AU2013292266B2 - Cell based quality control bioassays for nutriceutical and medicinal products - Google Patents
Cell based quality control bioassays for nutriceutical and medicinal products Download PDFInfo
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- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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| CN107217087B (zh) * | 2016-03-22 | 2019-12-10 | 中国石油化工股份有限公司 | 迅速测量油田污水和成品油中细菌含量的方法 |
| CN115785247B (zh) * | 2022-12-22 | 2025-06-24 | 中国农业大学 | 一种猪流行性腹泻病毒抗性相关蛋白质eif2a及其相关生物材料和应用 |
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| US4318846A (en) | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4757141A (en) | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
| US5091519A (en) | 1986-05-01 | 1992-02-25 | Amoco Corporation | Nucleotide compositions with linking groups |
| US5151507A (en) | 1986-07-02 | 1992-09-29 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
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| US5066580A (en) | 1988-08-31 | 1991-11-19 | Becton Dickinson And Company | Xanthene dyes that emit to the red of fluorescein |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5654419A (en) | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
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| US5847162A (en) | 1996-06-27 | 1998-12-08 | The Perkin Elmer Corporation | 4, 7-Dichlororhodamine dyes |
| US6322901B1 (en) | 1997-11-13 | 2001-11-27 | Massachusetts Institute Of Technology | Highly luminescent color-selective nano-crystalline materials |
| US5990479A (en) | 1997-11-25 | 1999-11-23 | Regents Of The University Of California | Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US6207392B1 (en) | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US6426513B1 (en) | 1998-09-18 | 2002-07-30 | Massachusetts Institute Of Technology | Water-soluble thiol-capped nanocrystals |
| US6251303B1 (en) | 1998-09-18 | 2001-06-26 | Massachusetts Institute Of Technology | Water-soluble fluorescent nanocrystals |
| US6649138B2 (en) | 2000-10-13 | 2003-11-18 | Quantum Dot Corporation | Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media |
| US6576291B2 (en) | 2000-12-08 | 2003-06-10 | Massachusetts Institute Of Technology | Preparation of nanocrystallites |
| ATE556845T1 (de) | 2001-07-20 | 2012-05-15 | Life Technologies Corp | Lumineszierende nanopartikel und ihre herstellung |
| WO2007008221A2 (en) * | 2004-08-10 | 2007-01-18 | President And Fellows Of Harvard College | DETECTION OF PHOSPHORYLATED eIF2α AS A DIAGNOSTIC TEST FOR EFFICIENCY AND SENSITVITY OF TRANSLATION INITIATION INHIBITORS IN THE TREATMENT OF CANCER AND OTHE R PROLIFERATIVE DISEASES |
| WO2008008333A2 (en) * | 2006-07-11 | 2008-01-17 | President And Fellows Of Harvard College | Bioassays for quality control of nutriceuticals that inhibit, upregulate or otherwise modulate translation initiation |
| CA2763589A1 (en) * | 2009-05-28 | 2010-12-02 | President And Fellows Of Harvard College | N,n'-diarylurea compounds and n,n'-diarylthiourea compounds as inhibitors of translation initiation |
| CN101671669B (zh) * | 2009-08-27 | 2012-05-02 | 浙江大学 | 一种肝癌靶向性基因表达元件ae及其应用 |
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| WO2010121131A2 (en) * | 2009-04-17 | 2010-10-21 | President And Fellows Of Harvard College | Quality control bioassays for nutriceutical and medicinal products |
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| CHEN, T. et al., "Chemical genetics identify eIF2a kinase heme-regulated inhibitor as an anticancer target", Nat. Chem. Biol., (2011), Vol. 7, page pp. 610-616 * |
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| CL2014002530A1 (es) | 2015-01-09 |
| KR20150035496A (ko) | 2015-04-06 |
| EP2820418A1 (en) | 2015-01-07 |
| JP6200501B2 (ja) | 2017-09-20 |
| ES2656941T3 (es) | 2018-03-01 |
| MX2014012542A (es) | 2014-11-21 |
| US20150301023A1 (en) | 2015-10-22 |
| NO2912013T3 (enExample) | 2018-03-10 |
| KR102136763B1 (ko) | 2020-08-13 |
| US9952200B2 (en) | 2018-04-24 |
| CA2866175A1 (en) | 2014-01-23 |
| RU2662358C2 (ru) | 2018-07-25 |
| CA2866175C (en) | 2021-04-20 |
| PE20142297A1 (es) | 2014-12-19 |
| PL2820418T3 (pl) | 2018-05-30 |
| EP2820418B1 (en) | 2017-12-06 |
| JP2015524269A (ja) | 2015-08-24 |
| ZA201406653B (en) | 2022-05-25 |
| MA35924B1 (fr) | 2014-12-01 |
| AU2013292266A1 (en) | 2014-09-25 |
| RU2014136408A (ru) | 2016-09-10 |
| CN104641231B (zh) | 2016-09-07 |
| DK2820418T3 (en) | 2018-02-12 |
| CN104641231A (zh) | 2015-05-20 |
| IN2014DN07866A (enExample) | 2015-04-24 |
| MX356147B (es) | 2018-05-15 |
| PT2820418T (pt) | 2018-02-12 |
| CO7151536A2 (es) | 2014-12-29 |
| HUE036166T2 (hu) | 2018-06-28 |
| WO2014015328A1 (en) | 2014-01-23 |
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