AU2017302589A1 - Spatiotemporal regulators - Google Patents

Spatiotemporal regulators Download PDF

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Publication number
AU2017302589A1
AU2017302589A1 AU2017302589A AU2017302589A AU2017302589A1 AU 2017302589 A1 AU2017302589 A1 AU 2017302589A1 AU 2017302589 A AU2017302589 A AU 2017302589A AU 2017302589 A AU2017302589 A AU 2017302589A AU 2017302589 A1 AU2017302589 A1 AU 2017302589A1
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Australia
Prior art keywords
mirna
genetic construct
engineered genetic
target cells
cells
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Abandoned
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AU2017302589A
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English (en)
Inventor
Timothy Kuan-Ta Lu
Remus WONG
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Senti Biosciences Inc
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Senti Biosciences Inc
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Publication date
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Publication of AU2017302589A1 publication Critical patent/AU2017302589A1/en
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C12N2310/122—Hairpin
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
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    • C12N2310/141—MicroRNAs, miRNAs
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12N2310/30—Chemical structure
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    • C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)

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  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
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  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2017302589A 2016-07-26 2017-07-26 Spatiotemporal regulators Abandoned AU2017302589A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662366755P 2016-07-26 2016-07-26
US62/366,755 2016-07-26
PCT/US2017/043938 WO2018022749A1 (en) 2016-07-26 2017-07-26 Spatiotemporal regulators

Publications (1)

Publication Number Publication Date
AU2017302589A1 true AU2017302589A1 (en) 2019-02-28

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ID=59523304

Family Applications (2)

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AU2017302587A Abandoned AU2017302587A1 (en) 2016-07-26 2017-07-26 Genetic erasers
AU2017302589A Abandoned AU2017302589A1 (en) 2016-07-26 2017-07-26 Spatiotemporal regulators

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AU2017302587A Abandoned AU2017302587A1 (en) 2016-07-26 2017-07-26 Genetic erasers

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US (2) US20190233844A1 (enExample)
EP (2) EP3491137A1 (enExample)
JP (2) JP2019527563A (enExample)
KR (2) KR20190053180A (enExample)
CN (2) CN110088285A (enExample)
AU (2) AU2017302587A1 (enExample)
CA (2) CA3031673A1 (enExample)
WO (2) WO2018022749A1 (enExample)

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WO2018022747A1 (en) 2018-02-01
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JP2019521717A (ja) 2019-08-08
EP3491138A1 (en) 2019-06-05
CN110073000A (zh) 2019-07-30
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