AU2012236106B2 - Treatment for dermatological pathologies - Google Patents

Treatment for dermatological pathologies Download PDF

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Publication number
AU2012236106B2
AU2012236106B2 AU2012236106A AU2012236106A AU2012236106B2 AU 2012236106 B2 AU2012236106 B2 AU 2012236106B2 AU 2012236106 A AU2012236106 A AU 2012236106A AU 2012236106 A AU2012236106 A AU 2012236106A AU 2012236106 B2 AU2012236106 B2 AU 2012236106B2
Authority
AU
Australia
Prior art keywords
human
subject
antibody
mabpl
vulgaris
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2012236106A
Other languages
English (en)
Other versions
AU2012236106A1 (en
Inventor
John Simard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of AU2012236106A1 publication Critical patent/AU2012236106A1/en
Application granted granted Critical
Publication of AU2012236106B2 publication Critical patent/AU2012236106B2/en
Priority to AU2017201201A priority Critical patent/AU2017201201B2/en
Assigned to XBIOTECH INC. reassignment XBIOTECH INC. Request to Amend Deed and Register Assignors: XBIOTECH, INC.
Assigned to JANSSEN BIOTECH, INC. reassignment JANSSEN BIOTECH, INC. Request for Assignment Assignors: XBIOTECH INC.
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2012236106A 2011-04-01 2012-04-02 Treatment for dermatological pathologies Ceased AU2012236106B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2017201201A AU2017201201B2 (en) 2011-04-01 2017-02-22 Treatment for dermatological pathologies

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161470538P 2011-04-01 2011-04-01
US61/470,538 2011-04-01
PCT/US2012/031803 WO2012135812A2 (en) 2011-04-01 2012-04-02 Treatment for dermatological pathologies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2017201201A Division AU2017201201B2 (en) 2011-04-01 2017-02-22 Treatment for dermatological pathologies

Publications (2)

Publication Number Publication Date
AU2012236106A1 AU2012236106A1 (en) 2013-09-26
AU2012236106B2 true AU2012236106B2 (en) 2016-12-08

Family

ID=46927554

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2012236106A Ceased AU2012236106B2 (en) 2011-04-01 2012-04-02 Treatment for dermatological pathologies
AU2017201201A Ceased AU2017201201B2 (en) 2011-04-01 2017-02-22 Treatment for dermatological pathologies

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2017201201A Ceased AU2017201201B2 (en) 2011-04-01 2017-02-22 Treatment for dermatological pathologies

Country Status (11)

Country Link
US (2) US20120251548A1 (https=)
EP (2) EP3417879A1 (https=)
JP (2) JP6062918B2 (https=)
KR (3) KR102326482B1 (https=)
CN (2) CN110201157A (https=)
AU (2) AU2012236106B2 (https=)
CA (1) CA2831126C (https=)
DK (1) DK2694107T3 (https=)
ES (1) ES2697056T3 (https=)
PT (1) PT2694107T (https=)
WO (1) WO2012135812A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102167261B1 (ko) 2010-06-18 2020-10-20 엑스바이오테크, 인크. 관절염 치료
US10294296B2 (en) 2010-08-23 2019-05-21 Xbiotech, Inc. Treatment for neoplastic diseases
US9724409B2 (en) 2011-04-01 2017-08-08 Xbiotech, Inc. Treatment of inflammatory skin disease
JP6062918B2 (ja) * 2011-04-01 2017-01-18 エックスバイオテク, インコーポレイテッドXbiotech, Inc. 皮膚科的病理の治療
ES2695102T3 (es) 2011-09-23 2019-01-02 Xbiotech Inc Tratamiento para la caquexia
US9545441B2 (en) 2012-09-18 2017-01-17 Xbiotech, Inc. Treatment of diabetes
AU2013327498B2 (en) * 2012-10-04 2018-06-28 Janssen Biotech, Inc. Treatment of psychiatric conditions
CA3053231A1 (en) * 2017-02-16 2018-08-23 Xbiotech Inc. Treatment of hidradenitis suppurativa
US20230235042A1 (en) * 2020-04-16 2023-07-27 Janssen Biotech, Inc. Treatment of hidradenitis suppurativa
CA3095676A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin 1 alpha (il-1a)
CA3095679A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleuken 1 alpha (il-1a)
CA3095675A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin 1 alpha (il-1a)
CA3095740A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin alpha (il-1a)

Citations (4)

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Publication number Priority date Publication date Assignee Title
WO1995024917A1 (en) * 1994-03-15 1995-09-21 Unilever Plc Skin treatment composition
US5959085A (en) * 1993-11-23 1999-09-28 Schering Corporation Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
US20090298096A1 (en) * 2008-05-30 2009-12-03 Xbiotech, Inc. Interleukin-1 alpha ABS and methods of use
US20100221179A1 (en) * 2009-01-29 2010-09-02 Abbott Laboratories IL-1 Binding Proteins

Family Cites Families (17)

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CH652145A5 (de) 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US7192584B2 (en) * 1991-03-18 2007-03-20 Centocor, Inc. Methods of treating psoriasis with anti-TNF antibodies
CA2147151A1 (en) 1992-10-14 1994-04-28 Robert A. Snow Therapeutic and diagnostic imaging compositions and methods
US5945576A (en) * 1996-04-05 1999-08-31 Brigham & Women's Hospital, Inc. Mouse model of psoriasis
JPWO2002033094A1 (ja) 2000-10-19 2004-10-21 協和醗酵工業株式会社 Ｖｐｌｆの活性を阻害する抗体
JP4450644B2 (ja) 2003-03-03 2010-04-14 日本化薬株式会社 Ａｍｆ類を有効成分とする医薬製剤
WO2006001967A2 (en) 2004-05-25 2006-01-05 Sloan-Kettering Institute For Cancer Research Migrastatin analogs in the treatment of cancer
US20050276807A1 (en) * 2004-06-15 2005-12-15 Advanced Biotherapy, Inc. Treatment of acne
US7612181B2 (en) * 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
US20090215992A1 (en) 2005-08-19 2009-08-27 Chengbin Wu Dual variable domain immunoglobulin and uses thereof
ES2567402T3 (es) 2006-05-30 2016-04-22 Genentech, Inc. Anticuerpos anti CD22, sus inmunoconjugados y usos de los mismos
WO2008082651A2 (en) * 2006-12-29 2008-07-10 Abbott Laboratories Dual-specific il-1a/ il-1b antibodies
AU2009291536B2 (en) * 2008-09-12 2012-08-16 Xbiotech Inc. Targeting pathogenic monocytes
JP5866130B2 (ja) * 2010-09-10 2016-02-17 アペクシジェン， インコーポレイテッド 抗ＩＬ−１β抗体およびその使用方法
JP6062918B2 (ja) * 2011-04-01 2017-01-18 エックスバイオテク, インコーポレイテッドXbiotech, Inc. 皮膚科的病理の治療
JP5812669B2 (ja) 2011-04-27 2015-11-17 キヤノン株式会社 画像処理装置および画像処理方法およびコンピュータプログラム。

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5959085A (en) * 1993-11-23 1999-09-28 Schering Corporation Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
WO1995024917A1 (en) * 1994-03-15 1995-09-21 Unilever Plc Skin treatment composition
US20090298096A1 (en) * 2008-05-30 2009-12-03 Xbiotech, Inc. Interleukin-1 alpha ABS and methods of use
US20100221179A1 (en) * 2009-01-29 2010-09-02 Abbott Laboratories IL-1 Binding Proteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GONZALEZ-LOPEZ, M. A. et al British Journal of Dermatology, Vol. 158, No.5, page 1146-1148. 5 May 2008 *

Also Published As

Publication number Publication date
KR102004554B1 (ko) 2019-10-01
JP6453278B2 (ja) 2019-01-16
CN110201157A (zh) 2019-09-06
EP2694107B1 (en) 2018-08-22
CA2831126A1 (en) 2012-10-04
US20120251548A1 (en) 2012-10-04
PT2694107T (pt) 2018-11-27
KR20190090046A (ko) 2019-07-31
KR102326482B1 (ko) 2021-11-17
EP3417879A1 (en) 2018-12-26
ES2697056T3 (es) 2019-01-21
EP2694107A2 (en) 2014-02-12
CN103442733A (zh) 2013-12-11
EP2694107A4 (en) 2014-10-01
CA2831126C (en) 2019-11-12
KR20200145844A (ko) 2020-12-30
DK2694107T3 (en) 2018-12-10
JP6062918B2 (ja) 2017-01-18
AU2017201201A1 (en) 2017-04-06
JP2014509662A (ja) 2014-04-21
KR20140033036A (ko) 2014-03-17
WO2012135812A3 (en) 2013-01-31
JP2017014228A (ja) 2017-01-19
AU2012236106A1 (en) 2013-09-26
US9902769B2 (en) 2018-02-27
WO2012135812A2 (en) 2012-10-04
AU2017201201B2 (en) 2018-12-13
US20160368982A1 (en) 2016-12-22

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: XBIOTECH INC.

Free format text: FORMER NAME(S): XBIOTECH, INC.

PC Assignment registered

Owner name: JANSSEN BIOTECH, INC.

Free format text: FORMER OWNER(S): XBIOTECH INC.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired