AU2018359635B2 - Antibodies against MFAP4 - Google Patents

Antibodies against MFAP4 Download PDF

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Publication number
AU2018359635B2
AU2018359635B2 AU2018359635A AU2018359635A AU2018359635B2 AU 2018359635 B2 AU2018359635 B2 AU 2018359635B2 AU 2018359635 A AU2018359635 A AU 2018359635A AU 2018359635 A AU2018359635 A AU 2018359635A AU 2018359635 B2 AU2018359635 B2 AU 2018359635B2
Authority
AU
Australia
Prior art keywords
antibody
ser
seq
has0326
thr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2018359635A
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English (en)
Other versions
AU2018359635A1 (en
AU2018359635A2 (en
Inventor
Uffe Holmskov
Grith LYKKE SØRENSEN
Anders Schlosser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southern Denmark
Original Assignee
University of Southern Denmark
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Southern Denmark filed Critical University of Southern Denmark
Publication of AU2018359635A1 publication Critical patent/AU2018359635A1/en
Publication of AU2018359635A2 publication Critical patent/AU2018359635A2/en
Application granted granted Critical
Publication of AU2018359635B2 publication Critical patent/AU2018359635B2/en
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Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2018359635A 2017-11-01 2018-11-01 Antibodies against MFAP4 Active AU2018359635B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17199552.5 2017-11-01
EP17199552 2017-11-01
PCT/EP2018/079949 WO2019086580A1 (en) 2017-11-01 2018-11-01 Antibodies against mfap4

Publications (3)

Publication Number Publication Date
AU2018359635A1 AU2018359635A1 (en) 2020-05-07
AU2018359635A2 AU2018359635A2 (en) 2020-05-21
AU2018359635B2 true AU2018359635B2 (en) 2024-11-14

Family

ID=60201899

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018359635A Active AU2018359635B2 (en) 2017-11-01 2018-11-01 Antibodies against MFAP4

Country Status (7)

Country Link
US (1) US11993649B2 (enExample)
EP (1) EP3704147A1 (enExample)
JP (1) JP7382343B2 (enExample)
CN (1) CN111315771B (enExample)
AU (1) AU2018359635B2 (enExample)
CA (1) CA3118361A1 (enExample)
WO (1) WO2019086580A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022218908A1 (en) 2021-04-12 2022-10-20 Syddansk Universitet Mfap4 and treatment of fibrosis
WO2025242098A1 (zh) * 2024-05-21 2025-11-27 康诺亚生物医药科技（成都）有限公司 针对ceacam5的抗体偶联药物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110059097A1 (en) * 2008-02-22 2011-03-10 University Health Network MFAP4 as a Marker For Regulatory Cells and Anti-Cancer Cells
JP5872805B2 (ja) 2011-07-07 2016-03-01 花王株式会社 Ｍｆａｐ−４産生促進剤
US9988442B2 (en) * 2013-01-23 2018-06-05 Syddansk Universitet MFAP4 binding antibodies blocking the interaction between MFAP4 and integrin receptors
WO2016008498A1 (en) 2014-07-17 2016-01-21 Syddansk Universitet Mfap4 binding antibody blocking the interaction between mfap4 and integrin receptors
CN106771201A (zh) * 2016-12-05 2017-05-31 江西惠肽生物科技有限公司 用于肝纤维化诊断试剂盒及其检测方法

Also Published As

Publication number Publication date
EP3704147A1 (en) 2020-09-09
CN111315771B (zh) 2023-10-27
CN111315771A (zh) 2020-06-19
AU2018359635A1 (en) 2020-05-07
JP7382343B2 (ja) 2023-11-16
US11993649B2 (en) 2024-05-28
AU2018359635A2 (en) 2020-05-21
US20230047179A1 (en) 2023-02-16
CA3118361A1 (en) 2019-05-09
JP2021513360A (ja) 2021-05-27
WO2019086580A1 (en) 2019-05-09

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT FILED 17 APR 2020

FGA Letters patent sealed or granted (standard patent)