US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
JPS55113334A
(en)
|
1979-02-23 |
1980-09-01 |
Hitachi Ltd |
Manufacture of passivation film
|
US4332785A
(en)
|
1980-04-09 |
1982-06-01 |
University Patents, Inc. |
Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein
|
US4447547A
(en)
|
1980-04-09 |
1984-05-08 |
University Patents, Inc. |
Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein
|
US4626507A
(en)
|
1980-09-25 |
1986-12-02 |
The Salk Institute For Biological Studies |
Hybridomas producing monoclonal antibodies specific for a human cell surface glycoprotein
|
US4434156A
(en)
|
1981-10-26 |
1984-02-28 |
The Salk Institute For Biological Studies |
Monoclonal antibodies specific for the human transferrin receptor glycoprotein
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4545985A
(en)
|
1984-01-26 |
1985-10-08 |
The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services |
Pseudomonas exotoxin conjugate immunotoxins
|
JPS6210017A
(en)
|
1985-07-04 |
1987-01-19 |
Mochida Pharmaceut Co Ltd |
Purification of transferrine receptor
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
US4956453A
(en)
|
1985-12-06 |
1990-09-11 |
Cetus Corporation |
Anti-human ovarian cancer immunotoxins and methods of use thereof
|
US4801575A
(en)
|
1986-07-30 |
1989-01-31 |
The Regents Of The University Of California |
Chimeric peptides for neuropeptide delivery through the blood-brain barrier
|
US4902505A
(en)
|
1986-07-30 |
1990-02-20 |
Alkermes |
Chimeric peptides for neuropeptide delivery through the blood-brain barrier
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
US4892827A
(en)
*
|
1986-09-24 |
1990-01-09 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
|
CA1329156C
(en)
|
1987-03-11 |
1994-05-03 |
Ian Farquhar Campbell Mckenzie |
Immunoglobulin conjugates
|
US5208021A
(en)
|
1987-10-05 |
1993-05-04 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of preparing diphtheria immunotoxins
|
US5728383A
(en)
|
1987-10-05 |
1998-03-17 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Treatment of tumors of the central nervous system with immunotoxins
|
US5352447A
(en)
|
1987-10-05 |
1994-10-04 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Immunotoxins for treatment of intracranial lesions and as adjunct to chemotherapy
|
US5792458A
(en)
|
1987-10-05 |
1998-08-11 |
The United States Of America As Represented By The Department Of Health And Human Services |
Mutant diphtheria toxin conjugates
|
US5231000A
(en)
*
|
1987-10-08 |
1993-07-27 |
The Mclean Hospital |
Antibodies to A4 amyloid peptide
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
US5217713A
(en)
|
1988-12-27 |
1993-06-08 |
Takeda Chemical Industries, Ltd. |
Cytotoxic bispecific monoclonal antibody, its production and use
|
CA2006408A1
(en)
|
1988-12-27 |
1990-06-27 |
Susumu Iwasa |
Bispecific monoclonal antibody, its production and use
|
CA2011099A1
(en)
|
1989-04-19 |
1990-10-19 |
Stephen C. Wardlaw |
Determination of lymphocyte reactivity to specific antigens in blood
|
US5292869A
(en)
|
1989-04-27 |
1994-03-08 |
The Board Of Governors Of The University |
Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same
|
US5141743A
(en)
|
1989-04-27 |
1992-08-25 |
University Technologies International, Inc. |
Method for isolating and purifying transferrin and lactoferrin receptor proteins and vaccines containing the same
|
US5182107A
(en)
|
1989-09-07 |
1993-01-26 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates
|
US5977307A
(en)
|
1989-09-07 |
1999-11-02 |
Alkermes, Inc. |
Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins
|
US5672683A
(en)
|
1989-09-07 |
1997-09-30 |
Alkermes, Inc. |
Transferrin neuropharmaceutical agent fusion protein
|
US5154924A
(en)
|
1989-09-07 |
1992-10-13 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical agent conjugates
|
US5527527A
(en)
|
1989-09-07 |
1996-06-18 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical agent conjugates
|
US6329508B1
(en)
|
1989-09-07 |
2001-12-11 |
Alkermes, Inc. |
Transferrin receptor reactive chimeric antibodies
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
CA2081368A1
(en)
|
1990-03-27 |
1991-09-28 |
Ian S. Trowbridge |
Method for inhibiting cell growth and compositions useful therefor
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
WO1992003467A1
(en)
|
1990-08-23 |
1992-03-05 |
The University Of North Carolina Of Chapel Hill |
Transferrin binding proteins from neisseria gonorrhoeae and neisseria meningitidis
|
US5912336A
(en)
|
1990-08-23 |
1999-06-15 |
University Of North Carolina At Chapel Hill |
Isolated nucleic acid molecules encoding transferrin binding proteins from Neisseria gonorrhoeae and Neisseria meningitidis
|
JPH04187096A
(en)
|
1990-11-20 |
1992-07-03 |
Takeda Chem Ind Ltd |
Hybrid monoclonal antibody having double specificity
|
US6099842A
(en)
|
1990-12-03 |
2000-08-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin
|
DE4110409C2
(en)
|
1991-03-29 |
1999-05-27 |
Boehringer Ingelheim Int |
New protein-polycation conjugates
|
US6287792B1
(en)
|
1991-06-17 |
2001-09-11 |
The Regents Of The University Of California |
Drug delivery of antisense oligonucleotides and peptides to tissues in vivo and to cells using avidin-biotin technology
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
SK285960B6
(en)
|
1991-07-25 |
2007-12-06 |
Biogen Idec Inc. |
Recombinant antibodies for human therapy
|
MX9204374A
(en)
|
1991-07-25 |
1993-03-01 |
Idec Pharma Corp |
RECOMBINANT ANTIBODY AND METHOD FOR ITS PRODUCTION.
|
ES2136092T3
(en)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
PROCEDURES FOR THE PRODUCTION OF HUMANIZED ANTIBODIES.
|
US5254342A
(en)
|
1991-09-30 |
1993-10-19 |
University Of Southern California |
Compositions and methods for enhanced transepithelial and transendothelial transport or active agents
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
JPH07509444A
(en)
|
1991-11-26 |
1995-10-19 |
アルカーメス・インコーポレーテツド |
Method for producing transferrin receptor-specific antibody-nerve drug or diagnostic drug complex
|
WO1993016177A1
(en)
|
1992-02-11 |
1993-08-19 |
Cell Genesys, Inc. |
Homogenotization of gene-targeting events
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
US5648469A
(en)
|
1992-04-20 |
1997-07-15 |
The Salk Institute For Biological Studies |
Monoclonal antibodies reactive with transferrin receptor cytoplasmic domain
|
FR2692592B1
(en)
|
1992-06-19 |
1995-03-31 |
Pasteur Merieux Serums Vacc |
DNA fragments encoding the Neisseria meningitidis transferrin receptor subunits and methods of expressing them.
|
EP0652775B1
(en)
|
1992-07-27 |
2000-04-19 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Targeting of liposomes to the blood-brain barrier
|
AU705998B2
(en)
|
1993-11-08 |
1999-06-03 |
Connaught Laboratories Limited |
Haemophilus transferrin receptor genes
|
US6361779B1
(en)
|
1993-11-08 |
2002-03-26 |
Aventis Pasteur Limited |
Transferrin receptor genes
|
JPH09506262A
(en)
|
1993-12-08 |
1997-06-24 |
ジェンザイム・コーポレイション |
Method for producing specific antibody
|
IL112372A
(en)
|
1994-02-07 |
2001-08-26 |
Res Dev Foundation |
Non-viral vector for the delivery of genetic information to cells
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US6015555A
(en)
|
1995-05-19 |
2000-01-18 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates
|
US5817789A
(en)
|
1995-06-06 |
1998-10-06 |
Transkaryotic Therapies, Inc. |
Chimeric proteins for use in transport of a selected substance into cells
|
JP3973169B2
(en)
|
1995-09-26 |
2007-09-12 |
栄研化学株式会社 |
Transferrin-transferrin receptor complex measuring reagent and measuring method
|
US6290970B1
(en)
|
1995-10-11 |
2001-09-18 |
Aventis Pasteur Limited |
Transferrin receptor protein of Moraxella
|
US6497881B1
(en)
|
1995-11-30 |
2002-12-24 |
New York University |
High efficiency tissue specific compound delivery system using streptavidin-protein a fusion protein
|
JP4512882B2
(en)
|
1996-02-09 |
2010-07-28 |
チェング ピー―ワン |
Delivery of bioactive molecules facilitated by receptor ligands
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
US6090576A
(en)
|
1996-03-08 |
2000-07-18 |
Connaught Laboratories Limited |
DNA encoding a transferrin receptor of Moraxella
|
US6440701B1
(en)
|
1996-03-08 |
2002-08-27 |
Aventis Pasteur Limited |
Transferrin receptor genes of Moraxella
|
AU5451598A
(en)
|
1996-11-22 |
1998-06-10 |
Regents Of The University Of California, The |
Transport of liposomes across the blood-brain barrier
|
JPH10245400A
(en)
|
1997-02-28 |
1998-09-14 |
Eiken Chem Co Ltd |
Stabilization of transferrin receptor
|
AU757627B2
(en)
|
1997-06-24 |
2003-02-27 |
Genentech Inc. |
Methods and compositions for galactosylated glycoproteins
|
ATE419009T1
(en)
|
1997-10-31 |
2009-01-15 |
Genentech Inc |
METHODS AND COMPOSITIONS CONSISTING OF GLYCOPROTEIN GLYCOFORMS
|
WO1999042127A2
(en)
|
1998-02-24 |
1999-08-26 |
Receptron, Inc. |
Receptor derived peptides as modulators of receptor activity
|
DE69937291T2
(en)
|
1998-04-02 |
2008-07-10 |
Genentech, Inc., South San Francisco |
ANTIBODY VARIANTS AND FRAGMENTS THEREOF
|
DK2180007T4
(en)
|
1998-04-20 |
2017-11-27 |
Roche Glycart Ag |
Glycosylation technique for antibodies to enhance antibody-dependent cell cytotoxicity
|
US6891028B1
(en)
|
1998-11-06 |
2005-05-10 |
Cedars-Sinai Medical Center |
Nucleic acids encoding transferrin receptor-like proteins
|
CA2350415A1
(en)
|
1998-11-18 |
2000-05-25 |
Incyte Pharmaceuticals, Inc. |
Inflammation-associated genes
|
AU1628800A
(en)
|
1998-11-19 |
2000-06-05 |
Georgetown University |
Systemic viral/ligand gene delivery system and gene therapy
|
KR20060067983A
(en)
|
1999-01-15 |
2006-06-20 |
제넨테크, 인크. |
Polypeptide variants with altered effector function
|
AU3703100A
(en)
|
1999-02-22 |
2000-09-14 |
Georgetown University |
Antibody fragment-targeted immunoliposomes for systemic gene delivery
|
US7780882B2
(en)
|
1999-02-22 |
2010-08-24 |
Georgetown University |
Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent
|
GB9908195D0
(en)
|
1999-04-09 |
1999-06-02 |
Microbiological Res Authority |
Treatment of intracellular infection
|
US7241449B1
(en)
|
1999-04-12 |
2007-07-10 |
Aventis Pasteur Limited |
Transferrin receptor genes of moraxella
|
US6511967B1
(en)
|
1999-04-23 |
2003-01-28 |
The General Hospital Corporation |
Use of an internalizing transferrin receptor to image transgene expression
|
DK1409654T3
(en)
|
1999-06-16 |
2008-12-08 |
Boston Biomedical Res Inst |
Immunological control of beta-amyloid levels in vivo
|
US20040146516A1
(en)
|
1999-06-17 |
2004-07-29 |
Utah Ventures Ii L.P. |
Lumen-exposed molecules and methods for targeted delivery
|
AU6607100A
(en)
|
1999-07-23 |
2001-02-13 |
Regents Of The University Of California, The |
Anti-growth factor receptor avidin fusion proteins as universal vectors for drugdelivery
|
WO2001044300A2
(en)
|
1999-12-13 |
2001-06-21 |
Cambridge Antibody Technology Limited |
Brain specific binding members
|
WO2001074399A1
(en)
|
2000-03-30 |
2001-10-11 |
Ajinomoto Co., Inc. |
Drugs retained in target tissue over long time
|
EP1272647B1
(en)
|
2000-04-11 |
2014-11-12 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
US20020136732A1
(en)
|
2000-04-23 |
2002-09-26 |
Houston L. L. |
Compositions comprising carriers and transportable complexes
|
US6372250B1
(en)
|
2000-04-25 |
2002-04-16 |
The Regents Of The University Of California |
Non-invasive gene targeting to the brain
|
GB0027328D0
(en)
|
2000-06-23 |
2000-12-27 |
Aventis Pharma Inc |
Bioengineered vehicles for targeted nucleic acid delivery
|
WO2002007783A2
(en)
|
2000-07-20 |
2002-01-31 |
Regents Of The University Of Minnesota |
Radiolabeled immunotoxins
|
AU2001290638C1
(en)
|
2000-09-06 |
2009-04-30 |
Aventis Pharma S.A. |
Methods and compositions for diseases associated with amyloidosis
|
JP2002095476A
(en)
|
2000-09-20 |
2002-04-02 |
Eisai Co Ltd |
Method for transferring gene via transferrin receptor
|
US6743893B2
(en)
|
2000-11-30 |
2004-06-01 |
The Uab Research Foundation |
Receptor-mediated uptake of peptides that bind the human transferrin receptor
|
US20030165853A1
(en)
|
2000-12-04 |
2003-09-04 |
The Regents Of The University Of California Office Of Technology Transfer |
Antisense imaging of gene expression of the brain in vivo
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
DE10121982B4
(en)
|
2001-05-05 |
2008-01-24 |
Lts Lohmann Therapie-Systeme Ag |
Nanoparticles of protein with coupled apolipoprotein E to overcome the blood-brain barrier and process for their preparation
|
WO2002094191A2
(en)
|
2001-05-23 |
2002-11-28 |
New York University |
Detection of alzheimer's amyloid by magnetic resonance imaging
|
US20100081792A1
(en)
|
2001-06-28 |
2010-04-01 |
Smithkline Beecham Corporation |
Ligand
|
NZ592087A
(en)
|
2001-08-03 |
2012-11-30 |
Roche Glycart Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
US20030226155A1
(en)
|
2001-08-30 |
2003-12-04 |
Biorexis Pharmaceutical Corporation |
Modified transferrin-antibody fusion proteins
|
US7176278B2
(en)
|
2001-08-30 |
2007-02-13 |
Biorexis Technology, Inc. |
Modified transferrin fusion proteins
|
EP1427750B1
(en)
|
2001-08-30 |
2010-12-08 |
Biorexis Pharmaceutical Corporation |
Modified transferrin fusion proteins
|
AU2002337935B2
(en)
|
2001-10-25 |
2008-05-01 |
Genentech, Inc. |
Glycoprotein compositions
|
US20040093621A1
(en)
|
2001-12-25 |
2004-05-13 |
Kyowa Hakko Kogyo Co., Ltd |
Antibody composition which specifically binds to CD20
|
US7998704B2
(en)
|
2002-03-07 |
2011-08-16 |
Carnegie Mellon University |
Methods for magnetic resonance imaging
|
DE60327927D1
(en)
|
2002-03-07 |
2009-07-23 |
Univ Carnegie Mellon |
CONTRASTING AGENTS FOR MAGNETIC RESONANCE TOMOGRAPHY AND CORRESPONDING METHODS
|
US20050249721A1
(en)
|
2002-04-02 |
2005-11-10 |
Houston L L |
Compositions and methods for targeted biological delivery of molecular carriers
|
AU2003270010A1
(en)
|
2002-08-30 |
2004-03-19 |
Biorexis Pharmaceutical Corporation |
Transferrin fusion protein libraries
|
AU2003270009A1
(en)
|
2002-08-30 |
2004-03-19 |
Biorexis Pharmaceutical Corporation |
Oral delivery of modified transferrin fusion proteins
|
ES2347144T3
(en)
|
2002-08-30 |
2010-10-26 |
Biorexis Pharmaceutical Corporation |
FUSION PROTEINS OF THE MODIFIED TRANSFERRINE THAT INCLUDE DOMINOS AINO OR CARBOXILO OF TRANSFERRINA DUPLICATED.
|
BRPI0316092B8
(en)
|
2002-11-08 |
2021-05-25 |
Ablynx Nv |
single domain antibodies directed against tumor necrosis factor alpha and uses for them
|
US20050142141A1
(en)
|
2002-11-27 |
2005-06-30 |
Pardridge William M. |
Delivery of enzymes to the brain
|
US20040102369A1
(en)
|
2002-11-27 |
2004-05-27 |
The Regents Of The University Of California |
Transport of basic fibroblast growth factor across the blood brain barrier
|
JP4995423B2
(en)
|
2002-12-03 |
2012-08-08 |
ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート |
Artificial low density lipoprotein carrier for transporting substances across the blood-brain barrier
|
CA2512717A1
(en)
|
2003-01-09 |
2004-07-29 |
Arizeke Pharmaceuticals Inc. |
Compositions and methods for targeted biological delivery of molecular carriers
|
JP4187096B2
(en)
|
2003-01-15 |
2008-11-26 |
独立行政法人科学技術振興機構 |
Three-dimensional photonic crystal manufacturing method
|
NZ541760A
(en)
*
|
2003-02-10 |
2008-09-26 |
To Bbb Holding B V |
Differentially expressed nucleic acids in the blood-brain barrier under inflammatory conditions
|
CN1788017B
(en)
*
|
2003-02-10 |
2013-04-24 |
to-BBB控股股份有限公司 |
Differentially expressed nucleic acids in the blood-brain barrier under inflammatory conditions
|
EP1626981A4
(en)
|
2003-03-04 |
2006-11-22 |
Biorexis Pharmaceutical Corp |
Dipeptidyl-peptidase protected proteins
|
AU2003286870A1
(en)
|
2003-06-05 |
2005-01-04 |
Salk Institute For Biological Studies |
Targeting polypeptides to the central nervous system
|
CA2531228A1
(en)
|
2003-08-04 |
2005-02-17 |
Applied Research Systems Ars Holding N.V. |
Novel therapeutic fusion proteins
|
US20050042298A1
(en)
|
2003-08-20 |
2005-02-24 |
Pardridge William M. |
Immunonanoparticles
|
JP2007512001A
(en)
|
2003-08-28 |
2007-05-17 |
バイオレクシス ファーマシューティカル コーポレイション |
EPO mimetic peptides and fusion proteins
|
WO2005025511A2
(en)
|
2003-09-10 |
2005-03-24 |
Cedars-Sinai Medical Center |
Potassium channel mediated delivery of agents through the blood-brain barrier
|
SG10202008722QA
(en)
|
2003-11-05 |
2020-10-29 |
Roche Glycart Ag |
Cd20 antibodies with increased fc receptor binding affinity and effector function
|
US20050202075A1
(en)
|
2004-03-12 |
2005-09-15 |
Pardridge William M. |
Delivery of genes encoding short hairpin RNA using receptor-specific nanocontainers
|
WO2005094364A2
(en)
|
2004-03-31 |
2005-10-13 |
Chimeric Technologies, Inc. |
Iga antibody protein as a cytotoxic drug
|
JP4756032B2
(en)
|
2004-03-31 |
2011-08-24 |
アトナーゲン アクチエンゲゼルシャフト |
Monoclonal antibody with specificity for fetal red blood cells
|
WO2005111082A1
(en)
|
2004-04-30 |
2005-11-24 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Anti-tfr antibody.
