AU2019224025B2 - Methods for prostate cancer detection and treatment - Google Patents
Methods for prostate cancer detection and treatment Download PDFInfo
- Publication number
- AU2019224025B2 AU2019224025B2 AU2019224025A AU2019224025A AU2019224025B2 AU 2019224025 B2 AU2019224025 B2 AU 2019224025B2 AU 2019224025 A AU2019224025 A AU 2019224025A AU 2019224025 A AU2019224025 A AU 2019224025A AU 2019224025 B2 AU2019224025 B2 AU 2019224025B2
- Authority
- AU
- Australia
- Prior art keywords
- tmprss2
- erg
- score
- subject
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Databases & Information Systems (AREA)
- Bioethics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Data Mining & Analysis (AREA)
- Artificial Intelligence (AREA)
- Epidemiology (AREA)
- Evolutionary Computation (AREA)
- Public Health (AREA)
- Software Systems (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2025238057A AU2025238057A1 (en) | 2018-02-22 | 2025-09-26 | Methods for prostate cancer detection and treatment |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862633675P | 2018-02-22 | 2018-02-22 | |
| US62/633,675 | 2018-02-22 | ||
| PCT/US2019/018878 WO2019165021A1 (en) | 2018-02-22 | 2019-02-21 | Methods for prostate cancer detection and treatment |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2025238057A Division AU2025238057A1 (en) | 2018-02-22 | 2025-09-26 | Methods for prostate cancer detection and treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2019224025A1 AU2019224025A1 (en) | 2020-09-10 |
| AU2019224025B2 true AU2019224025B2 (en) | 2025-06-26 |
Family
ID=65686083
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019224025A Active AU2019224025B2 (en) | 2018-02-22 | 2019-02-21 | Methods for prostate cancer detection and treatment |
| AU2025238057A Pending AU2025238057A1 (en) | 2018-02-22 | 2025-09-26 | Methods for prostate cancer detection and treatment |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2025238057A Pending AU2025238057A1 (en) | 2018-02-22 | 2025-09-26 | Methods for prostate cancer detection and treatment |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11410748B2 (https=) |
| EP (2) | EP3755816B1 (https=) |
| JP (2) | JP7662337B2 (https=) |
| KR (2) | KR102921718B1 (https=) |
| CN (2) | CN119932188A (https=) |
| AU (2) | AU2019224025B2 (https=) |
| BR (1) | BR112020016989A2 (https=) |
| CA (1) | CA3091647A1 (https=) |
| DK (1) | DK3755816T3 (https=) |
| ES (1) | ES3023842T3 (https=) |
| IL (1) | IL276748A (https=) |
| MX (2) | MX2020008702A (https=) |
| PL (1) | PL3755816T3 (https=) |
| SG (1) | SG11202007922XA (https=) |
| WO (1) | WO2019165021A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2022004372A (es) | 2019-10-10 | 2022-07-27 | Liquid Biopsy Res Llc | Composiciones, métodos y kits para la estabilización de muestras biológicas y de arn. |
| EP4100955A4 (en) * | 2020-02-06 | 2024-02-28 | Oncohost Ltd | MACHINE LEARNING PREDICTION OF THERAPEUTIC RESPONSE |
| CA3227993A1 (en) | 2021-08-11 | 2023-02-16 | OncoHost Ltd. | Predicting patient response |
| EP4602184A1 (en) * | 2022-10-12 | 2025-08-20 | Liquid Biopsy Research LLC | Methods for prostate cancer detection in saliva |
| GB2623570B (en) * | 2022-10-21 | 2025-07-23 | Wobble Genomics Ltd | Method and products for biomarker identification |
| KR102891032B1 (ko) * | 2022-12-29 | 2025-12-03 | 재단법인대구경북과학기술원 | 혈액 단구세포 전사체 생체표지자를 이용한 전이성 전립선암 진단용 바이오마커 및 이의 용도 |
| CN116908444B (zh) * | 2023-09-13 | 2023-12-19 | 中国医学科学院北京协和医院 | 血浆max自身抗体在晚期非小细胞肺癌pd-1单抗联合化疗治疗预后预测中的应用 |
| CN119964650B (zh) * | 2024-12-24 | 2025-09-30 | 深圳大学 | 一种基于集成学习的基因调控网络推断方法和系统 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015021158A1 (en) * | 2013-08-06 | 2015-02-12 | Exosome Diagnostics, Inc. | Urine biomarker cohorts, gene expression signatures, and methods of use thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009540852A (ja) * | 2006-07-03 | 2009-11-26 | エグゾニ・テラピューティック・ソシエテ・アノニム | 前立腺特異的な転写物ならびに前立腺癌の治療および診断におけるその使用 |
| US20100303795A1 (en) * | 2009-05-27 | 2010-12-02 | Soerensen Karina Dalsgaard | Marker of prostate cancer |
| MX338883B (es) * | 2010-07-27 | 2016-05-04 | Genomic Health Inc | Metodo para usar expresion de gen para determinar el pronostico de cancer de prostata. |
| US8725426B2 (en) | 2012-01-31 | 2014-05-13 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| CA2879557A1 (en) * | 2012-07-20 | 2014-01-23 | Diagnocure Inc. | Methods, kits and compositions for providing a clinical assessment of prostate cancer |
| EP2882869A4 (en) * | 2012-08-07 | 2016-04-20 | Jackson H M Found Military Med | PROSTATE CANCER GENE EXPRESSION PROFILE |
| US10431326B2 (en) * | 2012-11-20 | 2019-10-01 | Phadia Ab | Method for indicating a presence or non-presence of aggressive prostate cancer |
| SG10201907684PA (en) * | 2013-01-15 | 2019-10-30 | Aragon Pharmaceuticals Inc | Androgen receptor modulator and uses thereof |
| CN105209636A (zh) * | 2013-03-15 | 2015-12-30 | 麦塔马克基因股份有限公司 | 用于癌症预后的组合物和方法 |
| EP3800266A1 (en) * | 2013-06-13 | 2021-04-07 | University Of South Australia | Methods for detecting prostate cancer |
| EP3214444A1 (en) | 2016-03-04 | 2017-09-06 | AIT Austrian Institute of Technology GmbH | Prostate cancer diagnostic method and means |
-
2019
- 2019-02-21 EP EP19709298.4A patent/EP3755816B1/en active Active
- 2019-02-21 WO PCT/US2019/018878 patent/WO2019165021A1/en not_active Ceased
- 2019-02-21 KR KR1020207026864A patent/KR102921718B1/ko active Active
- 2019-02-21 ES ES19709298T patent/ES3023842T3/es active Active
- 2019-02-21 KR KR1020267002939A patent/KR20260018206A/ko active Pending
- 2019-02-21 MX MX2020008702A patent/MX2020008702A/es unknown
- 2019-02-21 BR BR112020016989-7A patent/BR112020016989A2/pt unknown
- 2019-02-21 AU AU2019224025A patent/AU2019224025B2/en active Active
- 2019-02-21 CN CN202510096498.4A patent/CN119932188A/zh active Pending
- 2019-02-21 SG SG11202007922XA patent/SG11202007922XA/en unknown
- 2019-02-21 US US16/281,315 patent/US11410748B2/en active Active
- 2019-02-21 EP EP25156901.8A patent/EP4538393A3/en active Pending
- 2019-02-21 CN CN201980027332.XA patent/CN112673115B/zh active Active
- 2019-02-21 CA CA3091647A patent/CA3091647A1/en active Pending
- 2019-02-21 JP JP2020544261A patent/JP7662337B2/ja active Active
- 2019-02-21 PL PL19709298.4T patent/PL3755816T3/pl unknown
- 2019-02-21 DK DK19709298.4T patent/DK3755816T3/da active
-
2020
- 2020-08-17 IL IL276748A patent/IL276748A/en unknown
- 2020-08-20 MX MX2025000449A patent/MX2025000449A/es unknown
-
2022
- 2022-07-26 US US17/815,102 patent/US20230298695A1/en not_active Abandoned
-
2025
- 2025-04-03 JP JP2025061707A patent/JP2025096376A/ja active Pending
- 2025-04-18 US US19/182,880 patent/US20260066046A1/en active Pending
