AU2019100951A4 - Anti microbial/probiotics/functional/medicinal chewing gum with plant based gum base - Google Patents

Anti microbial/probiotics/functional/medicinal chewing gum with plant based gum base Download PDF

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Publication number
AU2019100951A4
AU2019100951A4 AU2019100951A AU2019100951A AU2019100951A4 AU 2019100951 A4 AU2019100951 A4 AU 2019100951A4 AU 2019100951 A AU2019100951 A AU 2019100951A AU 2019100951 A AU2019100951 A AU 2019100951A AU 2019100951 A4 AU2019100951 A4 AU 2019100951A4
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Prior art keywords
gum base
gum
essential oil
chewing gum
natural
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AU2019100951A
Inventor
Mohammad Sharif Sharifi
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Australian Food And Pharmaceutical Industries
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Australian Food And Pharmaceutical Ind
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Priority claimed from AU2019902106A external-priority patent/AU2019902106A0/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A61K31/75—Polymers of hydrocarbons of ethene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/22—Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/08—Chewing gum characterised by the composition containing organic or inorganic compounds of the chewing gum base
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G4/123—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/02—Recovery or refining of essential oils from raw materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)

Abstract

The present invention provides a chewing gum base obtained from various species of the genus Pistacia. The gum base by itself cannot serve as a chewing gum, therefore, other ingredients are added. These additional ingredients might or might not be essential and are comparable to those used in conventional chewing gum. The final gum base might or might not be blended in a sigma mixer with Xylitol, Maltitol, flavouring and artificial sweeteners. This chewing gum can deliver vast majority of the orally taken medication, probiotics and supplements

Description

The present invention provides a chewing gum base obtained from various species of the genus Pistacia. The gum base by itself cannot serve as a chewing gum, therefore, other ingredients are added. These additional ingredients might or might not be essential and are comparable to those used in conventional chewing gum. The final gum base might or might not be blended in a sigma mixer with Xylitol, Maltitol, flavouring and artificial sweeteners.
This chewing gum can deliver vast majority of the orally taken medication, probiotics and supplements
2019100951 25 Aug 2019
ANTI MICROBIAL/PROBIOTICS/FUNCTIONAL /MEDICINAL CHEWING GUM WITH PLANT BASED GUM BASE
The invention is described in the following statement
ANTIMICROBIAL/PROBIOTICS/FUNCTIONAL/MEDICINAL CHEWING GUM WITH PLANT BASED GUM BASE
2019100951 25 Aug 2019
Mastic gum from various species of the genus Pistacia contains an unusually high molecular weight polymer which, based on our research and studies, possesses antimicrobial activities. The molecular weight of this polymer has a significant impact on both the antimicrobial activities and the elasticity texture of the gum. Measures must therefore be taken to maintain the molecular weight within a range that optimises both properties for use. Great care is given to terminate the naturally occurring free radical polymerisation within the resin, which increases the molecular weight of the polymer fraction which heightens antimicrobial activity but compromises elasticity. This is achieved through early harvesting or storage at a chilling temperature.
As the molecular weight of the polymer has significant impact on the antimicrobial activities, it is therefore necessary that the mastic gum used for probiotic chewing gum has a low molecular weight so as not to kill the probiotics, while still maintaining a suitable elasticity for chewing. In contrast, the mastic we use for encapsulation may possess a very high molecular weight.
The essential oil of the composite resin is extracted for use by an innovative and unique cold method, which prevents any negative impact on the polymerisation of the resin. The essential oil is also stored at low temperature as free radicals in the essential oil may initiate free radical polymerisation of Myrcene.
This oil is used as an antiseptic, insecticide, lice shampoo and mouth wash. We are also investing in the research sector to produce a wound healing bandage from this essential oil. This essential oil has also traditionally been used to dissolve kidney stones, a usage which yet requires animal and clinical trials unless it is used as a natural remedy.
The remining resin has three major fractions: the weak acidic fractions, the strong acidic fractions and the neutral fractions. Each possesses different biological
2019100951 25 Aug 2019 activities and impact on the gum's elasticity and taste in different ways. In order to have a suitable elasticity and a pleasant texture, it is important to reach a suitable ratio of these fractions.
The gum base by itself cannot serve as a chewing gum, therefore, other ingredients are added. These additional ingredients might or might not be essential and are comparable to those used in conventional chewing gum. The final gum base might or might not be blended in a sigma mixer with Xylitol, Maltitol, flavouring and artificial sweeteners. The remaining processes which roll, form, and coat the chewing gum pellets are carried out via conventional methods.
Conventional chewing gum is primarily made up of butadiene-based synthetic rubber which is non-biodegradable. Our product is distinctively unique as it is made from plant-based gums from a variety of trees, including — but not limited to — genus Pistacia. It is an environmentally friendly product that is biodegradable and offers health benefits of traditional medicine which have the support of evidencebased research and scientific papers.
This chewing gum can be produced with sugar or a sweetener. The preference is to use the sweetener, xylitol/isomalt which is diabetic-friendly — the former also possessing purported dental hygiene benefits. The chewing gum can also be nonflavoured or flavoured with a broad variety of flavours such as natural essential oils. Vitamins D, E, A, K or a multi vitamin, hemp products, cannabinoids, calcium, analgesics, sildenafil and other functional compounds can be incorporated into the gum base or its coating to produce medicinal/ supplement natural chewing gum. It can also be incorporated with Nitroglycerin to relieve angina as Nitroglycerin is released slowly while the gum is chewed. After the gum base is made, the functional compounds are mixed into the chewing gum itself, the coating or both.
2019100951 25 Aug 2019
Modified/non-antimicrobial plant base chewing gum can also be incorporated with probiotics:
• Lactococcus lactis ssp. lactis;
• Lactococcus lactis ssp. cremoris;
• Lactococcus lactis spp. lactis biovar diacetylactis;
• Lactobacilluys brevis;
• Leuconostoc spp.;
• the yeast Saccharomyces cerevisiae • Blis M18 and K12
In summary this chewing gum can deliver vast majority of the orally taken medication, probiotics and supplements.
2019100951 25 Aug 2019

Claims (14)

1. The gum base is made from natural resin and not from petrochemical, namely butadiene-based synthetic rubber, or natural latex.
2. The said gum base is therapeutic and possesses antimicrobial, antiviral, antitumor and cholesterol levelling properties.
3. The said gum base has gut health benefits, namely anti-helicobacter, beneficial to Inflammatory Bowel Diseases (IBS), including but not limited to Crohn's disease, reflux heartburn and periodontal disease — gingivitis.
4. The said gum base is distinctively unique as it is made from plant-based gums from a variety of trees, including — but not limited to — genus Pistacia.
5. The said gum base is an environmentally friendly product that is biodegradable and offers health benefits of traditional medicine which have the support of evidence-based research, clinical trials and scientific papers.
6. The said gum base is incorporated with functional/medicinal groups.
7. The modified said gum base is incorporated with prebiotic/probiotics.
8. The said gum base by itself cannot serve as a chewing gum, therefore, other ingredients are added. These additional ingredients might or might not be essential and are comparable to those used in conventional chewing gum.
9. The said gum base might or might not be blended in a sigma mixer with Xylitol, Maltitol, flavouring and artificial sweeteners.
2019100951 25 Aug 2019
10. This said gum can be blended with sugar or a sweetener. The preference is to use the sweetener, xylitol/isomalt which is diabetic-friendly — the former also possessing purported dental hygiene benefits.
11. The essential oil of the said gum is extracted for use by an innovative and unique cold method (vacuum followed by chilling process), which prevents any negative impact on the polymerisation of the resin. The essential oil is also stored at low temperature as remnant of free radicals in the essential oil may initiate free radical polymerisation of Myrcene.
12. The said essential oil is used as an antiseptic and healing remedy in the wound healing bandage.
13. The said essential oil is also used in natural mouth wash, natural lice shampoo, and natural insecticide.
14. The said essential oil is used in a remedy to dissolve kidney/bladder stones.
AU2019100951A 2019-06-18 2019-08-25 Anti microbial/probiotics/functional/medicinal chewing gum with plant based gum base Active AU2019100951A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2019902106A AU2019902106A0 (en) 2019-06-18 ANTI MICROBIAL PLANT BASED CHEWING GUM. Our product is made from plant based gums from a variety of trees which exhibit antimicrobial activity. It is an environmentally friendly product that is biodegradable and offers health benefits. The said gum base is obtained from trunk exudates (gums) from various trees including the Dipterocarpaceae family of trees, mainly those of the genera Shorea, Balanocarpus or Hopea, and trees of the genus Pistachia. The trunk exudates of the aforementioned trees are mainly composed of triterpenes and triterpenoids with well-known antimicrobial activities.
AU2019902106 2019-06-18
AU2019902275 2019-06-28
AU2019902275A AU2019902275A0 (en) 2019-06-28 Gum base made from australian native plants

Publications (1)

Publication Number Publication Date
AU2019100951A4 true AU2019100951A4 (en) 2019-10-03

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Application Number Title Priority Date Filing Date
AU2019100951A Active AU2019100951A4 (en) 2019-06-18 2019-08-25 Anti microbial/probiotics/functional/medicinal chewing gum with plant based gum base

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AU (1) AU2019100951A4 (en)

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