|
CA2572453A1
(en)
|
2004-06-02 |
2005-12-15 |
Sidney Kimmel Cancer Center |
Imaging and therapeutic agents targeting proteins expressed on endothelial cell surface
|
CA2569692C
(en)
|
2004-06-07 |
2015-07-21 |
Raven Biotechnologies, Inc. |
Transferrin receptor antibodies
|
US20060018897A1
(en)
|
2004-06-28 |
2006-01-26 |
Transtarget Inc. |
Bispecific antibodies
|
WO2006088491A2
(en)
|
2004-06-29 |
2006-08-24 |
Massachusetts Institute Of Technology |
Methods and compositions related to the modulation of intercellular junctions
|
JP2008515808A
(en)
|
2004-10-04 |
2008-05-15 |
トリニティ バイオシステムズ インコーポレーテッド |
Methods and compositions for needle-free polymer delivery
|
JP2008531059A
(en)
|
2005-03-04 |
2008-08-14 |
バイオレクシス ファーマシューティカル コーポレーション |
Modified transferrin fusion protein
|
WO2006126208A2
(en)
|
2005-05-26 |
2006-11-30 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Compositions and methods using same for delivering agents into a target organ protected by a blood barrier
|
JP2005321411A
(en)
|
2005-06-10 |
2005-11-17 |
Eiken Chem Co Ltd |
Reagent and method for measuring transferrin-transferrin receptor complex
|
US7736647B2
(en)
|
2005-06-15 |
2010-06-15 |
Monoclonal Antibodies Therapeutics |
Anti-CD71 monoclonal antibodies and uses thereof for treating malignant tumor cells
|
CA2611054C
(en)
|
2005-06-17 |
2017-05-09 |
National Research Council Of Canada |
Novel a.beta.-binding polypeptides and derivatives and uses thereof
|
SI1928503T1
(en)
|
2005-08-24 |
2012-11-30 |
Immunogen Inc |
Process for preparing maytansinoid antibody conjugates
|
WO2007027559A2
(en)
|
2005-08-29 |
2007-03-08 |
Shashoua Victor E |
Neuroprotective and neurorestorative methods and compositions
|
US8053569B2
(en)
|
2005-10-07 |
2011-11-08 |
Armagen Technologies, Inc. |
Nucleic acids encoding and methods of producing fusion proteins
|
US8124095B2
(en)
|
2005-10-07 |
2012-02-28 |
Armagen Technologies, Inc. |
Fusion proteins for delivery of erythropoietin to the CNS
|
WO2007047504A2
(en)
|
2005-10-14 |
2007-04-26 |
Biorexis Pharmaceutical Corporation |
Natriuretic peptide modified transferrin fusion proteins
|
EP1971367A4
(en)
|
2005-12-05 |
2010-04-07 |
Trinity Biosystems Inc |
Methods and compositions for needleless delivery of binding partners
|
WO2007067596A2
(en)
|
2005-12-05 |
2007-06-14 |
Trinity Biosystems, Inc. |
Methods and compositions for needleless delivery of antibodies
|
KR20150098683A
(en)
|
2005-12-12 |
2015-08-28 |
에이씨 이뮨 에스.에이. |
A beta 1-42 specific monoclonal antibodies with therapeutic properties
|
WO2007103288A2
(en)
|
2006-03-02 |
2007-09-13 |
Seattle Genetics, Inc. |
Engineered antibody drug conjugates
|
WO2007112451A2
(en)
|
2006-03-28 |
2007-10-04 |
University Of Washington |
Covalent conjugates between endoperoxides and transferrin and lactoferrin receptor-binding agents
|
CN101415729B
(en)
*
|
2006-03-30 |
2013-09-04 |
葛兰素集团有限公司 |
Antibodies against amyloid-beta peptide
|
US8748567B2
(en)
|
2006-05-22 |
2014-06-10 |
Children's Medical Center Corporation |
Method for delivery across the blood brain barrier
|
US7744879B2
(en)
*
|
2006-06-07 |
2010-06-29 |
Wisconsin Alumni Research Foundation |
Blood-brain barrier targeting antibodies
|
SG173385A1
(en)
|
2006-07-14 |
2011-08-29 |
Ac Immune S A Ch |
Humanized antibody against amyloid beta
|
CA2672147A1
(en)
|
2006-07-27 |
2008-01-31 |
University Of Virginia Patent Foundation |
System and method for intracranial implantation of therapeutic or diagnostic agents
|
US20090092660A1
(en)
|
2006-08-09 |
2009-04-09 |
Trinity Biosystems, Inc. |
Methods and compositions for needleless delivery of particles
|
WO2008021412A2
(en)
|
2006-08-14 |
2008-02-21 |
Biorexis Pharmaceutical Corporation |
Interferon beta and transferrin fusion proteins
|
US8759297B2
(en)
*
|
2006-08-18 |
2014-06-24 |
Armagen Technologies, Inc. |
Genetically encoded multifunctional compositions bidirectionally transported between peripheral blood and the cns
|
WO2008027236A2
(en)
|
2006-08-30 |
2008-03-06 |
Genentech, Inc. |
Multispecific antibodies
|
WO2008033924A2
(en)
|
2006-09-12 |
2008-03-20 |
Board Of Regents Of The University Of Nebraska |
Methods and compositions for targeted delivery of therapeutic agents
|
WO2008033395A2
(en)
|
2006-09-14 |
2008-03-20 |
Biorexis Pharmaceutical Corporation |
Melanocortin and transferrin fusion proteins
|
WO2008050133A2
(en)
|
2006-10-27 |
2008-05-02 |
Zapaloid Limited |
Inhibition of beta-amyloid aggregation
|
CN101245107B
(en)
*
|
2007-02-14 |
2010-10-13 |
中国人民解放军军事医学科学院生物工程研究所 |
Antihuman transferrin acceptor human source antibody and uses thereof
|
WO2008106524A1
(en)
|
2007-02-27 |
2008-09-04 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Use of histone deacetylase inhibitors for the treatment of central nervous system metastases
|
EP2125024B1
(en)
|
2007-03-23 |
2013-02-13 |
TO-BBB Holding B.V. |
Targeted intracellular delivery of antiviral agents
|
EP1975178A1
(en)
|
2007-03-30 |
2008-10-01 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Transcytotic modular antibody
|
AU2008257419B2
(en)
|
2007-05-23 |
2013-10-24 |
The Trustees Of The University Of Pennsylvania |
Targeted carriers for intracellular drug delivery
|
CL2008001742A1
(en)
|
2007-06-12 |
2008-11-21 |
Ac Immune Sa |
Monoclonal antibody that recognizes a conformational epitope and binds to polymeric soluble amyloid peptides and oligomeric amyloid peptides; polynucleotide that encodes it; composition that includes it; and its use to treat diseases associated with amyloid proteins.
|
RU2567151C2
(en)
|
2007-06-12 |
2015-11-10 |
Ац Иммуне С.А. |
Humanised antibodies to amyloid beta
|
GB0711424D0
(en)
|
2007-06-13 |
2007-07-25 |
Novozymes Delta Ltd |
Recombinant transferrin mutants
|
US7973019B1
(en)
|
2007-10-03 |
2011-07-05 |
Alcon Research, Ltd. |
Transferrin/transferrin receptor-mediated siRNA delivery
|
GB0725065D0
(en)
|
2007-12-21 |
2008-01-30 |
Got A Gene Ab |
Method
|
HUE028536T2
(en)
|
2008-01-07 |
2016-12-28 |
Amgen Inc |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
US8420620B2
(en)
|
2008-01-24 |
2013-04-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Induced internalization of surface receptors
|
AU2009231439A1
(en)
|
2008-03-31 |
2009-10-08 |
Glaxo Group Limited |
Drug fusions and conjugates
|
US20110250199A1
(en)
|
2008-06-04 |
2011-10-13 |
The Government of the United States of America as represented by the Secretary of the Department.... |
Immunotoxins and uses thereof
|
US7989597B2
(en)
*
|
2008-06-20 |
2011-08-02 |
Oklahoma Medical Research Foundation |
Immunogenic memapsin 2 β-secretase peptides and methods of use
|
US20100077498A1
(en)
|
2008-09-11 |
2010-03-25 |
Pardridge William M |
Compositions and methods for blood-brain barrier delivery in the mouse
|
US8946165B2
(en)
|
2008-09-29 |
2015-02-03 |
The Regents Of The University Of California |
Compounds for reversing and inhibiting protein aggregation, and methods for making and using them
|
US20100098693A1
(en)
|
2008-10-07 |
2010-04-22 |
Pardridge William M |
Compositions and methods for blood-brain barrier delivery of organophosphatases
|
CN102482347B
(en)
|
2009-01-12 |
2017-04-26 |
希托马克斯医疗有限责任公司 |
Modified antibody compositions, and methods of making and using thereof
|
US8530629B2
(en)
*
|
2009-01-30 |
2013-09-10 |
Ab Biosciences, Inc. |
Lowered affinity antibodies and uses therefor
|
CA2748889A1
(en)
|
2009-03-18 |
2010-09-23 |
Armagen Technologies, Inc. |
Compositions and methods for blood-brain barrier delivery of igg-decoy receptor fusion proteins
|
US20120156138A1
(en)
|
2009-04-14 |
2012-06-21 |
Smith Larry J |
Methods and Compositions for the Treatment of Medical Conditions Involving Cellular Reprogramming
|
WO2010146058A1
(en)
*
|
2009-06-15 |
2010-12-23 |
Vib Vzw |
Bace1 inhibitory antibodies
|
CA2768598A1
(en)
|
2009-07-22 |
2011-01-27 |
Cenix Bioscience Gmbh |
Delivery system and conjugates for compound delivery via naturally occurring intracellular transport routes
|
TW201109438A
(en)
*
|
2009-07-29 |
2011-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
US9149544B2
(en)
|
2009-11-06 |
2015-10-06 |
The Penn State Research Foundation |
Bioconjugation of calcium phosphosilicate nanoparticles for selective targeting of cells in vivo
|
FR2953841B1
(en)
|
2009-12-16 |
2011-12-30 |
Centre Nat Rech Scient |
ANTIBODIES AGAINST THE TRANSFERRIN RECEPTOR AND THEIR USES FOR THE IMMUNOTHERAPY OF TUMORS THAT DEPEND ON IRON
|
ME02505B
(en)
|
2009-12-29 |
2017-02-20 |
Aptevo Res & Development Llc |
Heterodimer binding proteins and uses thereof
|
WO2011130164A2
(en)
|
2010-04-13 |
2011-10-20 |
The Regents Of The University Of California |
Unconjugated anti-tfr antibodies and compositions thereof for the treatment of cancer
|
FR2959416B1
(en)
|
2010-05-03 |
2012-06-22 |
Monoclonal Antibodies Therapeutics Mat Biopharma |
USE OF ANTI-CD71 ANTIBODIES FOR THE PREPARATION OF A MEDICINAL PRODUCT
|
PT2646470T
(en)
|
2010-11-30 |
2017-05-03 |
Hoffmann La Roche |
Low affinity anti-transferrin receptor antibodies and their use to transfer therapeutic scfv across the blood brain barrier
|
JP6210017B2
(en)
|
2014-04-17 |
2017-10-11 |
マツダ株式会社 |
Automatic transmission
|