AU2017204686B2 - Compositions and methods for detecting and treating esophageal cancer - Google Patents

Compositions and methods for detecting and treating esophageal cancer Download PDF

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Publication number
AU2017204686B2
AU2017204686B2 AU2017204686A AU2017204686A AU2017204686B2 AU 2017204686 B2 AU2017204686 B2 AU 2017204686B2 AU 2017204686 A AU2017204686 A AU 2017204686A AU 2017204686 A AU2017204686 A AU 2017204686A AU 2017204686 B2 AU2017204686 B2 AU 2017204686B2
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Australia
Prior art keywords
cdr
preferentially
antibodies
progastrin
antibody
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AU2017204686A
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AU2017204686A1 (en
Inventor
Alexandre PRIEUR
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Progastrine et Cancers SARL
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Progastrine et Cancers SARL
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Priority to AU2020202296A priority Critical patent/AU2020202296B2/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57557—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G01N33/57585—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2017204686A 2015-12-31 2017-01-02 Compositions and methods for detecting and treating esophageal cancer Active AU2017204686B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2020202296A AU2020202296B2 (en) 2015-12-31 2020-03-31 Compositions and methods for detecting and treating esophageal cancer

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15307189.9 2015-12-31
EP15307189 2015-12-31
EP16305139.4 2016-02-05
EP16305139 2016-02-05
PCT/EP2017/050037 WO2017114976A1 (en) 2015-12-31 2017-01-02 Compositions and methods for detecting and treating esophageal cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020202296A Division AU2020202296B2 (en) 2015-12-31 2020-03-31 Compositions and methods for detecting and treating esophageal cancer

Publications (2)

Publication Number Publication Date
AU2017204686A1 AU2017204686A1 (en) 2018-07-05
AU2017204686B2 true AU2017204686B2 (en) 2020-04-30

Family

ID=57821946

Family Applications (2)

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AU2017204686A Active AU2017204686B2 (en) 2015-12-31 2017-01-02 Compositions and methods for detecting and treating esophageal cancer
AU2020202296A Active AU2020202296B2 (en) 2015-12-31 2020-03-31 Compositions and methods for detecting and treating esophageal cancer

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Country Status (14)

Country Link
US (2) US11789021B2 (enExample)
EP (2) EP3848709B1 (enExample)
JP (2) JP7018885B2 (enExample)
KR (2) KR102197478B1 (enExample)
CN (1) CN108700589A (enExample)
AU (2) AU2017204686B2 (enExample)
BR (1) BR112018013272A2 (enExample)
CA (2) CA3193481A1 (enExample)
EA (1) EA037032B1 (enExample)
ES (2) ES3003287T3 (enExample)
PL (1) PL3397967T3 (enExample)
SG (1) SG11201805263TA (enExample)
WO (1) WO2017114976A1 (enExample)
ZA (1) ZA201804142B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US20240018264A1 (en) * 2015-12-31 2024-01-18 Progastrine Et Cancers S.À R.L. Compositions and methods for detecting and treating ovarian cancer
EP3720879B1 (en) * 2017-12-05 2022-05-11 Progastrine et Cancers S.à r.l. Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
AU2018381046B2 (en) 2017-12-08 2025-10-02 Ecs-Biotracker Sàrl Radiolabeled progastrin in cancer diagnosis
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ｅｃｓ前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
WO2019166499A1 (en) 2018-02-27 2019-09-06 Ecs-Progastrin Sa Progastrin as a biomarker for immunotherapy
CA3093053A1 (en) * 2018-03-13 2019-09-19 Creatv Microtech, Inc. Methods for monitoring treatment response and disease progression in subjects using circulating cells
KR102167078B1 (ko) * 2019-07-19 2020-10-16 (주)파즈코리아 혈액 샘플 이송 장치
US20220356532A1 (en) * 2019-10-24 2022-11-10 The Johns Hopkins University Compositions and methods for detecting and treating esophageal cancer
JP7287532B2 (ja) * 2020-08-04 2023-06-06 王子ホールディングス株式会社 トイレットロール

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2011083091A2 (en) * 2010-01-08 2011-07-14 Bioréalités S.A.S. Methods for treating pancreatic cancer

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Also Published As

Publication number Publication date
EA201891527A1 (ru) 2019-01-31
ES2861587T3 (es) 2021-10-06
EP3848709A1 (en) 2021-07-14
KR102430893B1 (ko) 2022-08-09
EP3397967B1 (en) 2020-12-30
CA3193481A1 (en) 2017-07-06
JP2022064969A (ja) 2022-04-26
AU2017204686A1 (en) 2018-07-05
AU2020202296B2 (en) 2022-06-02
CN108700589A (zh) 2018-10-23
PL3397967T3 (pl) 2021-06-28
US20240085423A1 (en) 2024-03-14
CA3009785A1 (en) 2017-07-06
EP3848709B1 (en) 2024-12-04
US11789021B2 (en) 2023-10-17
EP3848709C0 (en) 2024-12-04
KR102197478B1 (ko) 2021-01-04
JP7363007B2 (ja) 2023-10-18
KR20180108586A (ko) 2018-10-04
SG11201805263TA (en) 2018-07-30
AU2020202296A1 (en) 2020-04-23
JP2019505785A (ja) 2019-02-28
EA037032B1 (ru) 2021-01-28
JP7018885B2 (ja) 2022-02-14
BR112018013272A2 (en) 2018-12-11
US20190011447A1 (en) 2019-01-10
EP3397967A1 (en) 2018-11-07
WO2017114976A1 (en) 2017-07-06
ZA201804142B (en) 2019-11-27
ES3003287T3 (en) 2025-03-10
KR20210002363A (ko) 2021-01-07

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