AU2020244278A1 - A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing - Google Patents
A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing Download PDFInfo
- Publication number
- AU2020244278A1 AU2020244278A1 AU2020244278A AU2020244278A AU2020244278A1 AU 2020244278 A1 AU2020244278 A1 AU 2020244278A1 AU 2020244278 A AU2020244278 A AU 2020244278A AU 2020244278 A AU2020244278 A AU 2020244278A AU 2020244278 A1 AU2020244278 A1 AU 2020244278A1
- Authority
- AU
- Australia
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- diazaspiro
- pyrimidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962819162P | 2019-03-15 | 2019-03-15 | |
| US62/819,162 | 2019-03-15 | ||
| PCT/IB2020/000177 WO2020188352A1 (en) | 2019-03-15 | 2020-03-13 | A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2020244278A1 true AU2020244278A1 (en) | 2021-09-30 |
Family
ID=71092560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020244278A Abandoned AU2020244278A1 (en) | 2019-03-15 | 2020-03-13 | A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11576915B2 (https=) |
| EP (1) | EP3938043A1 (https=) |
| JP (1) | JP2022525202A (https=) |
| KR (1) | KR20210139293A (https=) |
| CN (1) | CN113784717A (https=) |
| AU (1) | AU2020244278A1 (https=) |
| CA (1) | CA3133589A1 (https=) |
| MX (1) | MX2021011224A (https=) |
| WO (1) | WO2020188352A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022507533A (ja) * | 2018-11-16 | 2022-01-18 | アルタバント・サイエンシズ・ゲーエムベーハー | 肺動脈性高血圧症および他疾患に関連する肺動脈性肺高血圧症の治療法 |
| US11607413B2 (en) * | 2019-01-30 | 2023-03-21 | Altavant Sciences Gmbh | Dosage regime and method for treating pulmonary arterial hypertension |
| US11576915B2 (en) | 2019-03-15 | 2023-02-14 | Altavant Sciences Gmbh | Method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing |
| WO2023062595A1 (en) * | 2021-10-14 | 2023-04-20 | Altavant Sciences Gmbh | Treatment of subjects having pulmonary arterial hypertension with rodatristat ethyl |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101815534A (zh) * | 2007-07-11 | 2010-08-25 | 莱西肯医药有限公司 | 用于治疗肺动脉高压以及相关疾病和病症的方法和组合物 |
| UA119247C2 (uk) | 2013-09-06 | 2019-05-27 | РОЙВЕНТ САЙЕНСИЗ ҐмбГ | Спіроциклічні сполуки як інгібітори триптофангідроксилази |
| US9399741B2 (en) | 2013-10-09 | 2016-07-26 | Uop Llc | Methods and apparatuses for desulfurizing hydrocarbon streams |
| KR20210102887A (ko) * | 2018-11-14 | 2021-08-20 | 알타반트 사이언시스 게엠베하 | 말초 세로토닌과 관련된 질병 또는 장애를 치료하기 위한 트립토판 하이드록실라제 1 (tph1)의 결정질 스피로사이클릭 화합물 억제제 |
| JP2022507533A (ja) * | 2018-11-16 | 2022-01-18 | アルタバント・サイエンシズ・ゲーエムベーハー | 肺動脈性高血圧症および他疾患に関連する肺動脈性肺高血圧症の治療法 |
| US20200188399A1 (en) | 2018-12-17 | 2020-06-18 | Altavant Sciences Gmbh | Method for treating interstitial lung disease |
| WO2020128608A1 (en) * | 2018-12-17 | 2020-06-25 | Altavant Sciences Gmbh | Compound for use in a method for treating sarcoidosis-associated pulmonary hypertension |
| US11607413B2 (en) | 2019-01-30 | 2023-03-21 | Altavant Sciences Gmbh | Dosage regime and method for treating pulmonary arterial hypertension |
| US11576915B2 (en) | 2019-03-15 | 2023-02-14 | Altavant Sciences Gmbh | Method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing |
-
2020
- 2020-03-13 US US16/818,236 patent/US11576915B2/en active Active
- 2020-03-13 AU AU2020244278A patent/AU2020244278A1/en not_active Abandoned
- 2020-03-13 CA CA3133589A patent/CA3133589A1/en active Pending
- 2020-03-13 CN CN202080033296.0A patent/CN113784717A/zh active Pending
- 2020-03-13 JP JP2021555469A patent/JP2022525202A/ja active Pending
- 2020-03-13 EP EP20732658.8A patent/EP3938043A1/en not_active Withdrawn
- 2020-03-13 MX MX2021011224A patent/MX2021011224A/es unknown
- 2020-03-13 WO PCT/IB2020/000177 patent/WO2020188352A1/en not_active Ceased
- 2020-03-13 KR KR1020217031156A patent/KR20210139293A/ko not_active Abandoned
-
2023
- 2023-01-04 US US18/149,992 patent/US20240024316A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US11576915B2 (en) | 2023-02-14 |
| US20200289510A1 (en) | 2020-09-17 |
| JP2022525202A (ja) | 2022-05-11 |
| KR20210139293A (ko) | 2021-11-22 |
| EP3938043A1 (en) | 2022-01-19 |
| US20240024316A1 (en) | 2024-01-25 |
| WO2020188352A1 (en) | 2020-09-24 |
| CN113784717A (zh) | 2021-12-10 |
| CA3133589A1 (en) | 2020-09-24 |
| MX2021011224A (es) | 2021-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |