh3及其应用 |
| US20250223652A1 (en) * | 2024-01-05 | 2025-07-10 | Harbinger Health, Inc. | Tiered testing for high risk populations |
| CN118986863A (zh) * | 2024-10-18 | 2024-11-22 | 四川新泌学生物科技有限公司 | 一种外阴用外泌体凝胶及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE342378T1 (de) * | 1999-03-19 | 2006-11-15 | Cornell Res Foundation Inc | Verfahren das auf den gekoppelten reactionen der polymerase-kettenreaktion (pcr)-verdauung mit restriktionsenzymen und ligasenachweis basiert |
| EP2386654A1 (en) * | 2005-05-02 | 2011-11-16 | University of Southern California | DNA Methylation markers associated with the CpG island methylator phenotype (cimp) in human colorectal cancer |
| EP2129796B1 (en) * | 2007-02-21 | 2013-10-23 | Oslo Universitetssykehus HF | New markers for cancer |
| SG11201404899VA (en) * | 2012-02-14 | 2014-10-30 | Univ Cornell | Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions |
| SI4056712T1 (sl) * | 2012-09-20 | 2024-10-30 | The Chinese University Of Hong Kong | Neinvazivno določanje metiloma tumorja iz plazme |
| US10155991B2 (en) * | 2013-08-15 | 2018-12-18 | Xueliang James Xia | Biomarkers for use in colorectal cancer |
| PT3204520T (pt) * | 2014-10-08 | 2020-04-16 | Univ Cornell | Método de identificação e quantificação da expressão de ácidos nucleicos, variantes de splicing, translocação, número de cópias ou alterações de metilação |
| US10030272B2 (en) * | 2015-02-27 | 2018-07-24 | Mayo Foundation For Medical Education And Research | Detecting gastrointestinal neoplasms |
| US10829804B2 (en) * | 2015-03-23 | 2020-11-10 | The University Of North Carolina At Chapel Hill | Method for identification and enumeration of nucleic acid sequences, expression, splice variant, translocation, copy, or DNA methylation changes using combined nuclease, ligase, polymerase, terminal transferase, and sequencing reactions |
| ES2835866T5 (es) * | 2015-05-12 | 2024-12-02 | Hoffmann La Roche | Procedimientos terapéuticos y de diagnóstico para el cáncer |
| GB201511152D0 (en) * | 2015-06-24 | 2015-08-05 | Ucl Business Plc | Method of diagnosing bladder cancer |
| WO2018087129A1 (en) * | 2016-11-08 | 2018-05-17 | Region Nordjylland, Aalborg University Hospital | Colorectal cancer methylation markers |
| CA3076386A1 (en) * | 2017-09-29 | 2019-04-04 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Dna methylation biomarkers for cancer diagnosing |
-
2020
- 2020-05-01 JP JP2021565022A patent/JP2022530920A/ja active Pending
- 2020-05-01 WO PCT/US2020/031044 patent/WO2020227100A1/en not_active Ceased
- 2020-05-01 SG SG11202112246UA patent/SG11202112246UA/en unknown
- 2020-05-01 CN CN202080048135.9A patent/CN115244188A/zh active Pending
- 2020-05-01 US US17/608,537 patent/US20220243263A1/en active Pending
- 2020-05-01 AU AU2020268885A patent/AU2020268885A1/en active Pending
- 2020-05-01 BR BR112021022084A patent/BR112021022084A2/pt unknown
- 2020-05-01 CA CA3135726A patent/CA3135726A1/en active Pending
- 2020-05-01 EP EP20801778.0A patent/EP3963095A4/en active Pending
-
2021
- 2021-11-02 IL IL287804A patent/IL287804A/en unknown
-
2025
- 2025-06-02 JP JP2025091539A patent/JP2026002789A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL287804A (en) | 2022-01-01 |
| EP3963095A4 (en) | 2023-01-25 |
| WO2020227100A1 (en) | 2020-11-12 |
| SG11202112246UA (en) | 2021-12-30 |
| WO2020227100A8 (en) | 2022-01-13 |
| BR112021022084A2 (pt) | 2022-02-08 |
| EP3963095A1 (en) | 2022-03-09 |
| CA3135726A1 (en) | 2020-11-12 |
| JP2026002789A (ja) | 2026-01-08 |
| CN115244188A (zh) | 2022-10-25 |
| US20220243263A1 (en) | 2022-08-04 |
| JP2022530920A (ja) | 2022-07-04 |
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