AU2016343840A1 - Mucus penetrating particles with high molecular weight and dense coatings - Google Patents
Mucus penetrating particles with high molecular weight and dense coatings Download PDFInfo
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- AU2016343840A1 AU2016343840A1 AU2016343840A AU2016343840A AU2016343840A1 AU 2016343840 A1 AU2016343840 A1 AU 2016343840A1 AU 2016343840 A AU2016343840 A AU 2016343840A AU 2016343840 A AU2016343840 A AU 2016343840A AU 2016343840 A1 AU2016343840 A1 AU 2016343840A1
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- Prior art keywords
- peg
- poly
- particles
- kda
- mucus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 239000005019 zein Substances 0.000 description 1
- 229940093612 zein Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562248432P | 2015-10-30 | 2015-10-30 | |
| US62/248,432 | 2015-10-30 | ||
| PCT/US2016/059661 WO2017075565A1 (en) | 2015-10-30 | 2016-10-31 | Mucus penetrating particles with high molecular weight and dense coatings |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2016343840A1 true AU2016343840A1 (en) | 2018-06-07 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016343840A Abandoned AU2016343840A1 (en) | 2015-10-30 | 2016-10-31 | Mucus penetrating particles with high molecular weight and dense coatings |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10668025B2 (enExample) |
| EP (1) | EP3368008A1 (enExample) |
| JP (1) | JP2018533579A (enExample) |
| KR (1) | KR20180075650A (enExample) |
| CN (1) | CN108472250A (enExample) |
| AU (1) | AU2016343840A1 (enExample) |
| CA (1) | CA3003733C (enExample) |
| WO (1) | WO2017075565A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8957034B2 (en) * | 2004-01-28 | 2015-02-17 | Johns Hopkins University | Drugs and gene carrier particles that rapidly move through mucous barriers |
| WO2011106702A2 (en) | 2010-02-25 | 2011-09-01 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
| WO2012076877A1 (en) | 2010-12-06 | 2012-06-14 | Autifony Therapeutics Limited | Hydantoin derivatives useful as kv3 inhibitors |
| AU2012351994B2 (en) * | 2011-12-14 | 2015-11-05 | The Johns Hopkins University | Nanoparticles with enhanced mucosal penetration or decreased inflammation |
| WO2019175290A1 (en) | 2018-03-13 | 2019-09-19 | Beckley Canopy Therapeutics Limited | Cannabis or cannabis derived compositions for promoting cessation of chemical dependence |
| CA3110773C (en) | 2018-09-11 | 2023-02-28 | Lead Biotherapeutics Ltd. | Mucoadhesive dispersion nanoparticle system and method for production the same |
| EP4164598A1 (en) * | 2020-06-11 | 2023-04-19 | Janssen Biotech, Inc. | Controlled release of self-embedding particles for localized drug delivery |
| JP2022130270A (ja) * | 2021-02-25 | 2022-09-06 | シンバイオシス株式会社 | 腸管吸収用補助剤及びその利用方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5565215A (en) * | 1993-07-23 | 1996-10-15 | Massachusettes Institute Of Technology | Biodegradable injectable particles for imaging |
| US8957034B2 (en) * | 2004-01-28 | 2015-02-17 | Johns Hopkins University | Drugs and gene carrier particles that rapidly move through mucous barriers |
| ES2360538T3 (es) * | 2006-09-08 | 2011-06-06 | Johns Hopkins University | Composiciones para aumentar el transporte a través de moco. |
| WO2012039979A2 (en) * | 2010-09-10 | 2012-03-29 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
| CA2816977C (en) * | 2010-11-05 | 2019-10-29 | The Johns Hopkins University | Compositions and methods relating to reduced mucoadhesion |
| ES2385995B2 (es) * | 2011-01-10 | 2013-05-21 | Universidade De Santiago De Compostela | Nanocápsulas con cubierta polimérica |
| AU2012351994B2 (en) * | 2011-12-14 | 2015-11-05 | The Johns Hopkins University | Nanoparticles with enhanced mucosal penetration or decreased inflammation |
| KR101811917B1 (ko) * | 2012-01-19 | 2017-12-22 | 더 존스 홉킨스 유니버시티 | 점액 침투 강화를 나타내는 나노 입자 제형 |
| NZ741873A (en) * | 2012-05-03 | 2019-04-26 | Kala Pharmaceuticals Inc | Pharmaceutical nanoparticles showing improved mucosal transport |
| KR102154880B1 (ko) | 2012-05-03 | 2020-09-10 | 칼라 파마슈티컬스, 인크. | 개선된 점막 수송을 나타내는 제약 나노입자 |
| HK1208377A1 (en) * | 2012-05-04 | 2016-03-04 | The Johns Hopkins University | Lipid-based drug carriers for rapid penetration through mucus linings |
-
2016
- 2016-10-31 KR KR1020187015274A patent/KR20180075650A/ko not_active Withdrawn
- 2016-10-31 CN CN201680075874.0A patent/CN108472250A/zh active Pending
- 2016-10-31 JP JP2018522081A patent/JP2018533579A/ja active Pending
- 2016-10-31 EP EP16795204.3A patent/EP3368008A1/en not_active Withdrawn
- 2016-10-31 US US15/771,961 patent/US10668025B2/en active Active
- 2016-10-31 CA CA3003733A patent/CA3003733C/en active Active
- 2016-10-31 AU AU2016343840A patent/AU2016343840A1/en not_active Abandoned
- 2016-10-31 WO PCT/US2016/059661 patent/WO2017075565A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA3003733C (en) | 2021-04-20 |
| CA3003733A1 (en) | 2017-05-04 |
| WO2017075565A1 (en) | 2017-05-04 |
| KR20180075650A (ko) | 2018-07-04 |
| CN108472250A (zh) | 2018-08-31 |
| US20180221293A1 (en) | 2018-08-09 |
| JP2018533579A (ja) | 2018-11-15 |
| US10668025B2 (en) | 2020-06-02 |
| EP3368008A1 (en) | 2018-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |