AU2017442079A1 - Cromolyn compositions and methods thereof - Google Patents
Cromolyn compositions and methods thereof Download PDFInfo
- Publication number
- AU2017442079A1 AU2017442079A1 AU2017442079A AU2017442079A AU2017442079A1 AU 2017442079 A1 AU2017442079 A1 AU 2017442079A1 AU 2017442079 A AU2017442079 A AU 2017442079A AU 2017442079 A AU2017442079 A AU 2017442079A AU 2017442079 A1 AU2017442079 A1 AU 2017442079A1
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- AU
- Australia
- Prior art keywords
- cromolyn
- composition
- powder
- microns
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- 208000022256 primary systemic amyloidosis Diseases 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
- 229960004919 procaine Drugs 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 229940097325 prolactin Drugs 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000012383 pulmonary drug delivery Methods 0.000 description 1
- 208000005069 pulmonary fibrosis Diseases 0.000 description 1
- 230000009325 pulmonary function Effects 0.000 description 1
- 210000004879 pulmonary tissue Anatomy 0.000 description 1
- 229940051845 razadyne Drugs 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 229960004136 rivastigmine Drugs 0.000 description 1
- 150000003335 secondary amines Chemical class 0.000 description 1
- MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical group C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 description 1
- 229950001900 semagacestat Drugs 0.000 description 1
- 229940125390 short-acting beta agonist Drugs 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- KKEYFWRCBNTPAC-UHFFFAOYSA-L terephthalate(2-) Chemical compound [O-]C(=O)C1=CC=C(C([O-])=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-L 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- 229960000278 theophylline Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/830,980 US10525005B2 (en) | 2013-05-23 | 2017-12-04 | Cromolyn compositions and methods thereof |
| US15/830,980 | 2017-12-04 | ||
| PCT/US2017/064526 WO2019112552A1 (en) | 2017-12-04 | 2017-12-28 | Cromolyn compositions and methods thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2017442079A1 true AU2017442079A1 (en) | 2020-06-25 |
Family
ID=66751145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2017442079A Pending AU2017442079A1 (en) | 2017-12-04 | 2017-12-28 | Cromolyn compositions and methods thereof |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP3720429A4 (ja) |
| JP (1) | JP2021505658A (ja) |
| KR (1) | KR20200096567A (ja) |
| CN (1) | CN111629719A (ja) |
| AU (1) | AU2017442079A1 (ja) |
| CA (1) | CA3084593A1 (ja) |
| MX (1) | MX2020005615A (ja) |
| WO (1) | WO2019112552A1 (ja) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2466863A1 (en) * | 2001-11-29 | 2003-06-05 | Emisphere Technologies, Inc. | Oral pharmaceutical compositions comprising cromolyn sodium and an acylated amino acid |
| EP3563849A3 (en) * | 2012-10-25 | 2020-02-12 | The General Hospital Corporation | Combination therapies for the treatment of alzheimer's disease and related disorders |
| EP2999337A4 (en) * | 2013-05-23 | 2017-03-15 | Aztherapies, Inc | Methods for delivering cromolyn |
| EP3060205A4 (en) * | 2013-10-22 | 2017-06-28 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| US10265296B2 (en) * | 2015-08-07 | 2019-04-23 | Respivant Sciences Gmbh | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
| AU2016359674A1 (en) * | 2015-11-23 | 2018-06-14 | The General Hospital Corporation | Compositions and methods for treating ischemic stroke |
-
2017
- 2017-12-28 AU AU2017442079A patent/AU2017442079A1/en active Pending
- 2017-12-28 KR KR1020207018938A patent/KR20200096567A/ko not_active Application Discontinuation
- 2017-12-28 EP EP17934303.3A patent/EP3720429A4/en not_active Withdrawn
- 2017-12-28 WO PCT/US2017/064526 patent/WO2019112552A1/en unknown
- 2017-12-28 CN CN201780098153.6A patent/CN111629719A/zh active Pending
- 2017-12-28 JP JP2020548854A patent/JP2021505658A/ja active Pending
- 2017-12-28 MX MX2020005615A patent/MX2020005615A/es unknown
- 2017-12-28 CA CA3084593A patent/CA3084593A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20200096567A (ko) | 2020-08-12 |
| MX2020005615A (es) | 2020-11-25 |
| JP2021505658A (ja) | 2021-02-18 |
| CA3084593A1 (en) | 2019-06-13 |
| EP3720429A1 (en) | 2020-10-14 |
| CN111629719A (zh) | 2020-09-04 |
| WO2019112552A1 (en) | 2019-06-13 |
| EP3720429A4 (en) | 2021-09-15 |
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