AU2019360953A1 - Methods and compositions for treatment of glaucoma and related conditions - Google Patents

Methods and compositions for treatment of glaucoma and related conditions Download PDF

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Publication number
AU2019360953A1
AU2019360953A1 AU2019360953A AU2019360953A AU2019360953A1 AU 2019360953 A1 AU2019360953 A1 AU 2019360953A1 AU 2019360953 A AU2019360953 A AU 2019360953A AU 2019360953 A AU2019360953 A AU 2019360953A AU 2019360953 A1 AU2019360953 A1 AU 2019360953A1
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AU
Australia
Prior art keywords
patient
eye
dosage
alpha
phentolamine
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Abandoned
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AU2019360953A
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English (en)
Inventor
Konstantinos Charizanis
Alan R. Meyer
William H. PITLICK
Mina SOOCH
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Opus Genetics Inc
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Ocuphire Pharma Inc
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Publication of AU2019360953A1 publication Critical patent/AU2019360953A1/en
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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  • Oil, Petroleum & Natural Gas (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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AU2019360953A 2018-10-15 2019-10-15 Methods and compositions for treatment of glaucoma and related conditions Abandoned AU2019360953A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862745806P 2018-10-15 2018-10-15
US62/745,806 2018-10-15
US201862752088P 2018-10-29 2018-10-29
US62/752,088 2018-10-29
PCT/US2019/056324 WO2020081562A1 (en) 2018-10-15 2019-10-15 Methods and compositions for treatment of glaucoma and related conditions

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AU2019360953A1 true AU2019360953A1 (en) 2021-05-13

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US (1) US12161629B2 (https=)
EP (1) EP3866790A4 (https=)
JP (1) JP2022508715A (https=)
CN (1) CN113164451A (https=)
AU (1) AU2019360953A1 (https=)
WO (1) WO2020081562A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3116589A1 (en) 2018-10-26 2020-04-30 Ocuphire Pharma, Inc. Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders
WO2022034909A1 (ja) * 2020-08-13 2022-02-17 参天製薬株式会社 セペタプロストを含有する医薬製剤
CN117529316A (zh) * 2021-04-23 2024-02-06 奥库菲尔制药股份有限公司 用于治疗瞳孔散大、青光眼和其他眼部病症的方法和组合物
EP4408535A1 (en) * 2021-09-30 2024-08-07 Regeneron Pharmaceuticals, Inc. Treatment of glaucoma with rho guanine nucleotide exchange factor 12 (arhgef12) inhibitors
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