AU2017315670B2 - Compositions comprising reversibly modified oligonucleotides and uses thereof - Google Patents

Compositions comprising reversibly modified oligonucleotides and uses thereof Download PDF

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Publication number
AU2017315670B2
AU2017315670B2 AU2017315670A AU2017315670A AU2017315670B2 AU 2017315670 B2 AU2017315670 B2 AU 2017315670B2 AU 2017315670 A AU2017315670 A AU 2017315670A AU 2017315670 A AU2017315670 A AU 2017315670A AU 2017315670 B2 AU2017315670 B2 AU 2017315670B2
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glutathione
formula
hydrogen
oligonucleotide
sensitive
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AU2017315670A1 (en
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Venkata KRISHNAMURTHY
Weimin Wang
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Dicerna Pharmaceuticals Inc
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Dicerna Pharmaceuticals Inc
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    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
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    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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AU2017315670A 2016-08-23 2017-08-23 Compositions comprising reversibly modified oligonucleotides and uses thereof Ceased AU2017315670B2 (en)

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AU2022204225A AU2022204225A1 (en) 2016-08-23 2022-06-16 Compositions Comprising Reversibly Modified Oligonucleotides And Uses Thereof

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US201662378635P 2016-08-23 2016-08-23
US62/378,635 2016-08-23
PCT/US2017/048239 WO2018039364A1 (en) 2016-08-23 2017-08-23 Compositions comprising reversibly modified oligonucleotides and uses thereof

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AU2017315670B2 true AU2017315670B2 (en) 2022-03-17

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US (2) US11390642B2 (enExample)
EP (1) EP3503730B1 (enExample)
JP (2) JP7249080B2 (enExample)
KR (1) KR102530513B1 (enExample)
CN (2) CN109890207B (enExample)
AU (2) AU2017315670B2 (enExample)
CA (1) CA3032165C (enExample)
IL (2) IL295212A (enExample)
MX (2) MX2019002075A (enExample)
WO (1) WO2018039364A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018045317A1 (en) * 2016-09-02 2018-03-08 Dicerna Pharmaceuticals, Inc. 4'-phosphate analogs and oligonucleotides comprising the same
AU2019205904A1 (en) 2018-01-05 2020-06-18 Dicerna Pharmaceuticals, Inc. Reducing beta-catenin and IDO expression to potentiate immunotherapy
EP3710588A4 (en) 2018-01-16 2021-08-18 Dicerna Pharmaceuticals, Inc. COMPOSITIONS AND METHODS TO INHIBIT ALDH2 EXPRESSION
AU2020252560A1 (en) 2019-04-04 2021-10-28 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting gene expression in the central nervous system
WO2021177657A1 (ko) * 2020-03-03 2021-09-10 주식회사 넥스모스 글루타치온에 특이적으로 결합하는 dna 압타머 및 그의 용도
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