AU2012275346B2 - Predictive biomarker of survival in the treatment of renal cell carcinoma - Google Patents
Predictive biomarker of survival in the treatment of renal cell carcinoma Download PDFInfo
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| WO2016209972A1 (en) * | 2015-06-26 | 2016-12-29 | Amgen Inc. | Biomarker of survival in the treatment of renal cell carcinoma with a vegfr inhibitor and an ang2 inhibitor |
| JP6853789B2 (ja) * | 2015-12-24 | 2021-03-31 | 公益財団法人がん研究会 | マルチキナーゼ阻害剤の有効性と安全性を予測する検査方法、検査キット、及びバイオマーカー |
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| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
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| US5013653A (en) | 1987-03-20 | 1991-05-07 | Creative Biomolecules, Inc. | Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage |
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| US5871723A (en) | 1995-06-06 | 1999-02-16 | The Regent Of The University Of Michigan | CXC chemokines as regulators of angiogenesis |
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| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| US7138370B2 (en) | 2001-10-11 | 2006-11-21 | Amgen Inc. | Specific binding agents of human angiopoietin-2 |
| JP5179373B2 (ja) * | 2005-12-15 | 2013-04-10 | アストラゼネカ アクチボラグ | 癌を治療するためのアンジオポエチン−２アンタゴニストとＶＥＧＦ−Ａ、ＫＤＲ、及び／又はＦｌｔ１アンタゴニストの組合せ |
| JO3324B1 (ar) | 2006-04-21 | 2019-03-13 | Amgen Inc | مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية |
| KR20120043028A (ko) | 2006-11-10 | 2012-05-03 | 씨오브이엑스 테크놀로지스 아일랜드 리미티드 | 혈관 신생 억제 화합물 |
| WO2008115714A2 (en) * | 2007-03-20 | 2008-09-25 | Apocell, Inc. | Evaluating rtk target drugs |
| JP5699075B2 (ja) * | 2008-05-14 | 2015-04-08 | アムジエン・インコーポレーテツド | 癌の治療のためのｖｅｇｆ（ｒ）阻害剤および肝細胞増殖因子（ｃ−ｍｅｔ）阻害剤との組合せ |
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- 2012-06-28 EP EP12737394.2A patent/EP2726088B1/en active Active
- 2012-06-28 US US14/127,157 patent/US9151761B2/en active Active
- 2012-06-28 CA CA2840212A patent/CA2840212A1/en not_active Abandoned
- 2012-06-28 WO PCT/US2012/044673 patent/WO2013003606A1/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007089445A2 (en) * | 2006-01-27 | 2007-08-09 | Amgen Inc. | Ang2 and vegf inhibitor combinations |
Non-Patent Citations (4)
| Title |
|---|
| DePRIMO, S.E. et al. J Transl Med. 2007; 5: 32. Published online 2007 Jul 2. * |
| MOTZER, R.J. et al. J Clin Oncol. 2006 Jan 1;24(1):16-24. Epub 2005 Dec 5. * |
| NCT00467025 Clinical Trial by Amgen: "AMG 386, 20060159 Phase 2, RCC 1st Line in Combination With Sorafenib", ClinicalTrials.gov website, 26 April 2007. Retrieved from the internet: https://clinicaltrials.gov on the 11 May 2015. * |
| RINI, B.I. "Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma." J Clin Oncol. 2008 Aug 1;26(22):3743-8. * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6069312B2 (ja) | 2017-02-01 |
| MX358726B (es) | 2018-09-03 |
| CA2840212A1 (en) | 2013-01-03 |
| EP2726088A1 (en) | 2014-05-07 |
| EP2726088B1 (en) | 2019-01-02 |
| JP2014521070A (ja) | 2014-08-25 |
| WO2013003606A1 (en) | 2013-01-03 |
| AU2012275346A1 (en) | 2013-12-19 |
| MX2013015146A (es) | 2014-03-27 |
| US9151761B2 (en) | 2015-10-06 |
| US20140348824A1 (en) | 2014-11-27 |
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