AU2016318163B2 - Genetically-engineered drug resistant T cells and methods of using the same - Google Patents

Genetically-engineered drug resistant T cells and methods of using the same Download PDF

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AU2016318163B2
AU2016318163B2 AU2016318163A AU2016318163A AU2016318163B2 AU 2016318163 B2 AU2016318163 B2 AU 2016318163B2 AU 2016318163 A AU2016318163 A AU 2016318163A AU 2016318163 A AU2016318163 A AU 2016318163A AU 2016318163 B2 AU2016318163 B2 AU 2016318163B2
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cells
cancer
cell composition
cell
subject
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AU2016318163A1 (en
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G. Yancey Gillespie
Lawrence S. Lamb
H. Trent SPENCER
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Emory University
UAB Research Foundation
Children's Healthcare of Atlanta
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Emory University
UAB Research Foundation
Children's Healthcare of Atlanta
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
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AU2016318163A 2015-09-03 2016-09-06 Genetically-engineered drug resistant T cells and methods of using the same Active AU2016318163B2 (en)

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US201562214071P 2015-09-03 2015-09-03
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EP (3) EP4295914A3 (enExample)
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CN (1) CN108291209A (enExample)
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CA3044393A1 (en) * 2016-12-09 2018-06-14 The Uab Research Foundation Chimeric chlorotoxin receptors
GB201715918D0 (en) * 2017-09-29 2017-11-15 Tc Biopharm Ltd Modified CAR-T
WO2020010341A1 (en) * 2018-07-05 2020-01-09 Emory University Transduction of innate immunocompetent cells using aav6
EP3822342A4 (en) 2018-07-13 2022-08-03 Kyoto University METHOD OF PRODUCTION OF GAMMA DELTA T-CELLS
CN112384231A (zh) * 2018-08-26 2021-02-19 奥伊斯细胞生物技术公司 用于治疗胶质母细胞瘤的方法
JP7638864B2 (ja) * 2018-11-08 2025-03-04 イン８バイオ、インコーポレイテッド 癌を処置するための組成物および方法

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EP4006146B1 (en) 2023-09-06
JP7186615B2 (ja) 2022-12-09
AU2016318163A1 (en) 2018-03-29
US20180250337A1 (en) 2018-09-06
EP4295914A3 (en) 2024-04-10
ES2910709T3 (es) 2022-05-13
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ES2965437T3 (es) 2024-04-15
AU2022235516A1 (en) 2022-10-13
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US20250073228A1 (en) 2025-03-06
IL257763B (en) 2021-05-31
IL257763A (en) 2018-04-30
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WO2017041106A1 (en) 2017-03-09
EP3344760B1 (en) 2022-01-12
KR20180086183A (ko) 2018-07-30
CA2997547A1 (en) 2017-03-09
JP2022184987A (ja) 2022-12-13
CN108291209A (zh) 2018-07-17
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