AU2014363904B2 - Trifluoromethyl pyrazolyl guanidine F1Fo-ATPase inhibitors and therapeutic uses thereof - Google Patents
Trifluoromethyl pyrazolyl guanidine F1Fo-ATPase inhibitors and therapeutic uses thereof Download PDFInfo
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- AU2014363904B2 AU2014363904B2 AU2014363904A AU2014363904A AU2014363904B2 AU 2014363904 B2 AU2014363904 B2 AU 2014363904B2 AU 2014363904 A AU2014363904 A AU 2014363904A AU 2014363904 A AU2014363904 A AU 2014363904A AU 2014363904 B2 AU2014363904 B2 AU 2014363904B2
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| PL2648511T3 (pl) | 2010-12-08 | 2017-12-29 | Lycera Corporation | Pirazoliloguanidynowe inhibitory F1F0-ATPaz i ich zastosowania terapeutyczne |
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| US9920012B2 (en) | 2012-06-08 | 2018-03-20 | Lycera Corporation | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
| WO2013185046A1 (en) | 2012-06-08 | 2013-12-12 | Lycera Corporation | Saturated acyl guanid1ne for inhibition of f1f0-atpase |
| JP6486364B2 (ja) | 2013-12-10 | 2019-03-20 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | トリフルオロメチルピラゾリルグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤及びその治療用途 |
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| CN116570589B (zh) * | 2023-05-30 | 2025-02-11 | 南阳理工学院 | 化合物Parimifasor在制备抗肿瘤药物中的应用 |
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| US4977189A (en) * | 1986-05-07 | 1990-12-11 | American Cyanamid Company | Substituted guanidinedicarbonyl derivatives |
| JPH07188197A (ja) | 1993-11-17 | 1995-07-25 | Fujisawa Pharmaceut Co Ltd | オキサゾール誘導体 |
| DE4344550A1 (de) | 1993-12-24 | 1995-06-29 | Hoechst Ag | Substituierte 1-Oxo-1,2-dihydro-isochinolinoyl- und 1,1-Dioxo-2H-1,2-benzothiazinoylguanidine, Verfahrenzu ihrer Herstellung, ihre Verwendung als Medikamentt oder Diagnostikum sowie sie enthaltendes Medikamen |
| US7041702B1 (en) | 1997-10-21 | 2006-05-09 | Scion Pharmaceuticals, Inc. | Pharmaceutically active compounds and methods of use |
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| US7276348B2 (en) | 1999-04-30 | 2007-10-02 | Regents Of The University Of Michigan | Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof |
| KR20020012310A (ko) | 1999-07-15 | 2002-02-15 | 다께우찌 마사야쓰 | 복소 방향환 화합물 |
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| WO2003050261A2 (en) | 2001-12-10 | 2003-06-19 | Bristol-Myers Squibb Company | (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial f1f0 atp hydrolase |
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| AU2003295402A1 (en) | 2002-11-06 | 2004-06-03 | Bristol-Myers Squibb Company | Acyl guanidine compounds and use thereof |
| EP1590338B1 (en) | 2002-12-04 | 2009-08-26 | Ore Pharmaceuticals Inc. | Modulators of melanocortin receptor |
| DE102004008141A1 (de) | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
| US20090275099A1 (en) | 2004-04-27 | 2009-11-05 | Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| US20050272723A1 (en) | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| JP4990766B2 (ja) | 2004-07-01 | 2012-08-01 | シンタ ファーマシューティカルズ コーポレーション | 二置換型ヘテロアリール化合物 |
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| WO2009036175A2 (en) | 2007-09-14 | 2009-03-19 | The Regents Of The University Of Michigan | F1f0-atpase inhibitors and related methods |
| AU2008345225A1 (en) | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| KR100982661B1 (ko) | 2008-04-22 | 2010-09-17 | 전남대학교산학협력단 | 플라스멥신 ⅱ 활성을 저해하는 화합물을 유효성분으로함유하는 말라리아 예방 및 치료를 위한 약학 조성물 및이를 이용한 말라리아 치료방법 |
| EP2352724B1 (en) | 2008-09-11 | 2015-04-22 | The Regents of the University of Michigan | Aryl guanidine f1f0-atpase inhibitors and their medical use |
| US9169199B2 (en) | 2010-12-08 | 2015-10-27 | Lycera Corporation | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
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- 2014-12-10 AU AU2014363904A patent/AU2014363904B2/en not_active Ceased
- 2014-12-10 EP EP14869792.3A patent/EP3080089B1/en not_active Not-in-force
- 2014-12-10 MX MX2016007445A patent/MX2016007445A/es unknown
- 2014-12-10 US US14/565,463 patent/US9266839B2/en not_active Expired - Fee Related
- 2014-12-10 CN CN201480072404.XA patent/CN105899489A/zh active Pending
- 2014-12-10 CA CA2931851A patent/CA2931851A1/en not_active Abandoned
- 2014-12-10 WO PCT/US2014/069487 patent/WO2015089149A1/en not_active Ceased
- 2014-12-10 BR BR112016013116A patent/BR112016013116A8/pt not_active Application Discontinuation
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2016
- 2016-02-04 US US15/015,403 patent/US9707211B2/en not_active Expired - Fee Related
- 2016-05-30 IL IL245930A patent/IL245930A0/en unknown
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2017
- 2017-06-23 US US15/631,380 patent/US10085972B2/en not_active Expired - Fee Related
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2018
- 2018-09-06 US US16/123,051 patent/US20190175556A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012078867A2 (en) * | 2010-12-08 | 2012-06-14 | Lycera Corporation | Cycloalkyl guanidine f1f0-atpase inhibitors and therapeutic uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016013116A2 (pt) | 2017-08-08 |
| US20170354643A1 (en) | 2017-12-14 |
| WO2015089149A1 (en) | 2015-06-18 |
| MX2016007445A (es) | 2016-09-09 |
| CN105899489A (zh) | 2016-08-24 |
| BR112016013116A8 (pt) | 2020-05-12 |
| IL245930A0 (en) | 2016-08-02 |
| US20150183745A1 (en) | 2015-07-02 |
| US10085972B2 (en) | 2018-10-02 |
| US9266839B2 (en) | 2016-02-23 |
| EP3080089A1 (en) | 2016-10-19 |
| JP2016539985A (ja) | 2016-12-22 |
| CA2931851A1 (en) | 2015-06-18 |
| EP3080089A4 (en) | 2017-08-23 |
| US20160287559A1 (en) | 2016-10-06 |
| JP6486364B2 (ja) | 2019-03-20 |
| AU2014363904A1 (en) | 2016-06-30 |
| US20190175556A1 (en) | 2019-06-13 |
| US9707211B2 (en) | 2017-07-18 |
| EP3080089B1 (en) | 2019-05-08 |
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