AU2019373948B2 - Apparatus to administer drugs to mechanically ventilated patients - Google Patents

Apparatus to administer drugs to mechanically ventilated patients Download PDF

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Publication number
AU2019373948B2
AU2019373948B2 AU2019373948A AU2019373948A AU2019373948B2 AU 2019373948 B2 AU2019373948 B2 AU 2019373948B2 AU 2019373948 A AU2019373948 A AU 2019373948A AU 2019373948 A AU2019373948 A AU 2019373948A AU 2019373948 B2 AU2019373948 B2 AU 2019373948B2
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AU
Australia
Prior art keywords
dry powder
powder inhaler
connector
duct
curved tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2019373948A
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English (en)
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AU2019373948A1 (en
Inventor
Ruben AGAZZI
Benedetta CAMPOLO
Nicolò DALLACASA
Edoardo DAVICO
Chantal Erika SPEZIALI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of AU2019373948A1 publication Critical patent/AU2019373948A1/en
Application granted granted Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816—Joints or connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0883—Circuit type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816—Joints or connectors
    • A61M16/0833—T- or Y-type connectors, e.g. Y-piece
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/107—Filters in a path in the inspiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16—Devices to humidify the respiration air
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/201—Controlled valves
    • A61M16/202—Controlled valves electrically actuated
    • A61M16/203—Proportional
    • A61M16/204—Proportional used for inhalation control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7536—General characteristics of the apparatus with filters allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2019373948A 2018-10-30 2019-10-22 Apparatus to administer drugs to mechanically ventilated patients Active AU2019373948B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18203344.9 2018-10-30
EP18203344 2018-10-30
PCT/EP2019/078668 WO2020088984A1 (en) 2018-10-30 2019-10-22 Apparatus to administer drugs to mechanically ventilated patients

Publications (2)

Publication Number Publication Date
AU2019373948A1 AU2019373948A1 (en) 2021-06-03
AU2019373948B2 true AU2019373948B2 (en) 2023-11-16

Family

ID=64048753

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019373948A Active AU2019373948B2 (en) 2018-10-30 2019-10-22 Apparatus to administer drugs to mechanically ventilated patients

Country Status (11)

Country Link
US (1) US12097329B2 (https=)
EP (1) EP3873574B1 (https=)
JP (1) JP7368065B2 (https=)
KR (1) KR102778714B1 (https=)
CN (1) CN112969490B (https=)
AU (1) AU2019373948B2 (https=)
CA (1) CA3116673A1 (https=)
ES (1) ES2969709T3 (https=)
MA (1) MA54045A (https=)
MX (1) MX2021004643A (https=)
WO (1) WO2020088984A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115006656A (zh) * 2022-05-18 2022-09-06 苏州易合医药有限公司 一种可连续提供肺部活性剂粉雾剂的给药装置
EP4374903A1 (en) * 2022-11-24 2024-05-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Administering an aerosol to a patient

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090025722A1 (en) * 2006-02-01 2009-01-29 Michael Pieper Adapter for inhalation appliances for treatment of artificially ventilated patients
DE102008050218A1 (de) * 2007-10-04 2009-07-16 Activaero Gmbh Systeme und Verfahren zur Applikation inhalierbarer Stoffe in eine Lunge
US20130319410A1 (en) * 2012-05-30 2013-12-05 The University Of Kansas Inhalation device, systems, and methods for administering powdered medicaments to mechanically ventilated subjects
WO2015085362A1 (en) * 2013-12-11 2015-06-18 De Motu Cordis Medicament apparatus and method

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5823179A (en) * 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
DE50015462D1 (de) 1999-04-07 2009-01-02 Event Medical Ltd Beatmungsgerät
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
EP1658872B2 (en) * 2002-07-31 2019-08-21 CHIESI FARMACEUTICI S.p.A. Powder inhaler
US20040173211A1 (en) * 2003-01-14 2004-09-09 Boehringer Ingelheim International Gmbh Powder inhaler
KR101226995B1 (ko) 2004-04-20 2013-01-28 노바르티스 아게 압력 보조식 호흡 장치용 에어로졸 전달 장치
DE102006006183A1 (de) * 2006-02-10 2007-08-16 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung für die Anwendung bei Frühgeborenen und Kleinkindern
DE102008022987A1 (de) * 2008-05-09 2009-11-12 Pari Pharma Gmbh Vernebler für Beatmungsmaschinen und Beatmungsmaschine mit einem solchen Vernebler
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
AR087841A1 (es) 2011-09-14 2014-04-23 Chiesi Farma Spa Derivados de tetrahidrotriazolopirimidina
EP2806931B1 (en) * 2012-01-23 2019-04-10 AEON Research and Technology, LLC Modular pulmonary treatment system
AU2013211656B2 (en) 2012-01-25 2017-07-13 Chiesi Farmaceutici S.P.A. Dry powder formulation comprising a corticosteroid and a beta-adrenergic for administration by inhalation
US11052202B2 (en) 2012-11-07 2021-07-06 Chiesi Farmaceutici S.P.A. Drug delivery device for the treatment of patients with respiratory diseases
NZ709153A (en) 2012-12-18 2019-01-25 Chiesi Farm Spa Pyrimidinone derivatives having human neutrophil elastase inhibitory activity
TWI672297B (zh) 2013-12-18 2019-09-21 義大利商吉斯藥品公司 作為磷脂肌醇－３－激酶抑制劑之異唏衍生物
PL3160555T3 (pl) 2014-06-30 2019-10-31 Chiesi Farm Spa Inhalator suchego proszku i jego mechanizm uruchamiany przez wdychanie
CA3177844A1 (en) * 2015-03-31 2016-10-06 Fisher & Paykel Healthcare Limited Apparatus for use in a respiratory support system
US11395896B2 (en) * 2015-08-13 2022-07-26 Atilla SEVINCLI Coaxial and double lumen breathing circuit systems having a lung pressure measurement port and closed system water trap which can be drained with an enjector
WO2018213834A1 (en) * 2017-05-19 2018-11-22 Pneuma Respiratory, Inc. Dry powder delivery device and methods of use
AU2018275561A1 (en) * 2017-05-31 2019-12-12 Virginia Commonwealth University Devices, systems, and methods for dry powder therapies

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090025722A1 (en) * 2006-02-01 2009-01-29 Michael Pieper Adapter for inhalation appliances for treatment of artificially ventilated patients
DE102008050218A1 (de) * 2007-10-04 2009-07-16 Activaero Gmbh Systeme und Verfahren zur Applikation inhalierbarer Stoffe in eine Lunge
US20130319410A1 (en) * 2012-05-30 2013-12-05 The University Of Kansas Inhalation device, systems, and methods for administering powdered medicaments to mechanically ventilated subjects
WO2015085362A1 (en) * 2013-12-11 2015-06-18 De Motu Cordis Medicament apparatus and method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BENNY FENG ET AL: "A Novel In-Line Delivery System to Administer Dry Powder Mannitol to Mechanically Ventilated Patients", DOI: 10.1089/jamp.2016.1320 *

Also Published As

Publication number Publication date
ES2969709T3 (es) 2024-05-22
BR112021007775A2 (pt) 2021-07-27
JP7368065B2 (ja) 2023-10-24
CA3116673A1 (en) 2020-05-07
CN112969490A (zh) 2021-06-15
EP3873574B1 (en) 2023-12-06
JP2022504924A (ja) 2022-01-13
KR102778714B1 (ko) 2025-03-10
WO2020088984A1 (en) 2020-05-07
US12097329B2 (en) 2024-09-24
CN112969490B (zh) 2024-07-12
EP3873574A1 (en) 2021-09-08
MA54045A (fr) 2021-09-08
MX2021004643A (es) 2021-05-28
KR20210086614A (ko) 2021-07-08
US20210370007A1 (en) 2021-12-02
AU2019373948A1 (en) 2021-06-03

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