AU2016209321B2 - Anthelmintic compounds, compositions and method of using thereof - Google Patents
Anthelmintic compounds, compositions and method of using thereof Download PDFInfo
- Publication number
- AU2016209321B2 AU2016209321B2 AU2016209321A AU2016209321A AU2016209321B2 AU 2016209321 B2 AU2016209321 B2 AU 2016209321B2 AU 2016209321 A AU2016209321 A AU 2016209321A AU 2016209321 A AU2016209321 A AU 2016209321A AU 2016209321 B2 AU2016209321 B2 AU 2016209321B2
- Authority
- AU
- Australia
- Prior art keywords
- diyl
- alkyl
- ring
- group
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 CC(C(C=CC(*1CCC(CCC(C=C2)=CC(O[C@](CC3)CC[C@@]3Nc3ccc(C(C(F)(F)F)C=O)cc3)=CC2=C)CC1)=*=C)=CC)(F)F Chemical compound CC(C(C=CC(*1CCC(CCC(C=C2)=CC(O[C@](CC3)CC[C@@]3Nc3ccc(C(C(F)(F)F)C=O)cc3)=CC2=C)CC1)=*=C)=CC)(F)F 0.000 description 3
- LZRDHSFPLUWYAX-UHFFFAOYSA-N CC(C)(C)OC(N(CC1)CCC1N)=O Chemical compound CC(C)(C)OC(N(CC1)CCC1N)=O LZRDHSFPLUWYAX-UHFFFAOYSA-N 0.000 description 1
- DQEVDFQAYLIBRD-UHFFFAOYSA-N FC(c(cc1)ccc1N=C=S)(F)F Chemical compound FC(c(cc1)ccc1N=C=S)(F)F DQEVDFQAYLIBRD-UHFFFAOYSA-N 0.000 description 1
- ZIDIKYIZXMYHAW-UHFFFAOYSA-N Fc1cccc(Br)n1 Chemical compound Fc1cccc(Br)n1 ZIDIKYIZXMYHAW-UHFFFAOYSA-N 0.000 description 1
- QRJZUBHXSIPIED-IRJFHVNHSA-N N#Cc(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1cc(N2CCNCC2)cnc1 Chemical compound N#Cc(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1cc(N2CCNCC2)cnc1 QRJZUBHXSIPIED-IRJFHVNHSA-N 0.000 description 1
- LCCPQUYXMFXCAC-UHFFFAOYSA-N N#Cc(cc1)c(C(F)(F)F)cc1F Chemical compound N#Cc(cc1)c(C(F)(F)F)cc1F LCCPQUYXMFXCAC-UHFFFAOYSA-N 0.000 description 1
- BMZBLAAHJGEMLV-CZMCAQCFSA-N [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1O)=O Chemical compound [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1O)=O BMZBLAAHJGEMLV-CZMCAQCFSA-N 0.000 description 1
- PQCAFPJBOYTKKS-LSNLESRRSA-N [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1cc(N(CC2)CCN2C(Nc2ccc(C(F)(F)F)cc2)=S)ccn1)=O Chemical compound [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1cc(N(CC2)CCN2C(Nc2ccc(C(F)(F)F)cc2)=S)ccn1)=O PQCAFPJBOYTKKS-LSNLESRRSA-N 0.000 description 1
- GQZYIKUZOWPSCO-RZDIXWSQSA-N [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1cc(N2CCNCC2)ccn1)=O Chemical compound [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1cc(N2CCNCC2)ccn1)=O GQZYIKUZOWPSCO-RZDIXWSQSA-N 0.000 description 1
- NSWJOOISVIONAW-AULYBMBSSA-N [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1nc(Br)ccc1)=O Chemical compound [O-][N+](c(c(C(F)(F)F)c1)ccc1N[C@H](CC1)CC[C@@H]1Oc1nc(Br)ccc1)=O NSWJOOISVIONAW-AULYBMBSSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2019202773A AU2019202773B2 (en) | 2015-01-20 | 2019-04-18 | Anthelmintic Compounds, Compositions And Method Of Using Thereof |
| AU2020204400A AU2020204400A1 (en) | 2015-01-20 | 2020-06-30 | Anthelmintic compounds, compositions and method of using thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562105463P | 2015-01-20 | 2015-01-20 | |
| US62/105,463 | 2015-01-20 | ||
| PCT/US2016/014148 WO2016118638A1 (en) | 2015-01-20 | 2016-01-20 | Anthelmintic compounds, compositions and method of using thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019202773A Division AU2019202773B2 (en) | 2015-01-20 | 2019-04-18 | Anthelmintic Compounds, Compositions And Method Of Using Thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2016209321A1 AU2016209321A1 (en) | 2017-08-17 |
| AU2016209321B2 true AU2016209321B2 (en) | 2019-05-09 |
Family
ID=55299781
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016209321A Ceased AU2016209321B2 (en) | 2015-01-20 | 2016-01-20 | Anthelmintic compounds, compositions and method of using thereof |
| AU2019202773A Ceased AU2019202773B2 (en) | 2015-01-20 | 2019-04-18 | Anthelmintic Compounds, Compositions And Method Of Using Thereof |
| AU2020204400A Abandoned AU2020204400A1 (en) | 2015-01-20 | 2020-06-30 | Anthelmintic compounds, compositions and method of using thereof |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019202773A Ceased AU2019202773B2 (en) | 2015-01-20 | 2019-04-18 | Anthelmintic Compounds, Compositions And Method Of Using Thereof |
| AU2020204400A Abandoned AU2020204400A1 (en) | 2015-01-20 | 2020-06-30 | Anthelmintic compounds, compositions and method of using thereof |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10597364B2 (enExample) |
| EP (1) | EP3247701B1 (enExample) |
| JP (1) | JP6771469B2 (enExample) |
| CN (1) | CN107257793A (enExample) |
| AU (3) | AU2016209321B2 (enExample) |
| BR (1) | BR112017015273A2 (enExample) |
| CA (1) | CA2973873A1 (enExample) |
| ES (1) | ES2907461T3 (enExample) |
| MX (1) | MX379304B (enExample) |
| NZ (1) | NZ734082A (enExample) |
| WO (1) | WO2016118638A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2545964A1 (en) | 2011-07-13 | 2013-01-16 | Phenex Pharmaceuticals AG | Novel FXR (NR1H4) binding and activity modulating compounds |
| CA2968836C (en) | 2016-06-13 | 2025-09-02 | Gilead Sciences, Inc. | FXR MODULATING COMPOUNDS (NR1H4) |
| NZ748641A (en) | 2016-06-13 | 2020-04-24 | Gilead Sciences Inc | Fxr (nr1h4) modulating compounds |
| KR102359707B1 (ko) | 2016-07-20 | 2022-02-09 | 노파르티스 아게 | 아미노피리딘 유도체 및 이의 선택적 alk-2 억제제로서의 용도 |
| ES2982801T3 (es) | 2017-03-28 | 2024-10-17 | Gilead Sciences Inc | Combinaciones terapéuticas para el tratamiento de las enfermedades hepáticas |
| MX2020001425A (es) | 2017-08-04 | 2020-08-06 | Skyhawk Therapeutics Inc | Metodos y composiciones para modular el empalme. |
| TWI793151B (zh) | 2017-08-23 | 2023-02-21 | 瑞士商諾華公司 | 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途 |
| AR116109A1 (es) | 2018-07-10 | 2021-03-31 | Novartis Ag | Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos |
| BR122022012697B1 (pt) | 2018-07-10 | 2023-04-04 | Novartis Ag | Usos de derivados de 3-(5-hidróxi-1-oxoisoindolin-2-il)piperidina-2,6- diona, e kit |
| AR116524A1 (es) * | 2018-10-04 | 2021-05-19 | Elanco Tiergesundheit Ag | Potenciación de tratamiento de helmintos |
| TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
| GB201820626D0 (en) * | 2018-12-18 | 2019-01-30 | Univ Of Canterbury | Conjugates |
| KR102692309B1 (ko) | 2019-01-15 | 2024-08-07 | 길리애드 사이언시즈, 인코포레이티드 | Fxr (nr1h4) 조정 화합물 |
| WO2020150473A2 (en) | 2019-01-18 | 2020-07-23 | Dogma Therapeutics, Inc. | Pcsk9 inhibitors and methods of use thereof |
| BR112021013924A2 (pt) | 2019-01-18 | 2021-09-21 | Astrazeneca Ab | Inibidores de pcsk9 e métodos de uso do mesmo |
| WO2020163248A1 (en) | 2019-02-04 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| WO2020163541A1 (en) | 2019-02-05 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| KR102913697B1 (ko) | 2019-02-05 | 2026-01-15 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
| JP7603594B2 (ja) | 2019-02-06 | 2024-12-20 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| KR102925385B1 (ko) | 2019-02-06 | 2026-02-11 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
| WO2020172075A1 (en) | 2019-02-19 | 2020-08-27 | Gilead Sciences, Inc. | Solid forms of fxr agonists |
| KR20220002890A (ko) * | 2019-03-19 | 2022-01-07 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 구충성 아자-벤조티오펜 및 아자-벤조푸란 화합물 |
| AR119731A1 (es) | 2019-05-17 | 2022-01-05 | Novartis Ag | Inhibidores del inflamasoma nlrp3 |
| US11129829B2 (en) | 2019-06-17 | 2021-09-28 | Skyhawk Therapeutics, Inc. | Methods for modulating splicing |
| CR20220178A (es) | 2019-10-25 | 2022-06-15 | Gilead Sciences Inc | Compuestos moduladores de glp-1r |
| TW202131926A (zh) | 2019-11-22 | 2021-09-01 | 美商英塞特公司 | 包含alk2抑制劑及jak2抑制劑的組合療法 |
| SI4097097T1 (sl) | 2020-01-29 | 2025-04-30 | Gilead Sciences, Inc. | Spojine, ki modulirajo glp-1r |
| KR20230051425A (ko) | 2020-04-07 | 2023-04-18 | 미토브리지, 인크. | Cd38 억제제 |
| IL298219A (en) | 2020-05-15 | 2023-01-01 | Algen Biotechnologies Inc | Certain chemical compositions and methods of use thereof |
| IL298767A (en) | 2020-06-16 | 2023-02-01 | Incyte Corp | ALK2 inhibitors for the treatment of anemia |
| EP4247804A1 (en) | 2020-11-20 | 2023-09-27 | Gilead Sciences, Inc. | Polyheterocyclic glp-1 r modulating compounds |
| US12180197B2 (en) | 2021-03-11 | 2024-12-31 | Gilead Sciences, Inc. | GLP-1R modulating compounds |
| EP4304711A1 (en) | 2021-03-11 | 2024-01-17 | Gilead Sciences, Inc. | Glp-1r modulating compounds |
| US11932630B2 (en) | 2021-04-16 | 2024-03-19 | Novartis Ag | Heteroaryl aminopropanol derivatives |
| LT4271672T (lt) | 2021-04-21 | 2026-03-10 | Gilead Sciences, Inc. | Karboksibenzimidazolo junginiai, moduliuojantys glp-1r |
| UY40374A (es) | 2022-08-03 | 2024-02-15 | Novartis Ag | Inhibidores de inflamasoma nlrp3 |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999031072A1 (en) * | 1997-12-18 | 1999-06-24 | E.I. Du Pont De Nemours And Company | Cyclohexylamine arthropodicides and fungicides |
| EP1403255A1 (en) * | 2001-06-12 | 2004-03-31 | Sumitomo Pharmaceuticals Company, Limited | Rho KINASE INHIBITORS |
| WO2007006389A1 (de) * | 2005-07-14 | 2007-01-18 | Merck Patent Gmbh | Mischung von onium-alkylsulfonaten und onium-alkylsulfiten |
| WO2011044001A1 (en) * | 2009-10-09 | 2011-04-14 | Irm Llc | Compounds and compositions as modulators of gpr119 activity |
| WO2011143495A1 (en) * | 2010-05-13 | 2011-11-17 | Amgen Inc. | Heteroaryloxyheterocyclyl compounds as pde10 inhibitors |
| WO2011143366A1 (en) * | 2010-05-13 | 2011-11-17 | Amgen Inc. | Heteroaryloxycarbocyclyl compounds as pde10 inhibitors |
| WO2013098373A1 (en) * | 2011-12-29 | 2013-07-04 | Boehringer Ingelheim International Gmbh | New azetidine derivatives, pharmaceutical compositions and uses thereof |
| WO2014023723A1 (en) * | 2012-08-08 | 2014-02-13 | Novartis Ag | Subtituted azines as pesticides |
| US20140142114A1 (en) * | 2012-11-20 | 2014-05-22 | Merial Limited | Anthelmintic compounds and compositions and method of using thereof |
| WO2014159690A1 (en) * | 2013-03-12 | 2014-10-02 | Vertex Pharmaceuticals Incorporated | Dna-pk inhibitors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4208254A1 (de) | 1992-03-14 | 1993-09-16 | Hoechst Ag | Substituierte pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel und fungizid |
| AU2001233044A1 (en) | 2000-01-28 | 2001-08-07 | Akkadix Corporation | Methods for killing nematodes and nematode eggs using bis-amino-1,2,4-thiadiazoles |
| EP1689722A2 (en) * | 2003-10-10 | 2006-08-16 | Bayer Pharmaceuticals Corporation | 4-aminopyrimidine derivatives for treatment of hyperproliferative disorders |
| EP1751136B1 (en) * | 2004-05-07 | 2014-07-02 | Amgen Inc. | Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer |
| WO2007063839A1 (ja) * | 2005-11-30 | 2007-06-07 | Shionogi & Co., Ltd. | シクロヘキサン誘導体 |
| TW200938203A (en) | 2007-12-17 | 2009-09-16 | Intervet Int Bv | Anthelmintic agents and their use |
| TW201041868A (en) * | 2009-03-20 | 2010-12-01 | Intervet Int Bv | Anthelmintic agents and their use |
| TW201111358A (en) | 2009-06-18 | 2011-04-01 | Intervet Int Bv | Anthelmintic agents and their use |
| EP2468096A1 (en) | 2010-12-21 | 2012-06-27 | Intervet International BV | Anthelmintic combinations |
| ES2659023T3 (es) | 2013-11-18 | 2018-03-13 | Elanco Tiergesundheit Ag | (Hetero)arilamidas para el control de endoparásitos |
| NZ726874A (en) | 2014-05-19 | 2018-03-23 | Merial Inc | Anthelmintic compounds |
-
2016
- 2016-01-20 ES ES16702865T patent/ES2907461T3/es active Active
- 2016-01-20 JP JP2017538327A patent/JP6771469B2/ja not_active Expired - Fee Related
- 2016-01-20 CA CA2973873A patent/CA2973873A1/en not_active Abandoned
- 2016-01-20 EP EP16702865.3A patent/EP3247701B1/en active Active
- 2016-01-20 MX MX2017009408A patent/MX379304B/es unknown
- 2016-01-20 US US15/544,837 patent/US10597364B2/en active Active
- 2016-01-20 NZ NZ734082A patent/NZ734082A/en not_active IP Right Cessation
- 2016-01-20 WO PCT/US2016/014148 patent/WO2016118638A1/en not_active Ceased
- 2016-01-20 CN CN201680010899.2A patent/CN107257793A/zh active Pending
- 2016-01-20 AU AU2016209321A patent/AU2016209321B2/en not_active Ceased
- 2016-01-20 BR BR112017015273-8A patent/BR112017015273A2/pt active Search and Examination
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2019
- 2019-04-18 AU AU2019202773A patent/AU2019202773B2/en not_active Ceased
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- 2020-06-30 AU AU2020204400A patent/AU2020204400A1/en not_active Abandoned
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999031072A1 (en) * | 1997-12-18 | 1999-06-24 | E.I. Du Pont De Nemours And Company | Cyclohexylamine arthropodicides and fungicides |
| EP1403255A1 (en) * | 2001-06-12 | 2004-03-31 | Sumitomo Pharmaceuticals Company, Limited | Rho KINASE INHIBITORS |
| WO2007006389A1 (de) * | 2005-07-14 | 2007-01-18 | Merck Patent Gmbh | Mischung von onium-alkylsulfonaten und onium-alkylsulfiten |
| WO2011044001A1 (en) * | 2009-10-09 | 2011-04-14 | Irm Llc | Compounds and compositions as modulators of gpr119 activity |
| WO2011143495A1 (en) * | 2010-05-13 | 2011-11-17 | Amgen Inc. | Heteroaryloxyheterocyclyl compounds as pde10 inhibitors |
| WO2011143366A1 (en) * | 2010-05-13 | 2011-11-17 | Amgen Inc. | Heteroaryloxycarbocyclyl compounds as pde10 inhibitors |
| WO2013098373A1 (en) * | 2011-12-29 | 2013-07-04 | Boehringer Ingelheim International Gmbh | New azetidine derivatives, pharmaceutical compositions and uses thereof |
| WO2014023723A1 (en) * | 2012-08-08 | 2014-02-13 | Novartis Ag | Subtituted azines as pesticides |
| US20140142114A1 (en) * | 2012-11-20 | 2014-05-22 | Merial Limited | Anthelmintic compounds and compositions and method of using thereof |
| WO2014159690A1 (en) * | 2013-03-12 | 2014-10-02 | Vertex Pharmaceuticals Incorporated | Dna-pk inhibitors |
Non-Patent Citations (1)
| Title |
|---|
| CAS RN: 1350249-77-2; Entered STN 07 December 2011; N-[cis-4-[[5-(4-methyl-1-piperazinyl)-1H-indazol-4-yl]oxy]cyclohexyl]-benzenamine * |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2017009408A (es) | 2017-10-02 |
| EP3247701B1 (en) | 2021-09-22 |
| AU2020204400A1 (en) | 2020-07-30 |
| ES2907461T3 (es) | 2022-04-25 |
| US20180009754A1 (en) | 2018-01-11 |
| JP6771469B2 (ja) | 2020-10-21 |
| JP2018502877A (ja) | 2018-02-01 |
| WO2016118638A1 (en) | 2016-07-28 |
| MX379304B (es) | 2025-03-11 |
| US10597364B2 (en) | 2020-03-24 |
| AU2019202773A1 (en) | 2019-05-16 |
| CA2973873A1 (en) | 2016-07-28 |
| EP3247701A1 (en) | 2017-11-29 |
| NZ734082A (en) | 2019-01-25 |
| AU2016209321A1 (en) | 2017-08-17 |
| AU2019202773B2 (en) | 2020-07-02 |
| BR112017015273A2 (pt) | 2018-01-09 |
| CN107257793A (zh) | 2017-10-17 |
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| Date | Code | Title | Description |
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| PC1 | Assignment before grant (sect. 113) |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |