AU2015306643B2 - Soluble epoxide hydrolase inhibitors and uses thereof - Google Patents
Soluble epoxide hydrolase inhibitors and uses thereof Download PDFInfo
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- AU2015306643B2 AU2015306643B2 AU2015306643A AU2015306643A AU2015306643B2 AU 2015306643 B2 AU2015306643 B2 AU 2015306643B2 AU 2015306643 A AU2015306643 A AU 2015306643A AU 2015306643 A AU2015306643 A AU 2015306643A AU 2015306643 B2 AU2015306643 B2 AU 2015306643B2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2020207828A AU2020207828A1 (en) | 2014-08-28 | 2020-07-22 | Soluble epoxide hydrolase inhibitors and uses thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462043275P | 2014-08-28 | 2014-08-28 | |
| US62/043,275 | 2014-08-28 | ||
| PCT/US2015/046878 WO2016033150A1 (en) | 2014-08-28 | 2015-08-26 | Soluble epoxide hydrolase inhibitors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020207828A Division AU2020207828A1 (en) | 2014-08-28 | 2020-07-22 | Soluble epoxide hydrolase inhibitors and uses thereof |
Publications (2)
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|---|---|
| AU2015306643A1 AU2015306643A1 (en) | 2017-03-16 |
| AU2015306643B2 true AU2015306643B2 (en) | 2020-05-07 |
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| AU2015306643A Ceased AU2015306643B2 (en) | 2014-08-28 | 2015-08-26 | Soluble epoxide hydrolase inhibitors and uses thereof |
| AU2020207828A Abandoned AU2020207828A1 (en) | 2014-08-28 | 2020-07-22 | Soluble epoxide hydrolase inhibitors and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020207828A Abandoned AU2020207828A1 (en) | 2014-08-28 | 2020-07-22 | Soluble epoxide hydrolase inhibitors and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10081616B2 (enExample) |
| EP (1) | EP3186228A4 (enExample) |
| JP (1) | JP2017525777A (enExample) |
| CN (2) | CN107074771B (enExample) |
| AU (2) | AU2015306643B2 (enExample) |
| CA (1) | CA2958881A1 (enExample) |
| MA (1) | MA40538A (enExample) |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017525777A (ja) * | 2014-08-28 | 2017-09-07 | エックス−ケム，インコーポレーテッド | 可溶性エポキシドヒドロラーゼ阻害剤及びこれらの使用 |
| EP3600266B1 (en) * | 2017-03-30 | 2022-07-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Pharmaceutical compositions for use in the treatment of cardiovascular calcification |
| US20230071934A1 (en) * | 2019-12-18 | 2023-03-09 | Intra-Cellular Therapies, Inc. | Novel uses |
| WO2024105225A1 (en) | 2022-11-18 | 2024-05-23 | Universitat De Barcelona | Synergistic combinations of a sigma receptor 1 (s1r) antagonist and a soluble epoxide hydrolase inhibitor (sehi) and their use in the treatment of pain |
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- 2015-08-26 EP EP15837061.9A patent/EP3186228A4/en not_active Withdrawn
- 2015-08-26 AU AU2015306643A patent/AU2015306643B2/en not_active Ceased
- 2015-08-26 CN CN201580046202.2A patent/CN107074771B/zh not_active Expired - Fee Related
- 2015-08-26 MA MA040538A patent/MA40538A/fr unknown
- 2015-08-26 US US15/504,223 patent/US10081616B2/en not_active Expired - Fee Related
- 2015-08-26 CA CA2958881A patent/CA2958881A1/en not_active Abandoned
- 2015-08-26 CN CN202010138750.0A patent/CN111454246A/zh active Pending
- 2015-08-26 WO PCT/US2015/046878 patent/WO2016033150A1/en not_active Ceased
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2018
- 2018-08-23 US US16/110,698 patent/US20180362499A1/en not_active Abandoned
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2020
- 2020-07-22 AU AU2020207828A patent/AU2020207828A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2015306643A1 (en) | 2017-03-16 |
| CN111454246A (zh) | 2020-07-28 |
| JP2017525777A (ja) | 2017-09-07 |
| EP3186228A1 (en) | 2017-07-05 |
| AU2020207828A1 (en) | 2020-08-13 |
| CN107074771A (zh) | 2017-08-18 |
| US20180362499A1 (en) | 2018-12-20 |
| US10081616B2 (en) | 2018-09-25 |
| EP3186228A4 (en) | 2018-04-18 |
| WO2016033150A1 (en) | 2016-03-03 |
| CN107074771B (zh) | 2020-03-20 |
| US20170240526A1 (en) | 2017-08-24 |
| MA40538A (fr) | 2021-04-07 |
| CA2958881A1 (en) | 2016-03-03 |
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