AU2020240091A1 - Therapeutic methods and compositions for treating lymphoma using 6,8-bis-benzylthio-octanoic acid - Google Patents
Therapeutic methods and compositions for treating lymphoma using 6,8-bis-benzylthio-octanoic acid Download PDFInfo
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- AU2020240091A1 AU2020240091A1 AU2020240091A AU2020240091A AU2020240091A1 AU 2020240091 A1 AU2020240091 A1 AU 2020240091A1 AU 2020240091 A AU2020240091 A AU 2020240091A AU 2020240091 A AU2020240091 A AU 2020240091A AU 2020240091 A1 AU2020240091 A1 AU 2020240091A1
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- benzylthio
- bis
- lymphoma
- octanoic acid
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- 229940075930 picrate Drugs 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 description 1
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- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 description 1
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- NCDNCNXCDXHOMX-XGKFQTDJSA-N ritonavir Chemical compound N([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=1C=CC=CC=1)NC(=O)OCC=1SC=NC=1)CC=1C=CC=CC=1)C(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-XGKFQTDJSA-N 0.000 description 1
- 229960000311 ritonavir Drugs 0.000 description 1
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- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
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- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
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- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
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- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962820767P | 2019-03-19 | 2019-03-19 | |
| US62/820,767 | 2019-03-19 | ||
| PCT/US2020/023537 WO2020191144A1 (en) | 2019-03-19 | 2020-03-19 | Therapeutic methods and compositions for treating lymphoma using 6,8-bis-benzylthio-octanoic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2020240091A1 true AU2020240091A1 (en) | 2021-09-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020240091A Abandoned AU2020240091A1 (en) | 2019-03-19 | 2020-03-19 | Therapeutic methods and compositions for treating lymphoma using 6,8-bis-benzylthio-octanoic acid |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220151994A1 (https=) |
| EP (1) | EP3941453A4 (https=) |
| JP (1) | JP2022525779A (https=) |
| KR (1) | KR20220018959A (https=) |
| CN (1) | CN114040758A (https=) |
| AU (1) | AU2020240091A1 (https=) |
| BR (1) | BR112021018138A2 (https=) |
| CA (1) | CA3133101A1 (https=) |
| MX (1) | MX2021011250A (https=) |
| TW (1) | TW202102211A (https=) |
| WO (1) | WO2020191144A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3121645A1 (en) * | 2018-12-20 | 2020-06-25 | Rafael Pharmaceuticals, Inc. | Oral therapy using 6,8-bis-benzylthio-octanoic acid |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8263653B2 (en) * | 2007-04-18 | 2012-09-11 | Cornerstone Pharmaceuticals, Inc. | Pharmaceutical formulations containing lipoic acid derivatives |
-
2020
- 2020-03-19 MX MX2021011250A patent/MX2021011250A/es unknown
- 2020-03-19 CN CN202080022886.3A patent/CN114040758A/zh active Pending
- 2020-03-19 CA CA3133101A patent/CA3133101A1/en active Pending
- 2020-03-19 EP EP20774107.5A patent/EP3941453A4/en not_active Withdrawn
- 2020-03-19 KR KR1020217033115A patent/KR20220018959A/ko active Pending
- 2020-03-19 TW TW109109207A patent/TW202102211A/zh unknown
- 2020-03-19 WO PCT/US2020/023537 patent/WO2020191144A1/en not_active Ceased
- 2020-03-19 US US17/440,229 patent/US20220151994A1/en not_active Abandoned
- 2020-03-19 BR BR112021018138A patent/BR112021018138A2/pt unknown
- 2020-03-19 AU AU2020240091A patent/AU2020240091A1/en not_active Abandoned
- 2020-03-19 JP JP2021556419A patent/JP2022525779A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220018959A (ko) | 2022-02-15 |
| WO2020191144A1 (en) | 2020-09-24 |
| EP3941453A4 (en) | 2022-12-28 |
| CA3133101A1 (en) | 2020-09-24 |
| JP2022525779A (ja) | 2022-05-19 |
| BR112021018138A2 (pt) | 2021-11-16 |
| TW202102211A (zh) | 2021-01-16 |
| MX2021011250A (es) | 2022-02-11 |
| US20220151994A1 (en) | 2022-05-19 |
| EP3941453A1 (en) | 2022-01-26 |
| CN114040758A (zh) | 2022-02-11 |
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| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |