PE20142297A1 - Bioensayos con calidad controlada basados en celulas para productos nutriceuticos y medicinales - Google Patents
Bioensayos con calidad controlada basados en celulas para productos nutriceuticos y medicinalesInfo
- Publication number
- PE20142297A1 PE20142297A1 PE2014001438A PE2014001438A PE20142297A1 PE 20142297 A1 PE20142297 A1 PE 20142297A1 PE 2014001438 A PE2014001438 A PE 2014001438A PE 2014001438 A PE2014001438 A PE 2014001438A PE 20142297 A1 PE20142297 A1 PE 20142297A1
- Authority
- PE
- Peru
- Prior art keywords
- cell
- composition
- inhibition
- proliferation
- nutriceutic
- Prior art date
Links
- 238000004166 bioassay Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 abstract 5
- 230000035755 proliferation Effects 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/02—Food
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
REFERIDO A UN METODO PARA DETERMINAR LA POTENCIA DE INHIBICION DEL INICIO DE LA TRADUCCION DE UNA COMPOSICION QUE TIENE UN GRADO DESCONOCIDO DE ACTIVIDAD DE INHIBICION DEL INICIO DE LA TRADUCCION QUE COMPRENDE: A) PONER EN CONTACTO UNA CELULA CON N� DE ACCESO ATCC PTA-13010 CON DICHA COMPOSICION DURANTE UN TIEMPO Y A UNA TEMPERATURA EFICAZ PARA INHIBIR LA PROLIFERACION DE DICHA CELULA; B) PONER EN CONTACTO UNA CELULA CON N� DE ACCESO ATCC PTA-13011 CON DICHA COMPOSICION DURANTE UN TIEMPO Y A UNA TEMPERATURA EFICAZ PARA INHIBIR LA PROLIFERACION DE DICHA CELULA; C) MEDIR EL NIVEL DE INHIBICION DE PROLIFERACION DE DICHA CELULA CON N� DE ACCESO ATCC PTA-13010 Y DICHA CELULA CON N� DE ACCESO ATCC PTA-13011 INDUCIDO POR DICHA COMPOSICION; D) COMPARAR EL NIVEL DE INHIBICION DE PROLIFERACION INDUCIDO POR DICHA COMPOSICION CON EL NIVEL DE INHIBICION DE PROLIFERACION INDUCIDO POR UN ESTANDAR QUE TIENE UNA CANTIDAD CONOCIDA DE DICHA ACTIVIDAD; E) IDENTIFICAR LA COMPOSICION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261674180P | 2012-07-20 | 2012-07-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20142297A1 true PE20142297A1 (es) | 2014-12-19 |
Family
ID=48916225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014001438A PE20142297A1 (es) | 2012-07-20 | 2013-07-22 | Bioensayos con calidad controlada basados en celulas para productos nutriceuticos y medicinales |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9952200B2 (es) |
| EP (1) | EP2820418B1 (es) |
| JP (1) | JP6200501B2 (es) |
| KR (1) | KR102136763B1 (es) |
| CN (1) | CN104641231B (es) |
| AU (1) | AU2013292266B2 (es) |
| CA (1) | CA2866175C (es) |
| CL (1) | CL2014002530A1 (es) |
| CO (1) | CO7151536A2 (es) |
| DK (1) | DK2820418T3 (es) |
| ES (1) | ES2656941T3 (es) |
| HU (1) | HUE036166T2 (es) |
| IN (1) | IN2014DN07866A (es) |
| MA (1) | MA35924B1 (es) |
| MX (1) | MX356147B (es) |
| NO (1) | NO2912013T3 (es) |
| PE (1) | PE20142297A1 (es) |
| PL (1) | PL2820418T3 (es) |
| PT (1) | PT2820418T (es) |
| RU (1) | RU2662358C2 (es) |
| WO (1) | WO2014015328A1 (es) |
| ZA (1) | ZA201406653B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107217087B (zh) * | 2016-03-22 | 2019-12-10 | 中国石油化工股份有限公司 | 迅速测量油田污水和成品油中细菌含量的方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318846A (en) | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4757141A (en) | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
| US5091519A (en) | 1986-05-01 | 1992-02-25 | Amoco Corporation | Nucleotide compositions with linking groups |
| US5151507A (en) | 1986-07-02 | 1992-09-29 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| US4843155A (en) | 1987-11-19 | 1989-06-27 | Piotr Chomczynski | Product and process for isolating RNA |
| US5066580A (en) | 1988-08-31 | 1991-11-19 | Becton Dickinson And Company | Xanthene dyes that emit to the red of fluorescein |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5654419A (en) | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| US5800996A (en) | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
| US5847162A (en) | 1996-06-27 | 1998-12-08 | The Perkin Elmer Corporation | 4, 7-Dichlororhodamine dyes |
| US6322901B1 (en) | 1997-11-13 | 2001-11-27 | Massachusetts Institute Of Technology | Highly luminescent color-selective nano-crystalline materials |
| US6207392B1 (en) | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US5990479A (en) | 1997-11-25 | 1999-11-23 | Regents Of The University Of California | Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US6426513B1 (en) | 1998-09-18 | 2002-07-30 | Massachusetts Institute Of Technology | Water-soluble thiol-capped nanocrystals |
| US6251303B1 (en) | 1998-09-18 | 2001-06-26 | Massachusetts Institute Of Technology | Water-soluble fluorescent nanocrystals |
| US6649138B2 (en) | 2000-10-13 | 2003-11-18 | Quantum Dot Corporation | Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media |
| US6576291B2 (en) | 2000-12-08 | 2003-06-10 | Massachusetts Institute Of Technology | Preparation of nanocrystallites |
| CA2453450A1 (en) | 2001-07-20 | 2003-11-06 | Quantum Dot Corporation | Luminescent nanoparticles and methods for their preparation |
| WO2007008221A2 (en) * | 2004-08-10 | 2007-01-18 | President And Fellows Of Harvard College | DETECTION OF PHOSPHORYLATED eIF2α AS A DIAGNOSTIC TEST FOR EFFICIENCY AND SENSITVITY OF TRANSLATION INITIATION INHIBITORS IN THE TREATMENT OF CANCER AND OTHE R PROLIFERATIVE DISEASES |
| WO2008008333A2 (en) * | 2006-07-11 | 2008-01-17 | President And Fellows Of Harvard College | Bioassays for quality control of nutriceuticals that inhibit, upregulate or otherwise modulate translation initiation |
| KR101674626B1 (ko) * | 2009-04-17 | 2016-11-09 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 영양약학적 및 의약적 산물에 대한 품질 조절 생분석법 |
| AU2010253820A1 (en) * | 2009-05-28 | 2011-12-22 | President And Fellows Of Harvard College | N,N-diarylurea compounds and N,N'-diarylthiourea compounds as inhibitors of translation initiation |
| CN101671669B (zh) * | 2009-08-27 | 2012-05-02 | 浙江大学 | 一种肝癌靶向性基因表达元件ae及其应用 |
-
2013
- 2013-07-22 KR KR1020147026323A patent/KR102136763B1/ko active IP Right Grant
- 2013-07-22 IN IN7866DEN2014 patent/IN2014DN07866A/en unknown
- 2013-07-22 CN CN201380031597.XA patent/CN104641231B/zh not_active Expired - Fee Related
- 2013-07-22 DK DK13745268.6T patent/DK2820418T3/en active
- 2013-07-22 CA CA2866175A patent/CA2866175C/en active Active
- 2013-07-22 HU HUE13745268A patent/HUE036166T2/hu unknown
- 2013-07-22 JP JP2015523300A patent/JP6200501B2/ja not_active Expired - Fee Related
- 2013-07-22 PL PL13745268T patent/PL2820418T3/pl unknown
- 2013-07-22 US US14/382,116 patent/US9952200B2/en active Active
- 2013-07-22 RU RU2014136408A patent/RU2662358C2/ru active
- 2013-07-22 AU AU2013292266A patent/AU2013292266B2/en not_active Ceased
- 2013-07-22 MX MX2014012542A patent/MX356147B/es active IP Right Grant
- 2013-07-22 EP EP13745268.6A patent/EP2820418B1/en active Active
- 2013-07-22 PT PT137452686T patent/PT2820418T/pt unknown
- 2013-07-22 WO PCT/US2013/051433 patent/WO2014015328A1/en active Application Filing
- 2013-07-22 ES ES13745268.6T patent/ES2656941T3/es active Active
- 2013-07-22 PE PE2014001438A patent/PE20142297A1/es active IP Right Grant
- 2013-10-25 NO NO13849263A patent/NO2912013T3/no unknown
-
2014
- 2014-09-04 MA MA37323A patent/MA35924B1/fr unknown
- 2014-09-10 ZA ZA2014/06653A patent/ZA201406653B/en unknown
- 2014-09-19 CO CO14208659A patent/CO7151536A2/es unknown
- 2014-09-24 CL CL2014002530A patent/CL2014002530A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN104641231A (zh) | 2015-05-20 |
| CA2866175C (en) | 2021-04-20 |
| ES2656941T3 (es) | 2018-03-01 |
| PT2820418T (pt) | 2018-02-12 |
| EP2820418B1 (en) | 2017-12-06 |
| ZA201406653B (en) | 2022-05-25 |
| US20150301023A1 (en) | 2015-10-22 |
| RU2014136408A (ru) | 2016-09-10 |
| CA2866175A1 (en) | 2014-01-23 |
| EP2820418A1 (en) | 2015-01-07 |
| DK2820418T3 (en) | 2018-02-12 |
| IN2014DN07866A (es) | 2015-04-24 |
| JP6200501B2 (ja) | 2017-09-20 |
| JP2015524269A (ja) | 2015-08-24 |
| PL2820418T3 (pl) | 2018-05-30 |
| AU2013292266A1 (en) | 2014-09-25 |
| CO7151536A2 (es) | 2014-12-29 |
| HUE036166T2 (hu) | 2018-06-28 |
| KR20150035496A (ko) | 2015-04-06 |
| KR102136763B1 (ko) | 2020-08-13 |
| MX356147B (es) | 2018-05-15 |
| RU2662358C2 (ru) | 2018-07-25 |
| AU2013292266B2 (en) | 2019-01-03 |
| US9952200B2 (en) | 2018-04-24 |
| WO2014015328A1 (en) | 2014-01-23 |
| MX2014012542A (es) | 2014-11-21 |
| MA35924B1 (fr) | 2014-12-01 |
| NO2912013T3 (es) | 2018-03-10 |
| CL2014002530A1 (es) | 2015-01-09 |
| CN104641231B (zh) | 2016-09-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014029933A2 (pt) | aparelho para teste de eletrodo | |
| BR112017007965A2 (pt) | método implantado por computador para inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; aparelho para inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; meio de armazenamento não transitório; programa de computador; kits para medir níveis de expressão de três ou mais genes-alvo da via de sinalização celular de tgf-b em uma amostra de um indivíduo; inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; e uso do kit | |
| BR112017012335A2 (pt) | método, dispositivo e kit para a cultura em massa de células usando uma membrana de poli-imida porosa | |
| BR112014000965B8 (pt) | Método, aparelho e meio de armazenamento não transitório | |
| BR112014019090A8 (pt) | Método e aparelho | |
| BR112017025864A2 (pt) | ?dispositivo para medir aspereza e brilho do cabelo, método para avaliar o estado do cabelo, kit e embalagem? | |
| AR082388A1 (es) | Metodo para identificar un compuesto que tiene un efecto antiarritmico asi como los usos relacionados con el mismo | |
| NZ630026A (en) | Inhibition of the glycine cleavage system for treatment of cancer | |
| UY34800A (es) | Combinaciones farmacéuticas que contienen un inhibidor de 11-beta-hidroxiesteroide dehidrogenasa-1 útil en trastornos metabólicos | |
| DOP2014000098A (es) | 2-tiopirimidinonas | |
| BR112019000811A2 (pt) | métodos de análise de um fluido de contato de substrato e de um substrato em contato com a água industrial, e, uso de imagens digitais de um substrato e resistência de polarização linear | |
| PE20151494A1 (es) | Proceso novedoso para la elaboracion de compuestos para su uso en el tratamiento del cancer | |
| UY34115A (es) | Ensayo de la lisil oxidasa-like 2 y sus métodos de empleo | |
| CL2019000420A1 (es) | Preparación farmacéutica anti-envejecimiento. | |
| BR112017011903A2 (pt) | processo para avaliação do desempenho catalítico de um sólido poroso | |
| CL2022001368A1 (es) | Uso de inhibidores de sglt-2 en el secado de mamíferos no humanos | |
| BR112015025189A2 (pt) | aparelho de processamento e método de medir temperatura de peça de trabalho no aparelho de processamento | |
| BR112013028780A2 (pt) | aparelho de processamento de imagem, método de processamento de imagem, e meio de armazenamento onde um programa é armazenado | |
| BR112016002668A2 (pt) | métodos e kits para prognosticar o risco de ter uma doença ou evento cardiovasculares | |
| PE20142297A1 (es) | Bioensayos con calidad controlada basados en celulas para productos nutriceuticos y medicinales | |
| BR102012033267A2 (pt) | Dispositivo sensor | |
| UY34455A (es) | Formulación oral compleja que comprende ácido graso omega 3 e inhibidor de la hmg-coa reductasa con estabilidad mejorada | |
| MY172155A (en) | Method for assessing cell aging | |
| BR112013029611A2 (pt) | método para determinar uma quantidade de aplicação em função de um estado de desenvolvimento abrangido de uma população de plantas e dispositivo para a realização do método | |
| BR112013029910A2 (pt) | detecção e rastreamento de alvos em uma série de imagens |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |