AU2012268441B2 - ShK-based pharmaceutical compositions and methods of manufacturing and using the same - Google Patents
ShK-based pharmaceutical compositions and methods of manufacturing and using the same Download PDFInfo
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- AU2012268441B2 AU2012268441B2 AU2012268441A AU2012268441A AU2012268441B2 AU 2012268441 B2 AU2012268441 B2 AU 2012268441B2 AU 2012268441 A AU2012268441 A AU 2012268441A AU 2012268441 A AU2012268441 A AU 2012268441A AU 2012268441 B2 AU2012268441 B2 AU 2012268441B2
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| PCT/US2012/040857 WO2012170392A2 (en) | 2011-06-06 | 2012-06-05 | Shk-based pharmaceutical compositions and methods of manufacturing and using the same |
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| WO2012170392A2 (en) | 2011-06-06 | 2012-12-13 | Kineta One, Llc | Shk-based pharmaceutical compositions and methods of manufacturing and using the same |
| EP3024472A4 (en) * | 2013-07-22 | 2017-06-28 | Kineta One, LLC | Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof |
| JP6847828B2 (ja) * | 2014-08-15 | 2021-03-24 | モナッシュ ユニバーシティ | 新規なカリウムチャネルブロッカー及び自己免疫疾患の治療におけるそれらの使用 |
| LT3288379T (lt) | 2015-05-01 | 2022-02-25 | Onl Therapeutics, Inc. | Peptidų kompozicijos ir naudojimo būdai |
| KR102533290B1 (ko) * | 2022-04-14 | 2023-05-16 | 한국해양과학기술원 | 전압개폐 칼륨이온채널 억제 활성능을 갖는 펩타이드 |
| KR102553070B1 (ko) * | 2022-06-16 | 2023-07-07 | 한국해양과학기술원 | 전압개폐 칼륨이온채널 억제 활성능을 갖는 작은상자해파리 기원 펩타이드 |
| WO2026003546A1 (en) | 2024-06-27 | 2026-01-02 | Vrg Miniprotein Zrt | Potassium ion kv1.3 channel inhibitors |
Citations (2)
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|---|---|---|---|---|
| US20080221024A1 (en) * | 2004-10-07 | 2008-09-11 | Chandy George K | Analogs of Shk Toxin and Their Uses in Selective Inhibittion of Kv1. 3 Potassium Channels |
| WO2010108154A2 (en) * | 2009-03-20 | 2010-09-23 | Amgen Inc. | Selective and potent peptide inhibitors of kv1.3 |
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| US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4353888A (en) | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
| US4883666A (en) | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
| US5158881A (en) | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| DE3829766A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Verfahren zur herstellung von membranen |
| DE3829752A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration |
| US5084350A (en) | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| CA2109085C (en) | 1991-04-25 | 2003-03-11 | Keith E. Dionne | Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products |
| ATE218893T1 (de) | 1993-08-12 | 2002-06-15 | Neurotech Sa | Biokompatible immunoisolatorische kapseln, die genetisch veränderte zellen enthalten |
| AU7093396A (en) * | 1995-09-07 | 1997-03-27 | Elan Medical Technologies Limited | Medicament conversion system |
| WO1998023639A2 (en) * | 1996-11-27 | 1998-06-04 | University Of Florida | ShK TOXIN COMPOSITIONS AND METHODS OF USE |
| WO1999013895A1 (en) | 1997-09-17 | 1999-03-25 | University Of Florida | Polypeptide compositions that inhibit potassium channel activity and uses therefor |
| EP0953576B1 (en) * | 1998-04-30 | 2005-11-02 | Curis, Inc. | Active hedgehog protein conjugate, process for its production and use |
| US7833979B2 (en) | 2005-04-22 | 2010-11-16 | Amgen Inc. | Toxin peptide therapeutic agents |
| EP1904130B1 (en) | 2005-06-21 | 2016-03-30 | Eli Lilly And Company | Needled pharmaceutical delivery device with triggered automatic needle insertion and manually controlled pharmaceutical injection |
| US20110163469A1 (en) | 2005-12-16 | 2011-07-07 | Massachusetts Institute Of Technology | High-throughput fabrication of microparticles |
| WO2009021289A1 (en) | 2007-08-14 | 2009-02-19 | The Walter And Eliza Hall Institute Of Medical Research | Potassium channel inhibitors |
| US8722079B2 (en) | 2008-04-18 | 2014-05-13 | Warsaw Orthopedic, Inc. | Methods for treating conditions such as dystonia and post-stroke spasticity with clonidine |
| WO2012170392A2 (en) | 2011-06-06 | 2012-12-13 | Kineta One, Llc | Shk-based pharmaceutical compositions and methods of manufacturing and using the same |
| IN2014CN03333A (https=) * | 2011-10-03 | 2015-07-03 | Univ California | |
| US20160338967A1 (en) * | 2013-12-23 | 2016-11-24 | Kineta One, Llc | Sustained release depot formulations of therapeutic proteins, and uses thereof |
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2012
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080221024A1 (en) * | 2004-10-07 | 2008-09-11 | Chandy George K | Analogs of Shk Toxin and Their Uses in Selective Inhibittion of Kv1. 3 Potassium Channels |
| WO2010108154A2 (en) * | 2009-03-20 | 2010-09-23 | Amgen Inc. | Selective and potent peptide inhibitors of kv1.3 |
Non-Patent Citations (1)
| Title |
|---|
| BEETON CHRISTINE ET AL: MOLECULAR PHARMACOLOGY, 2005, Vol. 67, No. 4, pages 1369-1381 * |
Also Published As
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| US9878058B2 (en) | 2018-01-30 |
| CN103687608B (zh) | 2018-06-26 |
| RU2637085C2 (ru) | 2017-11-29 |
| EP3263123A2 (en) | 2018-01-03 |
| US20140221271A1 (en) | 2014-08-07 |
| WO2012170392A3 (en) | 2013-03-14 |
| SG10201604468QA (en) | 2016-07-28 |
| JP2014517005A (ja) | 2014-07-17 |
| US9381261B2 (en) | 2016-07-05 |
| JP2018008955A (ja) | 2018-01-18 |
| KR20140038501A (ko) | 2014-03-28 |
| AU2016208422A1 (en) | 2016-08-18 |
| JP6250536B2 (ja) | 2017-12-20 |
| EP2717899A2 (en) | 2014-04-16 |
| US20160045627A1 (en) | 2016-02-18 |
| CN103687608A (zh) | 2014-03-26 |
| TWI535455B (zh) | 2016-06-01 |
| RU2013157823A (ru) | 2015-07-20 |
| MX2013014401A (es) | 2014-09-25 |
| MX351353B (es) | 2017-10-11 |
| EP2717899A4 (en) | 2015-07-29 |
| US20160331847A1 (en) | 2016-11-17 |
| BR112013031370A2 (pt) | 2016-11-29 |
| SG195302A1 (en) | 2013-12-30 |
| EP3263123A3 (en) | 2018-05-16 |
| TW201300133A (zh) | 2013-01-01 |
| TW201542231A (zh) | 2015-11-16 |
| CA2838474A1 (en) | 2012-12-13 |
| AU2012268441A1 (en) | 2013-12-19 |
| WO2012170392A2 (en) | 2012-12-13 |
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