AU2013323775B2 - Desmoglein 2 (DSG2) binding proteins and uses therefor - Google Patents

Desmoglein 2 (DSG2) binding proteins and uses therefor Download PDF

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AU2013323775B2
AU2013323775B2 AU2013323775A AU2013323775A AU2013323775B2 AU 2013323775 B2 AU2013323775 B2 AU 2013323775B2 AU 2013323775 A AU2013323775 A AU 2013323775A AU 2013323775 A AU2013323775 A AU 2013323775A AU 2013323775 B2 AU2013323775 B2 AU 2013323775B2
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AU2013323775A1 (en
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Andre Lieber
Hongjie Wang
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University of Washington Center for Commercialization
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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AU2013323775A 2012-09-25 2013-09-24 Desmoglein 2 (DSG2) binding proteins and uses therefor Active AU2013323775B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261705523P 2012-09-25 2012-09-25
US61/705,523 2012-09-25
PCT/US2013/061431 WO2014052322A1 (en) 2012-09-25 2013-09-24 Desmoglein 2 (dsg2) binding proteins and uses therefor

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AU2013323775A1 AU2013323775A1 (en) 2015-04-09
AU2013323775B2 true AU2013323775B2 (en) 2018-10-18

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US (1) US20150246949A1 (enExample)
EP (1) EP2900818B1 (enExample)
JP (1) JP6290221B2 (enExample)
KR (1) KR102175034B1 (enExample)
CN (2) CN109796524A (enExample)
AU (1) AU2013323775B2 (enExample)
WO (1) WO2014052322A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (en) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
TWI791440B (zh) * 2016-06-06 2023-02-11 艾斯克立必恩股份有限公司 Dsg2-衍生肽
JP6923957B2 (ja) 2016-06-06 2021-08-25 アスクリピウム タイワン シーオー．， エルティーディー．Ａｓｃｌｅｐｉｕｍｍ Ｔａｉｗａｎ Ｃｏ．， Ｌｔｄ． Ｄｓｇ２モノクローナル抗体およびその応用
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
US20200347101A1 (en) * 2018-01-25 2020-11-05 Pai Life Sciences, Inc. Conjugatable desmoglein 2 (dsg2) binding proteins and uses therefor
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
WO2021072112A1 (en) 2019-10-09 2021-04-15 Hdt Bio Corp. Detection of desmoglein-2 in cancers of epithelial origin
CN111879940B (zh) * 2020-04-28 2022-02-01 中国科学院微生物研究所 肺结核标志物及应用

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
US5211657A (en) 1988-11-07 1993-05-18 The United States Government As Represented By The Secretary Of The Department Of Health And Human Services Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides
AU767975B2 (en) 1998-09-11 2003-11-27 Genvec, Inc. Alternatively targeted adenovirus
CA2392272A1 (fr) 1999-11-25 2001-05-31 Transgene S.A. Fibre adenovirable modifiee et utilisations
SG98393A1 (en) 2000-05-19 2003-09-19 Inst Materials Research & Eng Injectable drug delivery systems with cyclodextrin-polymer based hydrogels
US6635466B2 (en) * 2001-01-09 2003-10-21 University Of Iowa Research Foundation Adenovirus serotype 30 (Ad30)
EP1531757B1 (en) 2002-07-19 2016-09-07 Omeros Corporation Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from
US20050181375A1 (en) * 2003-01-10 2005-08-18 Natasha Aziz Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer
CN101068933A (zh) * 2004-08-25 2007-11-07 细胞基因系统有限公司 用于肿瘤细胞增强转导的纤维修饰的腺病毒载体
US8722853B2 (en) * 2010-06-10 2014-05-13 University Of Washington Through Its Center For Commercialization Methods and systems for adenovirus interaction with desmoglein 2 (DSG2)

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US20150246949A1 (en) 2015-09-03
CN105008535A (zh) 2015-10-28
JP2015532265A (ja) 2015-11-09
AU2013323775A1 (en) 2015-04-09
KR102175034B1 (ko) 2020-11-06
CN105008535B (zh) 2018-10-16
CN109796524A (zh) 2019-05-24
WO2014052322A1 (en) 2014-04-03
EP2900818B1 (en) 2017-06-07
JP6290221B2 (ja) 2018-03-07
EP2900818A1 (en) 2015-08-05
KR20150058463A (ko) 2015-05-28

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