AU2014339035A1 - Sirna and their use in methods and compositions for inhibiting the expression of the ORAI1 gene - Google Patents
Sirna and their use in methods and compositions for inhibiting the expression of the ORAI1 gene Download PDFInfo
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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EP20130382415 EP2865758A1 (fr) | 2013-10-22 | 2013-10-22 | ARNsi et leur utilisation dans des procédés et des compositions pour inhiber l'expression du gène ORAI1 |
EP13382415.1 | 2013-10-22 | ||
PCT/EP2014/072514 WO2015059122A2 (fr) | 2013-10-22 | 2014-10-21 | Arnsi et leur utilisation dans des procédés et des compositions pour inhiber l'expression du gène orai1 |
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AU2014339035A1 true AU2014339035A1 (en) | 2016-05-12 |
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Family Applications (1)
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AU2014339035A Abandoned AU2014339035A1 (en) | 2013-10-22 | 2014-10-21 | Sirna and their use in methods and compositions for inhibiting the expression of the ORAI1 gene |
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Country | Link |
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US (2) | US10167473B2 (fr) |
EP (2) | EP2865758A1 (fr) |
JP (1) | JP2016535592A (fr) |
KR (1) | KR20160078384A (fr) |
CN (1) | CN107223154A (fr) |
AU (1) | AU2014339035A1 (fr) |
BR (1) | BR112016008786A2 (fr) |
CA (1) | CA2928515A1 (fr) |
IL (1) | IL245123A0 (fr) |
MX (1) | MX2016005042A (fr) |
RU (1) | RU2689607C2 (fr) |
SG (2) | SG11201603113WA (fr) |
WO (1) | WO2015059122A2 (fr) |
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BR112017018029B1 (pt) * | 2015-03-20 | 2021-06-15 | Unilever Ip Holdings B.V. | Molécula de sirna, método para a redução da perspiração, composição antiperspirante e uso de uma composição antiperspirante |
MA44908A (fr) * | 2015-09-08 | 2018-07-18 | Sylentis Sau | Molécules d'arnsi et leur utilisation dans des procédés et des compositions pour inhiber l'expression du gène nrarp |
WO2017042239A1 (fr) * | 2015-09-08 | 2017-03-16 | Sylentis Sau | Molécules d'arnsi et leur utilisation dans des procédés et des compositions pour l'inhibition de l'expression du gène chi3l1 |
WO2017096326A1 (fr) | 2015-12-02 | 2017-06-08 | Massachusetts Institute Of Technology | Méthode de production efficace de neurones à partir de cellules non neuronales |
CN105477637A (zh) * | 2015-12-16 | 2016-04-13 | 孙荣距 | Orai1基因沉默在血管内皮细胞钙超载损伤中的应用 |
EP4419681A1 (fr) * | 2021-10-22 | 2024-08-28 | Association Française contre les Myopathies (AFM) | Méthode de traitement de myopathie à agrégats tubulaires et de syndrome de stormorken |
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CZ308053B6 (cs) | 2000-12-01 | 2019-11-27 | Max Planck Gesellschaft | Izolovaná molekula dvouřetězcové RNA, způsob její výroby a její použití |
SI3222724T1 (sl) * | 2002-08-05 | 2019-03-29 | Silence Therapeutics Gmbh | Nadaljnje nove oblike molekul interferenčne RNA |
US7250496B2 (en) * | 2002-11-14 | 2007-07-31 | Rosetta Genomics Ltd. | Bioinformatically detectable group of novel regulatory genes and uses thereof |
DK2284266T3 (da) * | 2002-11-14 | 2014-01-13 | Thermo Fisher Scient Biosciences Inc | sIRNA-MOLEKYLE MOD TP53 |
WO2005062937A2 (fr) | 2003-12-22 | 2005-07-14 | University Of Massachusetts | Procedes et compositions d'amelioration de l'efficacite de la specificite d'un siarn a extremite emoussee simple et double |
AU2005276245C1 (en) * | 2004-08-23 | 2015-02-26 | Sylentis S.A.U. | Treatment of eye disorders characterized by an elevated introacular pressure by siRNAs |
CN101467046A (zh) | 2006-04-10 | 2009-06-24 | 皇后医学中心 | Crac调节剂及其在药物发现中的用途 |
TW201336514A (zh) * | 2006-04-13 | 2013-09-16 | Alcon Res Ltd | RNA干擾(RNAi)所媒介之與脾酪胺酸激酶相關之發炎症狀的抑制作用(二) |
GB0608838D0 (en) | 2006-05-04 | 2006-06-14 | Novartis Ag | Organic compounds |
JP2010507387A (ja) | 2006-10-25 | 2010-03-11 | クアーク・ファーマスーティカルス、インコーポレイテッド | 新規のsiRNAおよびその使用方法 |
WO2008104978A2 (fr) | 2007-02-28 | 2008-09-04 | Quark Pharmaceuticals, Inc. | Nouvelles structures d'arnsi |
US8431536B2 (en) * | 2007-03-05 | 2013-04-30 | The University Of Queensland | Target for breast cancer therapy and/or diagnosis |
JP5646997B2 (ja) | 2007-10-03 | 2014-12-24 | クォーク ファーマシューティカルズ インコーポレーティッドQuark Pharmaceuticals,Inc. | 新規siRNA構造 |
GB0801888D0 (en) | 2008-02-01 | 2008-03-12 | Isis Innovation | Treatment of mast cell related disorders |
US20120165265A1 (en) | 2009-02-26 | 2012-06-28 | Dolmetsch Ricardo E | Calcium Signaling Modulators Involving STIM and ORAI Proteins |
US20120264231A1 (en) | 2009-06-19 | 2012-10-18 | Immune Disease Institute, Inc. | Assay for orai calcium channel regulators |
CA2767225A1 (fr) * | 2009-07-06 | 2011-01-13 | Alnylam Pharmaceuticals, Inc. | Compositions et procedes pour ameliorer la production d'un produit biologique |
US8993612B2 (en) | 2009-10-08 | 2015-03-31 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer |
US8377970B2 (en) * | 2009-10-08 | 2013-02-19 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel |
KR101237036B1 (ko) | 2009-11-04 | 2013-02-25 | 성균관대학교산학협력단 | 안티센스 가닥에 의한 오프-타겟 효과를 최소화한 신규한 siRNA 구조 및 그 용도 |
CN102827843A (zh) * | 2012-09-25 | 2012-12-19 | 陈志南 | 一种针对Orai1基因、抑制肿瘤增殖和转移的shRNA及其应用 |
-
2013
- 2013-10-22 EP EP20130382415 patent/EP2865758A1/fr not_active Withdrawn
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2014
- 2014-10-21 MX MX2016005042A patent/MX2016005042A/es unknown
- 2014-10-21 WO PCT/EP2014/072514 patent/WO2015059122A2/fr active Application Filing
- 2014-10-21 CA CA2928515A patent/CA2928515A1/fr not_active Abandoned
- 2014-10-21 SG SG11201603113WA patent/SG11201603113WA/en unknown
- 2014-10-21 CN CN201480058269.3A patent/CN107223154A/zh active Pending
- 2014-10-21 RU RU2016119354A patent/RU2689607C2/ru active
- 2014-10-21 KR KR1020167013215A patent/KR20160078384A/ko not_active Application Discontinuation
- 2014-10-21 SG SG10201802865PA patent/SG10201802865PA/en unknown
- 2014-10-21 JP JP2016525603A patent/JP2016535592A/ja active Pending
- 2014-10-21 AU AU2014339035A patent/AU2014339035A1/en not_active Abandoned
- 2014-10-21 EP EP14802816.0A patent/EP3060663A2/fr not_active Withdrawn
- 2014-10-21 US US15/030,176 patent/US10167473B2/en active Active
- 2014-10-21 BR BR112016008786A patent/BR112016008786A2/pt not_active Application Discontinuation
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2016
- 2016-04-14 IL IL245123A patent/IL245123A0/en unknown
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2018
- 2018-12-14 US US16/220,865 patent/US20190106700A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
RU2016119354A (ru) | 2017-12-01 |
WO2015059122A3 (fr) | 2015-08-20 |
SG11201603113WA (en) | 2016-05-30 |
WO2015059122A2 (fr) | 2015-04-30 |
JP2016535592A (ja) | 2016-11-17 |
US20190106700A1 (en) | 2019-04-11 |
IL245123A0 (en) | 2016-06-30 |
BR112016008786A2 (pt) | 2017-10-03 |
MX2016005042A (es) | 2016-08-17 |
KR20160078384A (ko) | 2016-07-04 |
US20160304880A1 (en) | 2016-10-20 |
SG10201802865PA (en) | 2018-05-30 |
RU2689607C2 (ru) | 2019-05-28 |
EP3060663A2 (fr) | 2016-08-31 |
CN107223154A (zh) | 2017-09-29 |
EP2865758A1 (fr) | 2015-04-29 |
CA2928515A1 (fr) | 2015-04-30 |
RU2016119354A3 (fr) | 2018-04-28 |
US10167473B2 (en) | 2019-01-01 |
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