AU2012331034B2 - A liquid enzyme formulation and a process for its preparation - Google Patents

A liquid enzyme formulation and a process for its preparation Download PDF

Info

Publication number
AU2012331034B2
AU2012331034B2 AU2012331034A AU2012331034A AU2012331034B2 AU 2012331034 B2 AU2012331034 B2 AU 2012331034B2 AU 2012331034 A AU2012331034 A AU 2012331034A AU 2012331034 A AU2012331034 A AU 2012331034A AU 2012331034 B2 AU2012331034 B2 AU 2012331034B2
Authority
AU
Australia
Prior art keywords
transglutaminase
enzyme
formulation
suspension
polyol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2012331034A
Other languages
English (en)
Other versions
AU2012331034A1 (en
Inventor
Kai HOTAKAINEN
Paivi Myllarinen
Kirsi Rajakari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valio Oy
Original Assignee
Valio Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valio Oy filed Critical Valio Oy
Publication of AU2012331034A1 publication Critical patent/AU2012331034A1/en
Application granted granted Critical
Publication of AU2012331034B2 publication Critical patent/AU2012331034B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0059—Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0061—Laccase (1.10.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03001—Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03002—Laccase (1.10.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/02—Aminoacyltransferases (2.3.2)
    • C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01043—Peptidyl-glutaminase (3.5.1.43)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
AU2012331034A 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation Active AU2012331034B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20116074A FI126442B (en) 2011-11-01 2011-11-01 Liquid enzyme preparation and process for its preparation
FI20116074 2011-11-01
PCT/FI2012/051048 WO2013064736A1 (en) 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation

Publications (2)

Publication Number Publication Date
AU2012331034A1 AU2012331034A1 (en) 2014-06-26
AU2012331034B2 true AU2012331034B2 (en) 2017-10-19

Family

ID=47215584

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012331034A Active AU2012331034B2 (en) 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation

Country Status (19)

Country Link
US (1) US20140287098A1 (cg-RX-API-DMAC7.html)
EP (1) EP2773753B1 (cg-RX-API-DMAC7.html)
JP (1) JP6297979B2 (cg-RX-API-DMAC7.html)
KR (1) KR101998182B1 (cg-RX-API-DMAC7.html)
CN (2) CN104024406A (cg-RX-API-DMAC7.html)
AU (1) AU2012331034B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014010222B1 (cg-RX-API-DMAC7.html)
CA (1) CA2853711C (cg-RX-API-DMAC7.html)
CL (1) CL2014001100A1 (cg-RX-API-DMAC7.html)
DK (1) DK2773753T3 (cg-RX-API-DMAC7.html)
ES (1) ES2697675T3 (cg-RX-API-DMAC7.html)
FI (1) FI126442B (cg-RX-API-DMAC7.html)
IL (1) IL232356B (cg-RX-API-DMAC7.html)
IN (1) IN2014MN00968A (cg-RX-API-DMAC7.html)
MX (1) MX356454B (cg-RX-API-DMAC7.html)
PL (1) PL2773753T3 (cg-RX-API-DMAC7.html)
RU (1) RU2668396C2 (cg-RX-API-DMAC7.html)
WO (1) WO2013064736A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201403965B (cg-RX-API-DMAC7.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2913045B1 (en) 2012-10-17 2019-04-10 Ajinomoto Co., Inc. Cosmetic composition
CN107177582B (zh) * 2016-02-16 2018-05-22 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
EP3435781B8 (en) 2016-04-01 2025-08-13 Oatly AB Process for producing non-dairy food product of enhanced viscosity
CN105852053A (zh) * 2016-04-20 2016-08-17 上海青瑞食品科技有限公司 一种液体酶制剂在食品质构改良中的应用
JP6787563B2 (ja) * 2016-06-30 2020-11-18 千葉製粉株式会社 接着成形食品の製造方法、接着成形食品用の接着成分分散液、および、接着成形食品
CN107897533A (zh) * 2017-12-10 2018-04-13 济南诺能生物工程有限公司 一种单胃动物液体复合酶的制备方法
JP7501357B2 (ja) 2018-03-23 2024-06-18 味の素株式会社 トランスグルタミナーゼを含有する液体製剤
JPWO2021187510A1 (cg-RX-API-DMAC7.html) * 2020-03-17 2021-09-23
KR20230010681A (ko) * 2020-05-13 2023-01-19 큐리 컴퍼니 인코포레이티드 트랜스글루타미나제 변이체 및 그의 사용 적용분야
JPWO2022054880A1 (cg-RX-API-DMAC7.html) * 2020-09-10 2022-03-17
US20230329292A1 (en) * 2020-09-10 2023-10-19 Amano Enzyme Inc. Tofu production method
WO2022118914A1 (ja) * 2020-12-04 2022-06-09 天野エンザイム株式会社 液体酵素製剤
CN117940561A (zh) 2021-10-04 2024-04-26 天野酶制品株式会社 液态转谷氨酰胺酶酶制剂
US20250313822A1 (en) 2022-05-23 2025-10-09 Amano Enzyme Inc. Liquid enzyme preparation
CN115380981A (zh) * 2022-08-09 2022-11-25 武汉新华扬生物股份有限公司 一种用于冷萃咖啡的复配酶制剂及其应用方法
EP4428218A1 (en) * 2023-03-07 2024-09-11 SkyLab AG Biodegradable transglutaminase-based detergent composition for regeneration of microdamage and regulation of elasticity of delicate fiber
WO2024257876A1 (ja) * 2023-06-14 2024-12-19 天野エンザイム株式会社 液体酵素製剤
WO2025046141A1 (en) 2023-09-01 2025-03-06 Novozymes A/S Stabilized liquid deamidase compositions
WO2025056701A1 (en) * 2023-09-13 2025-03-20 Novozymes A/S Stabilized deamidase compositions
WO2025233391A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (en) * 2024-05-13 2025-11-19 Novozymes A/S Stabilized liquid deamidase compositions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340734A (en) * 1992-11-25 1994-08-23 Biosource Genetics Corporation Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
US20030190399A1 (en) * 2000-09-28 2003-10-09 Schooneveld-Bergmans Margot Elisabeth Francoise Liquid bread improving compositions
EP1543732A1 (en) * 2002-09-26 2005-06-22 Ajinomoto Co., Inc. Enzyme preparation and process for producing food using the same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665280B2 (ja) 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
PL177022B1 (pl) * 1994-04-18 1999-09-30 Gist Brocades Bv Trwała emulsja typu woda w oleju
ATE329014T1 (de) 1994-08-26 2006-06-15 Novozymes As Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung
CN1167791C (zh) * 1997-03-12 2004-09-22 诺沃奇梅兹有限公司 包含漆酶的耐贮存液体制剂
US20030219853A1 (en) * 2002-03-01 2003-11-27 Szu-Yi Chou Method of cross-linking a compound
JP2005034078A (ja) * 2003-07-17 2005-02-10 Rengo Co Ltd タンパク質安定化剤
EP1836897A1 (en) * 2006-03-22 2007-09-26 Nestec S.A. A solid product comprising oil-droplets
GB2438287A (en) * 2006-05-19 2007-11-21 Norbrook Lab Ltd Stable aqueous suspension
CN101945995B (zh) * 2008-02-13 2013-06-12 天野酶株式会社 稳定型转谷氨酰胺酶及其制造法
US20110064847A1 (en) * 2008-03-14 2011-03-17 Ajinomoto Co., Inc. Method of denaturing protein with enzymes
WO2009152176A2 (en) * 2008-06-09 2009-12-17 Danisco Us Inc., Genencor Division Recovery of insoluble enzyme from fermentation broth and formulation of insoluble enzyme

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340734A (en) * 1992-11-25 1994-08-23 Biosource Genetics Corporation Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
US20030190399A1 (en) * 2000-09-28 2003-10-09 Schooneveld-Bergmans Margot Elisabeth Francoise Liquid bread improving compositions
EP1543732A1 (en) * 2002-09-26 2005-06-22 Ajinomoto Co., Inc. Enzyme preparation and process for producing food using the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BRADBURY, S., et al., "Glycerol as an Enzyme-Stabilizing Agent: Effects on Aldehyde Dehydrogenase", PNAS (1972), vol 69, no. 9, pages 2373-2376 *
YU, Y.-U., et al., "Overproduction of soluble recombinant transglutaminase from Streptomyces netropsis in Escheruchia coli", Appi Microbiol Biotechnol (2008), vol 81, no. 3, pages 523-532 *

Also Published As

Publication number Publication date
BR112014010222A8 (pt) 2017-06-20
FI126442B (en) 2016-12-15
MX356454B (es) 2018-05-30
US20140287098A1 (en) 2014-09-25
JP2014532421A (ja) 2014-12-08
MX2014005128A (es) 2014-07-09
BR112014010222A2 (pt) 2017-06-13
AU2012331034A1 (en) 2014-06-26
CL2014001100A1 (es) 2014-09-05
CN108676782A (zh) 2018-10-19
KR101998182B1 (ko) 2019-10-01
KR20140096090A (ko) 2014-08-04
ES2697675T3 (es) 2019-01-25
ZA201403965B (en) 2015-05-27
PL2773753T3 (pl) 2019-03-29
JP6297979B2 (ja) 2018-03-20
CA2853711C (en) 2019-11-26
DK2773753T3 (en) 2018-12-10
RU2014121318A (ru) 2015-12-10
IL232356B (en) 2019-03-31
RU2668396C2 (ru) 2018-09-28
IL232356A0 (en) 2014-06-30
EP2773753B1 (en) 2018-10-17
CN104024406A (zh) 2014-09-03
BR112014010222B1 (pt) 2022-04-12
WO2013064736A1 (en) 2013-05-10
IN2014MN00968A (cg-RX-API-DMAC7.html) 2015-04-24
EP2773753A1 (en) 2014-09-10
FI20116074L (fi) 2013-05-02
CA2853711A1 (en) 2013-05-10

Similar Documents

Publication Publication Date Title
AU2012331034B2 (en) A liquid enzyme formulation and a process for its preparation
JP3651003B2 (ja) 安定化されたトランスグルタミナーゼ及びそれを含む酵素製剤
US8043639B2 (en) Process for producing whey protein-enriched fermented milk of agitated type
JP6412827B2 (ja) 生物によって産生される風味の急速生成および使用のための方法
JP5627022B2 (ja) 低脂肪又は無脂肪ヨーグルト及びその製造方法
JP2009516522A (ja) 調製物のテクスチュアを変更する方法
EP4212626A1 (en) Method of producing processed protein
US20130022710A1 (en) Ice cream or ice cream-like product and method for producing same
EP3262946B1 (en) Cheese production method and preparation for cheese reformulation
WO2018079758A1 (ja) 発酵乳製品の製造方法及び酵素含有組成物
JP5561579B2 (ja) 納豆及びその製造方法
Hiller et al. Optimization of enzymatic oligomerization reaction conditions for three milk protein products via ceteris-paribus approach
JP2023507371A (ja) グリシンによるオキシダーゼの安定化
IANNIELLO et al. Growth performances and production of metabolites

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)