AU2013308045B2 - Methods for the treatment of hepatitis B and hepatitis D infections - Google Patents
Methods for the treatment of hepatitis B and hepatitis D infections Download PDFInfo
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- AU2013308045B2 AU2013308045B2 AU2013308045A AU2013308045A AU2013308045B2 AU 2013308045 B2 AU2013308045 B2 AU 2013308045B2 AU 2013308045 A AU2013308045 A AU 2013308045A AU 2013308045 A AU2013308045 A AU 2013308045A AU 2013308045 B2 AU2013308045 B2 AU 2013308045B2
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| AU2013262416B2 (en) | 2012-05-18 | 2017-05-11 | Replicor Inc. | Oligonucleotide chelate complex-polypeptide compositions and methods |
| KR102025679B1 (ko) | 2012-08-30 | 2019-09-26 | 레플리코르 인코포레이티드 | Ｂ형 간염 및 ｄ형 간염 감염증의 치료 방법 |
| HK1231402A1 (zh) * | 2014-07-10 | 2017-12-22 | Replicor Inc. | 治疗b型肝炎和d型肝炎病毒感染的方法 |
| WO2016030863A1 (en) | 2014-08-29 | 2016-03-03 | Glaxosmithkline Intellectual Property Development Limited | Compounds and methods for treating viral infections |
| US20160175245A1 (en) * | 2014-12-19 | 2016-06-23 | Mycotoxins Therapy, Llc | Treatment of diseases associated with mold and mycotoxin exposure |
| US20170016000A1 (en) | 2015-07-17 | 2017-01-19 | Arcturus Therapeutics, Inc. | Compositions and agents against hepatitis b virus and uses thereof |
| US20170137821A1 (en) | 2015-07-17 | 2017-05-18 | Arcturus Therapeutics, Inc. | Molecules and agents for treating hepatitis b virus |
| HK1248278A1 (zh) * | 2015-07-29 | 2018-10-12 | Arbutus Biopharma Corporation | 用於使乙型肝炎病毒基因表达沉默的组合物及方法 |
| WO2017059878A1 (en) * | 2015-10-07 | 2017-04-13 | Humabs Biomed Sa | Antibodies that potently neutralize hepatitis b virus and uses thereof |
| ES3008560T3 (en) | 2016-02-19 | 2025-03-24 | Eit Pharma Inc | Treatment of hepatitis delta virus infection with interferon lambda |
| CA3065518A1 (en) * | 2017-05-31 | 2018-12-06 | Arbutus Biopharma Corporation | Therapeutic compositions and methods for treating hepatitis b |
| TWI815887B (zh) * | 2018-05-15 | 2023-09-21 | 美商愛彼特生物製藥股份有限公司 | 經取代的2,2'-雙嘧啶基化合物、其類似物及其使用方法 |
| US11166976B2 (en) | 2018-11-08 | 2021-11-09 | Aligos Therapeutics, Inc. | S-antigen transport inhibiting oligonucleotide polymers and methods |
| US12304946B2 (en) | 2018-12-19 | 2025-05-20 | Humabs Biomed Sa | Antibodies that neutralize hepatitis B virus and uses thereof |
| KR20210126559A (ko) | 2018-12-20 | 2021-10-20 | 비르 바이오테크놀로지, 인코포레이티드 | 병용 hbv 요법 |
| WO2021130266A1 (en) * | 2019-12-24 | 2021-07-01 | F. Hoffmann-La Roche Ag | Pharmaceutical combination of a therapeutic oligonucleotide targeting hbv and a tlr7 agonist for treatment of hbv |
| CN114507663A (zh) * | 2020-11-16 | 2022-05-17 | 浙江柏拉阿图医药科技有限公司 | 寡核苷酸及其在抗乙型肝炎和丁型肝炎病毒中的应用 |
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| WO2011047312A1 (en) * | 2009-10-16 | 2011-04-21 | Glaxo Group Limited | Hbv antisense inhibitors |
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| US20030206887A1 (en) | 1992-05-14 | 2003-11-06 | David Morrissey | RNA interference mediated inhibition of hepatitis B virus (HBV) using short interfering nucleic acid (siNA) |
| US20040127446A1 (en) * | 1992-05-14 | 2004-07-01 | Lawrence Blatt | Oligonucleotide mediated inhibition of hepatitis B virus and hepatitis C virus replication |
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| IL118625A0 (en) * | 1996-06-11 | 1996-10-16 | Xtl Biopharmaceuticals Limited | Anti HBV antibodies |
| DE19725803C1 (de) | 1997-06-18 | 1999-02-11 | Deutsches Krebsforsch | HBV-gerichtete Antisense-Nukleinsäuren |
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| WO2011047316A1 (en) | 2009-10-16 | 2011-04-21 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Nucleic acid sequences encoding expandable hiv mosaic proteins |
| CA2746981A1 (en) * | 2010-08-05 | 2012-02-05 | Replicor Inc. | Methods for inhibition of apolipoprotein h |
| WO2012021985A1 (en) | 2010-08-20 | 2012-02-23 | Replicor Inc. | Oligonucleotide chelate complexes |
| US8921381B2 (en) * | 2010-10-04 | 2014-12-30 | Baruch S. Blumberg Institute | Inhibitors of secretion of hepatitis B virus antigens |
| CN103582648B (zh) | 2011-04-21 | 2016-08-31 | Isis制药公司 | 乙型肝炎病毒(hbv)表达的调节 |
| HRP20181564T1 (hr) | 2011-06-30 | 2018-11-30 | Arrowhead Pharmaceuticals, Inc. | Pripravci i postupci za inhibiciju ekspresije gena virusa hepatitisa b |
| AU2013262416B2 (en) * | 2012-05-18 | 2017-05-11 | Replicor Inc. | Oligonucleotide chelate complex-polypeptide compositions and methods |
| AR091065A1 (es) | 2012-05-18 | 2014-12-30 | Replicor Inc | Una formulacion farmaceutica que comprende un quelato de oligonucleotidos antiviral para el tratamiento de una infeccion antiviral |
| KR102025679B1 (ko) | 2012-08-30 | 2019-09-26 | 레플리코르 인코포레이티드 | Ｂ형 간염 및 ｄ형 간염 감염증의 치료 방법 |
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Patent Citations (3)
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| CA2254931A1 (en) * | 1996-06-11 | 1997-12-18 | Yeda Research And Development Co. Ltd. | Human monoclonal antibodies to the hepatitis b surface antigen |
| US20070027099A1 (en) * | 2003-05-19 | 2007-02-01 | Lin Marie C | Gene therapy of HBV infection via adeno-associated viral vector mediated long term expression of small hairpin RNA (shRNA) |
| WO2011047312A1 (en) * | 2009-10-16 | 2011-04-21 | Glaxo Group Limited | Hbv antisense inhibitors |
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