AU2016267047A1 - Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms - Google Patents

Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms Download PDF

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Publication number
AU2016267047A1
AU2016267047A1 AU2016267047A AU2016267047A AU2016267047A1 AU 2016267047 A1 AU2016267047 A1 AU 2016267047A1 AU 2016267047 A AU2016267047 A AU 2016267047A AU 2016267047 A AU2016267047 A AU 2016267047A AU 2016267047 A1 AU2016267047 A1 AU 2016267047A1
Authority
AU
Australia
Prior art keywords
seq
igy
composition
oral
igy antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2016267047A
Other languages
English (en)
Inventor
Monica DIAS FIGUEIREDO
Robert Nordgren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of AU2016267047A1 publication Critical patent/AU2016267047A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/982—Reproductive organs; Embryos, Eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/11—Immunoglobulins specific features characterized by their source of isolation or production isolated from eggs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/23—Immunoglobulins specific features characterized by taxonomic origin from birds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Fodder In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2016267047A 2015-05-27 2016-05-23 Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms Abandoned AU2016267047A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562167082P 2015-05-27 2015-05-27
US62/167,082 2015-05-27
PCT/US2016/033821 WO2016191389A2 (fr) 2015-05-27 2016-05-23 Compositions contenant des anticorps igy antimicrobiens, pour le traitement et la prévention de troubles et de maladies causés par des micro-organismes compromettant la santé orale (ohc)

Publications (1)

Publication Number Publication Date
AU2016267047A1 true AU2016267047A1 (en) 2017-12-21

Family

ID=56550295

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016267047A Abandoned AU2016267047A1 (en) 2015-05-27 2016-05-23 Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms

Country Status (4)

Country Link
US (1) US20160347829A1 (fr)
EP (1) EP3303385A2 (fr)
AU (1) AU2016267047A1 (fr)
WO (1) WO2016191389A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2328914B1 (fr) * 2008-08-29 2017-05-10 Oral Health Australia Pty Ltd Prévention, traitement et diagnostic de l'infection à p. gingivalis
EP3490602A4 (fr) * 2016-08-01 2020-03-25 Scaled Microbiomics, LLC Systèmes et procédés de modification du microbiome pour réduire le risque de maladie et les manifestations de la maladie
WO2019021191A1 (fr) * 2017-07-26 2019-01-31 Tgx Soft Chew, Llc Produit à mâcher mou exempt d'amidon pour applications vétérinaires
CN108272649B (zh) * 2018-04-02 2021-01-29 广东药科大学 一种含IgY的澄清漱口液及其制备方法
CN108728388A (zh) * 2018-07-24 2018-11-02 上海美加净日化有限公司 牙龈卟啉单胞菌、抗牙龈卟啉单胞菌特异性IgY制剂及复配牙膏
CN108939068A (zh) * 2018-08-24 2018-12-07 江苏润洁生物科技有限公司 一种防治口腔疾病的组合物及其制备的口腔喷剂
CN109251247A (zh) * 2018-08-31 2019-01-22 菏泽睿智科技开发有限公司 一种幽门螺旋杆菌卵黄抗体的提取方法
US11337413B2 (en) 2019-12-10 2022-05-24 Woodstream Corporation Spider and insect trap with lure compartment
EP4102987A4 (fr) * 2020-02-10 2024-04-24 Mars Inc Produit sec expansé pour améliorer l'hygiène dentaire d'un animal de compagnie
EP4146277A1 (fr) * 2020-05-08 2023-03-15 Camas Incorporated Réduction de la transmission d'une maladie virale par des anticorps aviaires
US11319382B1 (en) 2021-06-28 2022-05-03 King Abdulaziz University Methods for producing and using IgY antibodies targeting the middle east respiratory syndrome coronavirus spike protein to treat or prevent MERS-CoV infection
CN114617088A (zh) * 2022-03-14 2022-06-14 海南金雨海洋产业发展有限公司 一种提高东风螺免疫力的养殖方法

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3486186A (en) 1967-05-08 1969-12-30 Hollymatic Corp Molding apparatus
US3887964A (en) 1972-01-24 1975-06-10 Formax Inc Food patty molding machine
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS4914624A (fr) 1972-06-08 1974-02-08
US3952478A (en) 1974-10-10 1976-04-27 Formax, Inc. Vacuum sheet applicator
US4054967A (en) 1975-10-20 1977-10-25 Formax, Inc. Food patty molding machine
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4144352A (en) 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4182003A (en) 1978-02-28 1980-01-08 Formax, Inc. Food patty molding machine
US4203976A (en) 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4338702A (en) 1979-03-29 1982-07-13 Holly Harry H Apparatus for making a ground food patty
US4334339A (en) 1980-05-12 1982-06-15 Hollymatic Corporation Mold device with movable compression insert
US4356595A (en) 1980-11-07 1982-11-02 Formax, Inc. Method and apparatus for molding food patties
US4343068A (en) 1981-01-19 1982-08-10 Holly James A Method and apparatus for unidirectional formation of a plug-formed patty with cleanout feature
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4372008A (en) 1981-04-23 1983-02-08 Formax, Inc. Food patty molding machine with multi-orifice fill passage and stripper plate
CH657506A5 (de) 1981-12-10 1986-09-15 Hollymatic Ag Portioniermaschine zum fuellen von hohlraeumen mit verformbarem material und verwendung derselben.
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4535505A (en) 1982-11-23 1985-08-20 Holly Systems, Inc. Method and apparatus for forming a patty to accommodate tissue fiber flow
US4608731A (en) 1983-01-11 1986-09-02 Holly Systems, Inc. Food patty with improved void structure, shape, and strength and method and apparatus for forming said patty
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US4523520A (en) 1984-01-17 1985-06-18 North Side Packing Company Meat processing equipment
US4597135A (en) 1984-02-21 1986-07-01 Holly Systems, Inc. Food patty forming method and apparatus employing two or more agitator bars
EP0237482A1 (fr) 1986-03-06 1987-09-16 Ciba-Geigy Ag Dérivés de la C(29)-carbonyloxy-milbémycine pour la lutte contre les parasites d'espèces végétales ou animales
RU2024527C1 (ru) 1986-03-25 1994-12-15 Санкио Компани Лимитед Способ получения макролидных соединений
US4768941A (en) 1986-06-16 1988-09-06 Hollymatic Corporation Food patty and machine and method for making thereof
DE3778768D1 (de) 1986-07-02 1992-06-11 Ciba Geigy Ag Pestizide.
US4697308A (en) 1986-10-29 1987-10-06 Formax, Inc. Patty molding mechanism for whole fiber food product
DE3636882C1 (de) 1986-10-30 1988-05-19 Schreiber Berthold Vorrichtung zur feinblasigen Einleitung eines Gases in eine Fluessigkeit
US4780931A (en) 1987-02-13 1988-11-01 Marlen Research Corporation Feeding device for patty forming machine
US4855317A (en) 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
US4874749A (en) 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
EP0319142B1 (fr) 1987-11-03 1994-04-06 Beecham Group Plc Intermédiaires pour la preparation des antibiotiques macrolides à activité anthelmintique
US4821376A (en) 1988-06-02 1989-04-18 Formax, Inc. Seal-off for food patty molding machine with multi-orifice fill passage and stripper plate
US4872241A (en) 1988-10-31 1989-10-10 Formax, Inc. Patty molding mechanism for fibrous food product
NZ232422A (en) 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
US5021025A (en) 1989-09-12 1991-06-04 Wagner Richard C Method and machine for making food patties
US4975039A (en) 1989-09-18 1990-12-04 Dare Gary L Food molding and portioning apparatus
US4996743A (en) 1990-01-29 1991-03-05 Formax, Inc. Mold plate drive linkage
US5022888A (en) 1990-05-03 1991-06-11 Formax, Inc. Co-forming apparatus for food patty molding machine
NZ247278A (en) 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
US5165218A (en) 1991-06-20 1992-11-24 Callahan Jr Bernard C Automatic sorting, stacking and packaging apparatus and method
US5345377A (en) 1992-10-30 1994-09-06 Electric Power Research Institute, Inc. Harmonic controller for an active power line conditioner
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
AUPM969994A0 (en) 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
IE80657B1 (en) 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
US6010710A (en) 1996-03-29 2000-01-04 Merial Direct pour-on skin solution for antiparasitic use in cattle and sheep
FR2752525B1 (fr) 1996-08-20 2000-05-05 Rhone Merieux Procede de lutte contre les myiases des cheptels bovins et ovins et compositions pour la mise en oeuvre de ce procede
US5885607A (en) 1996-03-29 1999-03-23 Rhone Merieux N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs
US5735603A (en) 1996-05-03 1998-04-07 Littleford Day, Inc. Horizontal mixer apparatus and method with improved shaft and seal structure
US5655436A (en) 1996-08-29 1997-08-12 Progressive Technology Of Manitowoc, Inc. Food patty molding machine
US5730650A (en) 1996-08-29 1998-03-24 Progressive Technology Of Wisconsin, Inc. Food patty molding machine
US6998131B2 (en) 1996-09-19 2006-02-14 Merial Limited Spot-on formulations for combating parasites
US6174540B1 (en) 1998-09-14 2001-01-16 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated caster oil
US6498153B1 (en) 1998-12-31 2002-12-24 Akzo Nobel N.V. Extended release growth promoting two component composition
AUPQ485999A0 (en) 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
CN100506847C (zh) * 2003-02-25 2009-07-01 雅臣药业集团（远东）有限公司 用于防治口腔疾病的IgY制备方法以及基于该IgY的牙膏
CN101098827B (zh) 2004-11-11 2011-06-15 巴塞尔聚烯烃意大利有限责任公司 由含有钛化合物的废液制备TiO2粉末的方法
WO2006084129A2 (fr) * 2005-02-01 2006-08-10 University Of Florida Research Foundation Genes du porphyromonas gingivalis w83 impliques dans l'invasion des cellules humaines
CN101511795B (zh) 2006-07-05 2013-09-18 安万特农业公司 1-芳基-5-烷基吡唑衍生化合物、其制备方法和使用方法
JP2009173558A (ja) * 2008-01-22 2009-08-06 Gen Corp:Kk 抗イヌ歯周病組成物
US9366673B2 (en) * 2009-08-02 2016-06-14 Sanofi Pasteur Limited Porphyromonas gingivalis polypeptides
WO2014142781A1 (fr) * 2013-03-11 2014-09-18 Whei-Chyou Wu Dispositif de commande d'un champ électrique élevé

Also Published As

Publication number Publication date
WO2016191389A2 (fr) 2016-12-01
US20160347829A1 (en) 2016-12-01
EP3303385A2 (fr) 2018-04-11
WO2016191389A3 (fr) 2017-01-05

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