- 2025-09-26 AU AU2025238057A patent/AU2025238057A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015021158A1 (en) * | 2013-08-06 | 2015-02-12 | Exosome Diagnostics, Inc. | Urine biomarker cohorts, gene expression signatures, and methods of use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019224025A1 (en) | 2020-09-10 |
| SG11202007922XA (en) | 2020-09-29 |
| IL276748A (en) | 2020-10-29 |
| WO2019165021A1 (en) | 2019-08-29 |
| CN112673115A (zh) | 2021-04-16 |
| US20260066046A1 (en) | 2026-03-05 |
| JP2021514624A (ja) | 2021-06-17 |
| US20190259471A1 (en) | 2019-08-22 |
| KR20200123450A (ko) | 2020-10-29 |
| EP4538393A2 (en) | 2025-04-16 |
| MX2025000449A (es) | 2025-03-07 |
| PL3755816T3 (pl) | 2025-06-30 |
| JP2025096376A (ja) | 2025-06-26 |
| CN119932188A (zh) | 2025-05-06 |
| KR20260018206A (ko) | 2026-02-06 |
| JP7662337B2 (ja) | 2025-04-15 |
| CA3091647A1 (en) | 2019-08-29 |
| MX2020008702A (es) | 2020-09-25 |
| BR112020016989A2 (pt) | 2020-12-29 |
| KR102921718B1 (ko) | 2026-02-03 |
| AU2025238057A1 (en) | 2025-11-27 |
| EP3755816B1 (en) | 2025-02-12 |
| EP4538393A3 (en) | 2025-07-02 |
| EP3755816A1 (en) | 2020-12-30 |
| US11410748B2 (en) | 2022-08-09 |
| DK3755816T3 (da) | 2025-04-28 |
| CN112673115B (zh) | 2025-02-18 |
| US20230298695A1 (en) | 2023-09-21 |
| ES3023842T3 (en) | 2025-06-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2019224025B2 (en) | Methods for prostate cancer detection and treatment | |
| AU2019201577B2 (en) | Cancer diagnostics using biomarkers | |
| AU2015334841B2 (en) | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities | |
| AU2015334842B2 (en) | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities | |
| AU2018210695B2 (en) | Molecular subtyping, prognosis, and treatment of bladder cancer | |
| RU2719194C2 (ru) | Оценка активности клеточных сигнальных путей с применением вероятностного моделирования экспрессии целевых генов | |
| KR102114412B1 (ko) | 위장관췌장 신경내분비 신생물 (GEP-NENs)의 예측 방법 | |
| RU2721130C2 (ru) | Оценка активности путей клеточной сигнализации с помощью линейной комбинации(ий) экспрессий генов-мишеней | |
| AU2016331663B2 (en) | Pathogen biomarkers and uses therefor | |
| US20190300967A1 (en) | Compositions and methods for predicting response and resistance to ctla4 blockade in melanoma using a gene expression signature | |
| WO2003042661A2 (en) | Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer | |
| KR20120082906A (ko) | 자가포식현상-향상 유전자 생성물의 조절을 통한 자가포식현상의 조절 방법 | |
| WO2021183218A1 (en) | Compositions and methods for modulating the interaction between ss18-ssx fusion oncoprotein and nucleosomes | |
| KR20140140069A (ko) | 전반적 발달장애의 진단 및 치료용 조성물 및 그 진단 및 치료 방법 | |
| CN101573453A (zh) | 使用生物学途径基因表达分析来预测淋巴结阴性原发性乳腺癌的远处转移的方法 | |
| CN101258249A (zh) | 检测黑素瘤的方法和试剂 | |
| US12366575B2 (en) | Chemical compositions and methods of use | |
| KR20200113237A (ko) | 결장암 검출 및 치료 모니터링을 위한 방법 | |
| JP2003304888A (ja) | 化合物の毒性予測のための方法 | |
| KR20040065524A (ko) | 백혈병을 검사 및 치료하는 방법 | |
| CN114127314A (zh) | 用于对乳腺癌的亚型(Subtype)进行鉴别或者分类的鉴别标志物遗传基因组、方法和套件 | |
| CN1704478A (zh) | 评估急性髓性白血病患者的方法 | |
| US20020137077A1 (en) | Genes regulated in activated T cells | |
| KR20070099564A (ko) | 급성 골수성 백혈병 환자를 평가하는 방법 | |
| KR20190126812A (ko) | 질환 진단용 바이오마커 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |