AU2014340006B2 - Chitosan stenting paste - Google Patents
Chitosan stenting paste Download PDFInfo
- Publication number
- AU2014340006B2 AU2014340006B2 AU2014340006A AU2014340006A AU2014340006B2 AU 2014340006 B2 AU2014340006 B2 AU 2014340006B2 AU 2014340006 A AU2014340006 A AU 2014340006A AU 2014340006 A AU2014340006 A AU 2014340006A AU 2014340006 B2 AU2014340006 B2 AU 2014340006B2
- Authority
- AU
- Australia
- Prior art keywords
- paste
- water
- osmolality
- soluble chitosan
- reducing agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0031—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0071—Plasticisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers & Plastics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/061,993 | 2013-10-24 | ||
| US14/061,993 US9192692B2 (en) | 2013-10-24 | 2013-10-24 | Chitosan stenting paste |
| US14/319,901 US9192574B2 (en) | 2013-10-24 | 2014-06-30 | Chitosan paste wound dressing |
| US14/319,901 | 2014-06-30 | ||
| PCT/US2014/062029 WO2015061606A1 (en) | 2013-10-24 | 2014-10-23 | Chitosan stenting paste |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2014340006A1 AU2014340006A1 (en) | 2016-05-12 |
| AU2014340006B2 true AU2014340006B2 (en) | 2018-06-28 |
Family
ID=51862592
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014340006A Active AU2014340006B2 (en) | 2013-10-24 | 2014-10-23 | Chitosan stenting paste |
| AU2014340012A Active AU2014340012B2 (en) | 2013-10-24 | 2014-10-23 | Chitosan paste wound dressing |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014340012A Active AU2014340012B2 (en) | 2013-10-24 | 2014-10-23 | Chitosan paste wound dressing |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9192574B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3060266B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6491647B2 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2014340006B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2926401C (cg-RX-API-DMAC7.html) |
| ES (2) | ES2765348T3 (cg-RX-API-DMAC7.html) |
| WO (2) | WO2015061606A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8932560B2 (en) | 2007-09-04 | 2015-01-13 | University of Maryland, College Parke | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells |
| US8668899B2 (en) | 2009-11-13 | 2014-03-11 | University Of Maryland, College Park | Advanced functional biocompatible foam used as a hemostatic agent for compressible and non-compressible acute wounds |
| CA2914610C (en) | 2013-03-13 | 2022-08-02 | University Of Maryland | Advanced functional biocompatible polymer putty used as a hemostatic agent for treating damaged tissue and cells |
| CN108610437A (zh) | 2013-03-14 | 2018-10-02 | 金珂生物医疗公司 | 生物相容的和生物可吸收的衍生的壳聚糖组合物 |
| EP3341081B1 (en) | 2015-08-27 | 2020-11-11 | PrecisionBiotics Group Limited | Use of bifidobacterium longum and an exopolysaccharide produced thereby |
| US10576099B2 (en) | 2016-10-21 | 2020-03-03 | Covidien Lp | Injectable scaffold for treatment of intracranial aneurysms and related technology |
| ES2867230T3 (es) * | 2016-10-26 | 2021-10-20 | Biointelligence Systems S L | Composición bioactiva ósea y usos de la misma |
| WO2020162764A1 (en) * | 2019-02-08 | 2020-08-13 | Chitogel Limited | Surgical hydrogel |
| US11826863B2 (en) | 2019-11-04 | 2023-11-28 | Covidien Lp | Systems and methods for treating aneurysms |
| EP4308013A1 (en) | 2021-03-16 | 2024-01-24 | Covidien LP | Injectable biopolymer compositions and associated systems and methods |
| EP4084580A1 (en) * | 2021-04-30 | 2022-11-02 | Koninklijke Philips N.V. | A light output system and design method |
| KR102852787B1 (ko) * | 2021-12-28 | 2025-08-28 | 단국대학교 천안캠퍼스 산학협력단 | 신규한 화합물을 포함하는 생리 식염수 |
| WO2024102389A1 (en) * | 2022-11-10 | 2024-05-16 | Hemostasis, Llc | Dressing formulations |
| CN116059430B (zh) * | 2022-12-16 | 2025-09-23 | 无锡学院 | 一种可降解伤口敷料及其制备方法 |
Citations (6)
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|---|---|---|---|---|
| WO1996013284A1 (en) * | 1994-10-28 | 1996-05-09 | Innovative Technologies Limited | Wound treatment composition |
| WO1999007416A1 (en) * | 1997-08-04 | 1999-02-18 | Bio-Syntech Ltd. | TEMPERATURE-CONTROLLED pH-DEPENDANT FORMATION OF IONIC POLYSACCHARIDE GELS |
| WO2002040072A2 (en) * | 2000-11-15 | 2002-05-23 | Bio Syntech Canada Inc. | Filler composition for soft tissue augmentation and reconstructive surgery |
| US20030143274A1 (en) * | 1991-10-30 | 2003-07-31 | Viegas Tacey X. | Medical uses of in situ formed gels |
| WO2010033943A1 (en) * | 2008-09-19 | 2010-03-25 | The Trustees Of The University Of Pennsylvania | Biodegradable stent |
| WO2011060545A1 (en) * | 2009-11-19 | 2011-05-26 | Corporation De L'ecole Polytechnique De Montreal | Specific blood:chitosan mixing ratios producing a viscous paste-like implant with good handling properties for tissue repair |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4394373A (en) | 1981-04-06 | 1983-07-19 | Malette William Graham | Method of achieving hemostasis |
| US4532134A (en) | 1981-04-06 | 1985-07-30 | Malette William Graham | Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound |
| US4452785A (en) | 1982-11-08 | 1984-06-05 | Malette William Graham | Method for the therapeutic occlusion |
| CA1202904A (en) | 1983-11-21 | 1986-04-08 | Brian G. Sparkes | Chitosan based wound dressing materials |
| US4659700A (en) | 1984-03-02 | 1987-04-21 | Johnson & Johnson Products, Inc. | Chitosan-glycerol-water gel |
| JPH0735281B2 (ja) | 1988-02-16 | 1995-04-19 | 学校法人松本歯科大学 | 硬化性組成物 |
| US4956350A (en) | 1988-08-18 | 1990-09-11 | Minnesota Mining And Manufacturing Company | Wound filling compositions |
| US5124151A (en) | 1990-08-07 | 1992-06-23 | Mediventures Inc. | Drug delivery by injection with thermo-irreversible gels |
| US5871985A (en) | 1992-09-28 | 1999-02-16 | Brown University Research Foundation | Particulate non cross-linked chitosan core matrices for encapsulated cells |
| GB2276819B (en) | 1993-03-23 | 1996-12-11 | Johnson & Johnson Medical | Aqueous wound treatment composition comprising a polysaccharide and hexylene glycol |
| US5531716A (en) | 1993-09-29 | 1996-07-02 | Hercules Incorporated | Medical devices subject to triggered disintegration |
| US5622834A (en) | 1993-12-01 | 1997-04-22 | Marine Polymer Technologies, Inc. | Method of isolating poly-β-1-4-N-acetylglucosamine from microalgal culture |
| SE9402531L (sv) | 1994-07-19 | 1996-01-20 | Medicarb Ab | Sårläkningsmedel |
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| US6458375B1 (en) | 1998-02-27 | 2002-10-01 | Musculoskeletal Transplant Foundation | Malleable paste with allograft bone reinforcement for filling bone defects |
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| EP1190702A1 (en) | 2000-09-22 | 2002-03-27 | Ciba SC Holding AG | Chitosan emulsion formulation |
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| ATA13842001A (de) | 2001-08-31 | 2002-10-15 | Mucobiomer Biotechnologische F | Chitosan-thio-alkyl-amidin konjugate und deren kosmetische sowie pharmazeutische verwendung |
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| JP3947391B2 (ja) | 2001-11-28 | 2007-07-18 | 独立行政法人 日本原子力研究開発機構 | 橋かけ構造を有するキチン誘導体及び/又はキトサン誘導体の製造方法 |
| FR2836044A1 (fr) | 2002-02-15 | 2003-08-22 | Octaris | Composition pour la reparation et la cicatrisation cutanee comprenant exclusivement un vrai hydrogel physique de chitosane |
| US20060127873A1 (en) | 2002-07-16 | 2006-06-15 | Caroline Hoemann | Composition for cytocompatible, injectable, self-gelling chitosan solutions for encapsulating and delivering live cells or biologically active factors |
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| JP2006347883A (ja) * | 2003-09-08 | 2006-12-28 | Neetec:Kk | 糖鎖含有キトサン誘導体及びグリコサミノグリカンを含有する医療用組成物 |
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| RU2007122799A (ru) | 2004-12-20 | 2009-01-27 | КарбГрафт АБ (SE) | Хитозановые композиции |
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| EP1986692B1 (en) | 2006-01-25 | 2018-03-07 | University Of Virginia Patent Foundation | Methods for regulating gelation of chitosan solutions and uses thereof |
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| US20100178313A1 (en) | 2007-06-13 | 2010-07-15 | Fmc Corporation | Implantable Degradable Biopolymer Fiber Devices |
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| JP2011513034A (ja) | 2008-03-10 | 2011-04-28 | マーフライ・2・リミテッド・パートナーシップ | 骨セメント組成物 |
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| CN102216381B (zh) | 2008-04-24 | 2016-06-15 | 麦德托尼克公司 | 可再水化的多糖颗粒和海绵体 |
| AU2009240511B2 (en) | 2008-04-24 | 2015-01-22 | Medtronic, Inc. | Thiolated chitosan gel |
| EP2303254B1 (en) | 2008-06-12 | 2019-10-30 | Medtronic Xomed, Inc. | Product for treating chronic wounds with an extracellular polymeric substance solvating system |
| CA2806559C (en) | 2009-09-02 | 2018-06-26 | Synedgen Inc. | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds |
| US9427469B2 (en) | 2009-11-19 | 2016-08-30 | Ortho Regenerative Technologies Inc. | Soluble physiological chitosan formulations combined with platelet-rich plasma (PRP) for tissue repair |
| CN102469782A (zh) | 2010-06-18 | 2012-05-23 | 哈洛资源公司 | 包含壳聚糖的固态共混物的制剂及方法 |
| US8506972B2 (en) | 2010-08-27 | 2013-08-13 | Oligo Medic Inc | Highly biocompatible dual thermogelling chitosan/glucosamine salt compositions |
-
2014
- 2014-06-30 US US14/319,901 patent/US9192574B2/en active Active
- 2014-10-23 ES ES14793730T patent/ES2765348T3/es active Active
- 2014-10-23 CA CA2926401A patent/CA2926401C/en not_active Expired - Fee Related
- 2014-10-23 EP EP14793731.2A patent/EP3060266B1/en active Active
- 2014-10-23 EP EP14793730.4A patent/EP3060265B1/en active Active
- 2014-10-23 ES ES14793731T patent/ES2755137T3/es active Active
- 2014-10-23 JP JP2016518431A patent/JP6491647B2/ja active Active
- 2014-10-23 AU AU2014340006A patent/AU2014340006B2/en active Active
- 2014-10-23 WO PCT/US2014/062029 patent/WO2015061606A1/en not_active Ceased
- 2014-10-23 AU AU2014340012A patent/AU2014340012B2/en active Active
- 2014-10-23 WO PCT/US2014/062041 patent/WO2015061612A1/en not_active Ceased
- 2014-10-23 CA CA2927357A patent/CA2927357A1/en not_active Abandoned
- 2014-10-23 JP JP2016522114A patent/JP6397491B2/ja active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20030143274A1 (en) * | 1991-10-30 | 2003-07-31 | Viegas Tacey X. | Medical uses of in situ formed gels |
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Also Published As
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|---|---|
| WO2015061612A1 (en) | 2015-04-30 |
| JP6397491B2 (ja) | 2018-09-26 |
| US20150119358A1 (en) | 2015-04-30 |
| JP6491647B2 (ja) | 2019-03-27 |
| JP2016534050A (ja) | 2016-11-04 |
| CA2926401C (en) | 2019-08-20 |
| CA2926401A1 (en) | 2015-04-30 |
| ES2765348T3 (es) | 2020-06-08 |
| US9192574B2 (en) | 2015-11-24 |
| CA2927357A1 (en) | 2015-04-30 |
| JP2016533775A (ja) | 2016-11-04 |
| ES2755137T3 (es) | 2020-04-21 |
| EP3060266B1 (en) | 2019-09-04 |
| AU2014340012B2 (en) | 2018-06-28 |
| EP3060265A1 (en) | 2016-08-31 |
| EP3060266A1 (en) | 2016-08-31 |
| WO2015061606A1 (en) | 2015-04-30 |
| EP3060265B1 (en) | 2019-11-27 |
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