AU2019247034B2 - Antigenic respiratory syncytial virus polypeptides - Google Patents

Antigenic respiratory syncytial virus polypeptides

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Publication number
AU2019247034B2
AU2019247034B2 AU2019247034A AU2019247034A AU2019247034B2 AU 2019247034 B2 AU2019247034 B2 AU 2019247034B2 AU 2019247034 A AU2019247034 A AU 2019247034A AU 2019247034 A AU2019247034 A AU 2019247034A AU 2019247034 B2 AU2019247034 B2 AU 2019247034B2
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AU
Australia
Prior art keywords
rsv
polypeptide
ferritin
seq
antigenic
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Active
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AU2019247034A
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English (en)
Other versions
AU2019247034A1 (en
Inventor
Magnus BESEV
Pradeep Dhal
Ram DHARANIPRAGADA
Gary J. Nabel
Kurt Swanson
Chih-Jen Wei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of AU2019247034A1 publication Critical patent/AU2019247034A1/en
Application granted granted Critical
Publication of AU2019247034B2 publication Critical patent/AU2019247034B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2019247034A 2018-04-03 2019-04-02 Antigenic respiratory syncytial virus polypeptides Active AU2019247034B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862652199P 2018-04-03 2018-04-03
US62/652,199 2018-04-03
PCT/US2019/025387 WO2019195291A1 (en) 2018-04-03 2019-04-02 Antigenic respiratory syncytial virus polypeptides

Publications (2)

Publication Number Publication Date
AU2019247034A1 AU2019247034A1 (en) 2020-10-22
AU2019247034B2 true AU2019247034B2 (en) 2025-12-11

Family

ID=66182672

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019247034A Active AU2019247034B2 (en) 2018-04-03 2019-04-02 Antigenic respiratory syncytial virus polypeptides

Country Status (10)

Country Link
US (2) US12071454B2 (https=)
EP (1) EP3773704A1 (https=)
JP (2) JP7614841B2 (https=)
KR (1) KR20210018206A (https=)
CN (1) CN112512567A (https=)
AU (1) AU2019247034B2 (https=)
BR (1) BR112020019938A2 (https=)
CA (1) CA3095175A1 (https=)
MX (1) MX2020010199A (https=)
WO (1) WO2019195291A1 (https=)

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WO2019195314A2 (en) 2018-04-03 2019-10-10 Sanofi Antigenic epstein barr virus polypeptides
MX2024005462A (es) 2021-11-05 2024-05-22 Sanofi Sa Vacuna de arn del virus respiratorio sincitial.
WO2023201222A1 (en) * 2022-04-11 2023-10-19 Vanderbilt University Ferritin nanoparticles and methods of use thereof
WO2024041773A1 (en) * 2022-08-22 2024-02-29 Glaxosmithkline Biologicals Sa Rsv-f proteins
WO2024078597A1 (en) * 2022-10-13 2024-04-18 Rvac Medicines (Us) , Inc. Rsv f protein variants and uses thereof
KR20250099727A (ko) 2022-11-04 2025-07-02 사노피 파스퇴르 인크 호흡기 세포융합 바이러스 rna 백신접종
WO2024231565A1 (en) 2023-05-10 2024-11-14 Sanofi Combination respiratory mrna vaccines
WO2025026448A1 (zh) * 2023-08-03 2025-02-06 广州穗和生物技术有限公司 修饰的呼吸道合胞病毒f蛋白及其用途
WO2025092933A1 (zh) * 2023-10-31 2025-05-08 上海蓝鹊生物医药有限公司 一种rsv抗原、核酸、重组表达载体、药物组合物及其应用
CN117586359A (zh) * 2024-01-19 2024-02-23 北京安百胜生物科技有限公司 一种具有免疫原性的呼吸道合胞病毒（rsv）多肽
CN120099235A (zh) * 2025-05-09 2025-06-06 北京华诺泰生物医药科技有限公司 一种微生物发酵工艺的优化方法及装置

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Also Published As

Publication number Publication date
AU2019247034A1 (en) 2020-10-22
CN112512567A (zh) 2021-03-16
WO2019195291A1 (en) 2019-10-10
RU2020135568A (ru) 2022-05-06
BR112020019938A2 (pt) 2021-01-26
US12071454B2 (en) 2024-08-27
CA3095175A1 (en) 2019-10-10
KR20210018206A (ko) 2021-02-17
US20250059240A1 (en) 2025-02-20
MX2020010199A (es) 2021-01-08
JP2024170566A (ja) 2024-12-10
JP2021519597A (ja) 2021-08-12
JP7614841B2 (ja) 2025-01-16
EP3773704A1 (en) 2021-02-17
US20210017237A1 (en) 2021-01-21

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