AU2013366450A1 - Immunogenic composition comprising elements of C. difficile CDTb and/or CDTa proteins - Google Patents

Immunogenic composition comprising elements of C. difficile CDTb and/or CDTa proteins Download PDF

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Publication number
AU2013366450A1
AU2013366450A1 AU2013366450A AU2013366450A AU2013366450A1 AU 2013366450 A1 AU2013366450 A1 AU 2013366450A1 AU 2013366450 A AU2013366450 A AU 2013366450A AU 2013366450 A AU2013366450 A AU 2013366450A AU 2013366450 A1 AU2013366450 A1 AU 2013366450A1
Authority
AU
Australia
Prior art keywords
seq
protein
cdtb
cdta
immunogenic composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2013366450A
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English (en)
Inventor
Cindy Castado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
GlaxoSmithKline Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Biologicals SA filed Critical GlaxoSmithKline Biologicals SA
Publication of AU2013366450A1 publication Critical patent/AU2013366450A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2013366450A 2012-12-23 2013-12-20 Immunogenic composition comprising elements of C. difficile CDTb and/or CDTa proteins Abandoned AU2013366450A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1223342.5A GB201223342D0 (en) 2012-12-23 2012-12-23 Immunogenic composition
GB1223342.5 2012-12-23
PCT/EP2013/077762 WO2014096393A1 (en) 2012-12-23 2013-12-20 Immunogenic composition comprising elements of c. difficile cdtb and/or cdta proteins

Publications (1)

Publication Number Publication Date
AU2013366450A1 true AU2013366450A1 (en) 2015-07-23

Family

ID=47682553

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013366450A Abandoned AU2013366450A1 (en) 2012-12-23 2013-12-20 Immunogenic composition comprising elements of C. difficile CDTb and/or CDTa proteins

Country Status (12)

Country Link
US (2) US9669083B2 (https=)
EP (1) EP2934579B1 (https=)
JP (1) JP6515036B2 (https=)
CN (1) CN105120892B (https=)
AR (1) AR094275A1 (https=)
AU (1) AU2013366450A1 (https=)
BR (1) BR112015014727B8 (https=)
CA (1) CA2894951C (https=)
ES (1) ES2748054T3 (https=)
GB (1) GB201223342D0 (https=)
SG (1) SG11201504701UA (https=)
WO (1) WO2014096393A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2753352T5 (pl) 2010-09-03 2022-10-17 Valneva Austria Gmbh Izolowany polipeptyd białek toksyny a i toksyny b z c. difficile i jego zastosowania
TWI815599B (zh) 2011-04-22 2023-09-11 美商惠氏有限責任公司 與難養芽胞梭菌(Clostridium difficile)之突變毒素有關之組成物及彼之方法
WO2013084071A2 (en) * 2011-12-08 2013-06-13 Novartis Ag Clostridium difficile toxin-based vaccine
BR122016023101B1 (pt) * 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
BE1022949B1 (fr) * 2014-06-25 2016-10-21 Glaxosmithkline Biologicals S.A. Composition immunogene
MX2019010948A (es) * 2017-03-15 2020-01-09 Novavax Inc Métodos y composiciones para inducir respuestas inmunitarias contra clostridium difficile.
US10933126B2 (en) 2018-05-03 2021-03-02 The Board Of Regents Of The University Of Oklahoma Clostridium difficile immunogenic compositions and methods of use
US12076352B2 (en) 2018-06-19 2024-09-03 Glaxosmithkline Biologicals Sa Immunogenic composition
CN111793130B (zh) * 2019-03-20 2021-09-14 华中农业大学 一株副猪嗜血杆菌CdtB杂交瘤细胞及单克隆抗体应用
WO2021022033A1 (en) 2019-07-30 2021-02-04 Leung Kai P Layered composite for scar treatment and prevention
WO2021255690A2 (en) 2020-06-19 2021-12-23 Pfizer Inc. Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof
GB202205833D0 (en) 2022-04-21 2022-06-08 Glaxosmithkline Biologicals Sa Bacteriophage
WO2025029561A2 (en) * 2023-07-28 2025-02-06 University Of South Florida Vaccine containing rbd2 of cdtb component from binary toxin cdt of clostridioides difficile

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2656850T3 (es) * 2009-02-11 2018-02-28 Cedars-Sinai Medical Center Diagnóstico del síndrome intestinal inflamatorio con base en la toxina de distensión citoletal
US10046040B2 (en) * 2009-11-16 2018-08-14 University Of Maryland, Baltimore Multivalent live vector vaccine against Clostridium difficile-associated disease
PL2753352T5 (pl) * 2010-09-03 2022-10-17 Valneva Austria Gmbh Izolowany polipeptyd białek toksyny a i toksyny b z c. difficile i jego zastosowania
AR089797A1 (es) 2012-01-27 2014-09-17 Merck Sharp & Dohme Vacunas contra clostridum difficile que comprenden toxinas recombinantes

Also Published As

Publication number Publication date
US9669083B2 (en) 2017-06-06
JP6515036B2 (ja) 2019-05-15
GB201223342D0 (en) 2013-02-06
US20180043005A1 (en) 2018-02-15
BR112015014727B1 (pt) 2022-08-02
BR112015014727B8 (pt) 2022-09-20
CN105120892A (zh) 2015-12-02
CA2894951C (en) 2023-05-09
CN105120892B (zh) 2020-07-31
AR094275A1 (es) 2015-07-22
SG11201504701UA (en) 2015-07-30
BR112015014727A2 (pt) 2017-10-10
JP2016504993A (ja) 2016-02-18
EP2934579A1 (en) 2015-10-28
EP2934579B1 (en) 2019-08-07
US20150313985A1 (en) 2015-11-05
CA2894951A1 (en) 2014-06-26
ES2748054T3 (es) 2020-03-12
WO2014096393A1 (en) 2014-06-26

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted