AU2016299548A1 - Pharmaceutical composition with improved storage stability and method for preparing the same - Google Patents

Pharmaceutical composition with improved storage stability and method for preparing the same Download PDF

Info

Publication number
AU2016299548A1
AU2016299548A1 AU2016299548A AU2016299548A AU2016299548A1 AU 2016299548 A1 AU2016299548 A1 AU 2016299548A1 AU 2016299548 A AU2016299548 A AU 2016299548A AU 2016299548 A AU2016299548 A AU 2016299548A AU 2016299548 A1 AU2016299548 A1 AU 2016299548A1
Authority
AU
Australia
Prior art keywords
pharmaceutical composition
weight
pct
composition according
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2016299548A
Other languages
English (en)
Inventor
Bong Oh Kim
Hye Rim Kim
Ji Yeong Kim
Kyu Jin Kyung
Bum Chan MIN
Min Hyo Seo
Yil Woong Yi
Yoo Jeong YOON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Samyang Biopharmaceuticals Corp
Original Assignee
Samyang Biopharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samyang Biopharmaceuticals Corp filed Critical Samyang Biopharmaceuticals Corp
Publication of AU2016299548A1 publication Critical patent/AU2016299548A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2016299548A 2015-07-28 2016-07-28 Pharmaceutical composition with improved storage stability and method for preparing the same Abandoned AU2016299548A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20150106629 2015-07-28
KR10-2015-0106629 2015-07-28
PCT/KR2016/008270 WO2017018820A1 (en) 2015-07-28 2016-07-28 Pharmaceutical composition with improved storage stability and method for preparing the same

Publications (1)

Publication Number Publication Date
AU2016299548A1 true AU2016299548A1 (en) 2018-02-22

Family

ID=57884713

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016299548A Abandoned AU2016299548A1 (en) 2015-07-28 2016-07-28 Pharmaceutical composition with improved storage stability and method for preparing the same

Country Status (13)

Country Link
EP (1) EP3328437A4 (zh)
JP (1) JP2018521105A (zh)
KR (1) KR101787453B1 (zh)
CN (1) CN107466231A (zh)
AU (1) AU2016299548A1 (zh)
BR (1) BR112018001737A2 (zh)
CA (1) CA2993928A1 (zh)
HK (1) HK1249441A1 (zh)
IL (1) IL257187A (zh)
MX (1) MX2018001223A (zh)
RU (1) RU2018107055A (zh)
WO (1) WO2017018820A1 (zh)
ZA (1) ZA201801187B (zh)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6020507A (en) 1998-03-02 2000-02-01 Bristol-Myers Squibb Company Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile
EP1280557B1 (en) * 2000-05-12 2012-06-20 Samyang Corporation Method for the preparation of polymeric micelle via phase separation of block copolymer
US7217770B2 (en) * 2000-05-17 2007-05-15 Samyang Corporation Stable polymeric micelle-type drug composition and method for the preparation thereof
NZ532198A (en) * 2001-10-18 2006-03-31 Samyang Corp Polymeric micelle composition of an amphiphilic block copolymer and a polylactic acid derivative
WO2005037840A1 (en) 2003-10-16 2005-04-28 Mayne Pharma (Usa), Inc. Method for inverting the c2’ hydroxyl group of taxane esters
KR101024742B1 (ko) * 2007-12-31 2011-03-24 주식회사 삼양사 탁산 함유 양친성 블록 공중합체 미셀 조성물 및 그 제조방법
US9801818B2 (en) * 2007-12-31 2017-10-31 Samyang Biopharmaceuticals Corporation Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug
RU2459840C2 (ru) * 2007-12-31 2012-08-27 Самъянг Корпорейшн АМФИФИЛЬНЫЙ СОПОЛИМЕР ВЫСОКОЙ ЧИСТОТЫ, СОДЕРЖАЩИЙ ГИДРОФОБНЫЙ БЛОК ИЗ α-ГИДРОКСИКИСЛОТЫ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ
EP2201935B1 (en) * 2008-12-26 2020-07-08 Samyang Biopharmaceuticals Corporation Polymeric micelle composition containing a poorly soluble drug and preparation method of the same

Also Published As

Publication number Publication date
HK1249441A1 (zh) 2018-11-02
RU2018107055A3 (zh) 2019-08-28
CN107466231A (zh) 2017-12-12
RU2018107055A (ru) 2019-08-28
JP2018521105A (ja) 2018-08-02
MX2018001223A (es) 2018-11-09
KR20170015200A (ko) 2017-02-08
WO2017018820A1 (en) 2017-02-02
CA2993928A1 (en) 2017-02-02
BR112018001737A2 (pt) 2018-09-11
IL257187A (en) 2018-03-29
EP3328437A1 (en) 2018-06-06
KR101787453B1 (ko) 2017-10-19
ZA201801187B (en) 2018-12-19
EP3328437A4 (en) 2019-03-20

Similar Documents

Publication Publication Date Title
US11179466B2 (en) Amphiphilic block copolymer composition having enhanced micelle stability, and pharmaceutical composition comprising same
JP2016528187A (ja) ドセタキセルのナノポリマーミセルの凍結乾燥製剤及びその調製方法
US11464861B2 (en) Pharmaceutical composition with improved storage stability and method for preparing the same
US10739319B2 (en) Method for analyzing related substances of a pharmaceutical composition containing a polymeric carrier
AU2016299546B2 (en) Pharmaceutical composition with improved storage stability and method for preparing the same
US20170028066A1 (en) Pharmaceutical composition with improved storage stability and method for preparing the same
JP6605706B2 (ja) 保存安定性が向上した医薬組成物及びその製造方法
US20170028067A1 (en) Pharmaceutical composition with improved storage stability and method for preparing the same
US20170027866A1 (en) Pharmaceutical composition with improved storage stability and method for preparing the same
AU2016299547A1 (en) Pharmaceutical composition with improved storage stability and method for preparing the same
AU2016299548A1 (en) Pharmaceutical composition with improved storage stability and method for preparing the same
KR20170014058A (ko) 양친성 블록 공중합체의 정제방법, 이로부터 얻어지는 양친성 블록 공중합체, 및 이를 포함하는 약학 조성물

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted