AU2013262076B2 - Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam - Google Patents
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam Download PDFInfo
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- AU2013262076B2 AU2013262076B2 AU2013262076A AU2013262076A AU2013262076B2 AU 2013262076 B2 AU2013262076 B2 AU 2013262076B2 AU 2013262076 A AU2013262076 A AU 2013262076A AU 2013262076 A AU2013262076 A AU 2013262076A AU 2013262076 B2 AU2013262076 B2 AU 2013262076B2
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- Australia
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- active ingredient
- pharmacologically active
- dosage form
- pharmaceutical dosage
- pain
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003896 | 2012-05-18 | ||
| EP12003896.3 | 2012-05-18 | ||
| PCT/EP2013/001469 WO2013170970A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam |
Publications (2)
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|---|---|
| AU2013262076A1 AU2013262076A1 (en) | 2015-01-22 |
| AU2013262076B2 true AU2013262076B2 (en) | 2017-10-26 |
Family
ID=48470899
Family Applications (1)
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| AU2013262076A Ceased AU2013262076B2 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9308196B2 (https=) |
| EP (1) | EP2849746B1 (https=) |
| JP (1) | JP6116677B2 (https=) |
| CN (2) | CN104302288A (https=) |
| AU (1) | AU2013262076B2 (https=) |
| BR (1) | BR112014028569A2 (https=) |
| CA (1) | CA2873863A1 (https=) |
| CY (1) | CY1119824T1 (https=) |
| DK (1) | DK2849746T3 (https=) |
| EA (1) | EA026719B1 (https=) |
| ES (1) | ES2659948T3 (https=) |
| HR (1) | HRP20171843T1 (https=) |
| HU (1) | HUE035122T2 (https=) |
| IL (1) | IL235652B (https=) |
| LT (1) | LT2849746T (https=) |
| MX (1) | MX354685B (https=) |
| NO (1) | NO2849746T3 (https=) |
| PL (1) | PL2849746T3 (https=) |
| PT (1) | PT2849746T (https=) |
| RS (1) | RS56830B1 (https=) |
| SI (1) | SI2849746T1 (https=) |
| WO (1) | WO2013170970A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6673924B2 (ja) | 2015-01-23 | 2020-03-25 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 肝機能障害および／または腎機能障害を有する対象における疼痛を治療するためのセブラノパドール |
| JP7373904B2 (ja) | 2016-02-29 | 2023-11-06 | パーク・セラピューティクス・インコーポレイテッド | セブラノパドールの滴定 |
| GB202405898D0 (en) * | 2024-04-26 | 2024-06-12 | Univ Surrey | Mycobacterial infections |
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| KR20130097173A (ko) * | 2010-08-04 | 2013-09-02 | 그뤼넨탈 게엠베하 | 신경병증성 통증을 치료하기 위한 ６’플루오로（Ｎ메틸 또는 Ｎ，Ｎ디메틸）４페닐４’，９’디하이드로３’Ｈ스피로[사이클로헥산１，１’피라노[３，４，ｂ]인돌]４아민을 포함하는 약제학적 투여형 |
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-
2013
- 2013-05-13 US US13/892,362 patent/US9308196B2/en active Active
- 2013-05-16 AU AU2013262076A patent/AU2013262076B2/en not_active Ceased
- 2013-05-16 SI SI201330919T patent/SI2849746T1/en unknown
- 2013-05-16 LT LTEP13724168.3T patent/LT2849746T/lt unknown
- 2013-05-16 MX MX2014012862A patent/MX354685B/es active IP Right Grant
- 2013-05-16 HU HUE13724168A patent/HUE035122T2/en unknown
- 2013-05-16 JP JP2015511956A patent/JP6116677B2/ja active Active
- 2013-05-16 EP EP13724168.3A patent/EP2849746B1/en not_active Not-in-force
- 2013-05-16 DK DK13724168.3T patent/DK2849746T3/en active
- 2013-05-16 PL PL13724168T patent/PL2849746T3/pl unknown
- 2013-05-16 BR BR112014028569A patent/BR112014028569A2/pt not_active IP Right Cessation
- 2013-05-16 HR HRP20171843TT patent/HRP20171843T1/hr unknown
- 2013-05-16 RS RS20180128A patent/RS56830B1/sr unknown
- 2013-05-16 CN CN201380025679.3A patent/CN104302288A/zh active Pending
- 2013-05-16 NO NO13724168A patent/NO2849746T3/no unknown
- 2013-05-16 ES ES13724168.3T patent/ES2659948T3/es active Active
- 2013-05-16 EA EA201401265A patent/EA026719B1/ru not_active IP Right Cessation
- 2013-05-16 CA CA2873863A patent/CA2873863A1/en not_active Abandoned
- 2013-05-16 CN CN201810667716.5A patent/CN108451956A/zh active Pending
- 2013-05-16 WO PCT/EP2013/001469 patent/WO2013170970A1/en not_active Ceased
- 2013-05-16 PT PT137241683T patent/PT2849746T/pt unknown
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2014
- 2014-11-12 IL IL235652A patent/IL235652B/en active IP Right Grant
-
2018
- 2018-01-24 CY CY20181100090T patent/CY1119824T1/el unknown
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| US7700579B2 (en) * | 2002-06-17 | 2010-04-20 | Chiesi Farmaceutici S.P.A. | Process for the preparation of piroxicam: b-cyclodextrin inclusion compounds |
| US20110319440A1 (en) * | 2002-11-11 | 2011-12-29 | Gruenenthal Gmbh | Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds |
| US20100297252A1 (en) * | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| US20080125475A1 (en) * | 2006-09-29 | 2008-05-29 | Grunenthal Gmbh | Mixed ORL1/mu-agonists for the treatment of pain |
| CN101327193A (zh) * | 2008-06-20 | 2008-12-24 | 海南锦瑞制药有限公司 | 一种氯诺昔康冻干粉针剂及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK2849746T3 (en) | 2017-12-04 |
| SI2849746T1 (en) | 2018-02-28 |
| PT2849746T (pt) | 2018-02-22 |
| MX354685B (es) | 2018-03-15 |
| HK1204939A1 (en) | 2015-12-11 |
| CN104302288A (zh) | 2015-01-21 |
| CN108451956A (zh) | 2018-08-28 |
| PL2849746T3 (pl) | 2018-04-30 |
| JP2015516450A (ja) | 2015-06-11 |
| US9308196B2 (en) | 2016-04-12 |
| MX2014012862A (es) | 2015-01-19 |
| EP2849746B1 (en) | 2017-11-15 |
| EA201401265A1 (ru) | 2015-05-29 |
| BR112014028569A2 (pt) | 2017-06-27 |
| IL235652B (en) | 2018-08-30 |
| CY1119824T1 (el) | 2018-06-27 |
| RS56830B1 (sr) | 2018-04-30 |
| AU2013262076A1 (en) | 2015-01-22 |
| NO2849746T3 (https=) | 2018-04-14 |
| EA026719B1 (ru) | 2017-05-31 |
| EP2849746A1 (en) | 2015-03-25 |
| WO2013170970A1 (en) | 2013-11-21 |
| US20130310371A1 (en) | 2013-11-21 |
| CA2873863A1 (en) | 2013-11-21 |
| ES2659948T3 (es) | 2018-03-20 |
| IL235652A0 (en) | 2015-01-29 |
| JP6116677B2 (ja) | 2017-04-19 |
| HRP20171843T1 (hr) | 2018-01-12 |
| HUE035122T2 (en) | 2018-05-02 |
| LT2849746T (lt) | 2018-02-12 |
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