AU2012235767B2 - Markers for identifying tumor cells, methods and kit thereof - Google Patents
Markers for identifying tumor cells, methods and kit thereof Download PDFInfo
- Publication number
- AU2012235767B2 AU2012235767B2 AU2012235767A AU2012235767A AU2012235767B2 AU 2012235767 B2 AU2012235767 B2 AU 2012235767B2 AU 2012235767 A AU2012235767 A AU 2012235767A AU 2012235767 A AU2012235767 A AU 2012235767A AU 2012235767 B2 AU2012235767 B2 AU 2012235767B2
- Authority
- AU
- Australia
- Prior art keywords
- combination
- cadherin
- cells
- biological markers
- breast cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2835CH2010 | 2011-03-27 | ||
| IN2835/CHE/2010 | 2011-03-27 | ||
| PCT/IB2012/051427 WO2012131564A1 (en) | 2011-03-27 | 2012-03-26 | Markers for identifying tumor cells, methods and kit thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012235767A1 AU2012235767A1 (en) | 2013-11-07 |
| AU2012235767B2 true AU2012235767B2 (en) | 2016-02-04 |
Family
ID=46877646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012235767A Active AU2012235767B2 (en) | 2011-03-27 | 2012-03-26 | Markers for identifying tumor cells, methods and kit thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8772455B2 (https=) |
| EP (1) | EP2691776A4 (https=) |
| JP (1) | JP2014515821A (https=) |
| KR (1) | KR101621036B1 (https=) |
| CN (1) | CN103562723B (https=) |
| AU (1) | AU2012235767B2 (https=) |
| SG (1) | SG193630A1 (https=) |
| WO (1) | WO2012131564A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9938583B2 (en) | 2013-03-15 | 2018-04-10 | Varian Medical Systems, Inc. | Biomarkers for radiation treatment |
| CN105339390A (zh) * | 2013-04-29 | 2016-02-17 | Ogd2药物 | 靶向o-乙酰化的gd2神经节苷脂作为针对癌症干细胞的新型治疗和诊断策略 |
| JP6841609B2 (ja) | 2015-07-10 | 2021-03-10 | 3スキャン インコーポレイテッド | 組織学的染色の空間的多重化 |
| FR3044680B1 (fr) * | 2015-12-02 | 2017-12-22 | Univ Limoges | Methode de detection de cellules souches cancereuses |
| US10900968B2 (en) * | 2016-05-24 | 2021-01-26 | Oncostem Pte. Ltd. | Method of prognosing and predicting breast cancer recurrence, markers employed therein and kit thereof |
| CN106053172B (zh) * | 2016-06-03 | 2018-10-30 | 浙江世纪康大医疗科技股份有限公司 | 一种edta抗原修复液 |
| US10166406B2 (en) | 2017-02-24 | 2019-01-01 | Varian Medical Systems International Ag | Radiation treatment planning and delivery using collision free regions |
| CN115429881A (zh) * | 2022-09-02 | 2022-12-06 | 中国医学科学院基础医学研究所 | 铁螯合剂治疗β-连环蛋白活化突变的肿瘤 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011113047A2 (en) * | 2010-03-12 | 2011-09-15 | The Johns Hopkins University | Compositions and methods for characterizing breast cancer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005080601A2 (en) * | 2004-02-23 | 2005-09-01 | Erasmus Universiteit Rotterdam | Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling |
| DE602005018789D1 (de) * | 2004-08-10 | 2011-05-26 | Cardiff Biolog Ltd | Verfahren und kit zur prognose von brustkrebs |
| WO2007075672A2 (en) * | 2005-12-23 | 2007-07-05 | Lankenau Institute For Medical Research | Prognostic cancer markers |
| UA110315C2 (uk) * | 2006-09-29 | 2015-12-25 | Oncomed Pharm Inc | Композиція та спосіб лікування раку |
| EA018260B1 (ru) * | 2006-09-29 | 2013-06-28 | Онкомед Фармасьютикалз, Инк. | Антитела к дельта-подобному лиганду 4 человека и их применение |
| US7968169B2 (en) * | 2007-08-07 | 2011-06-28 | The Boeing Company | Compound contoured composite beams and fabrication methods |
| EP2274617A4 (en) * | 2008-04-10 | 2011-11-09 | Massachusetts Inst Technology | METHOD OF DETECTING AND USING MEDIUM-TREATMENT AID ON CANCER STEM CELLS |
| WO2011007853A1 (ja) * | 2009-07-14 | 2011-01-20 | リンク・ジェノミクス株式会社 | 癌特異的アイソフォームに対するモノクローナル抗体 |
-
2012
- 2012-03-26 CN CN201280021095.4A patent/CN103562723B/zh active Active
- 2012-03-26 WO PCT/IB2012/051427 patent/WO2012131564A1/en not_active Ceased
- 2012-03-26 AU AU2012235767A patent/AU2012235767B2/en active Active
- 2012-03-26 SG SG2013072483A patent/SG193630A1/en unknown
- 2012-03-26 KR KR1020137028327A patent/KR101621036B1/ko active Active
- 2012-03-26 JP JP2014501759A patent/JP2014515821A/ja active Pending
- 2012-03-26 EP EP12765275.8A patent/EP2691776A4/en not_active Withdrawn
- 2012-03-27 US US13/431,919 patent/US8772455B2/en active Active
-
2014
- 2014-06-13 US US14/304,432 patent/US20140295459A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011113047A2 (en) * | 2010-03-12 | 2011-09-15 | The Johns Hopkins University | Compositions and methods for characterizing breast cancer |
Non-Patent Citations (2)
| Title |
|---|
| HONETH, G. et al., Breast Cancer Research, 2008, vol. 10, R53 * |
| LIU, Q. et al., Chinese Medical Journal, 2009, vol. 122, pages 2763-2769 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US8772455B2 (en) | 2014-07-08 |
| WO2012131564A1 (en) | 2012-10-04 |
| EP2691776A4 (en) | 2015-04-15 |
| CN103562723B (zh) | 2017-04-26 |
| CN103562723A (zh) | 2014-02-05 |
| EP2691776A1 (en) | 2014-02-05 |
| AU2012235767A1 (en) | 2013-11-07 |
| KR101621036B1 (ko) | 2016-05-13 |
| US20120244556A1 (en) | 2012-09-27 |
| KR20140015500A (ko) | 2014-02-06 |
| JP2014515821A (ja) | 2014-07-03 |
| US20140295459A1 (en) | 2014-10-02 |
| SG193630A1 (en) | 2013-10-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2012235767B2 (en) | Markers for identifying tumor cells, methods and kit thereof | |
| Zhu et al. | PROX1 promotes breast cancer invasion and metastasis through WNT/β-catenin pathway via interacting with hnRNPK | |
| Park et al. | Antibody-based detection of ERG rearrangement-positive prostate cancer | |
| Rishi et al. | Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437 | |
| Cheng et al. | Wnt5a suppresses colon cancer by inhibiting cell proliferation and epithelial–mesenchymal transition | |
| US8470542B2 (en) | Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95 | |
| Lu et al. | Increased expression of δ-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer | |
| Qiu et al. | Overexpression of CCT8 and its significance for tumor cell proliferation, migration and invasion in glioma | |
| Cuevas et al. | FGF-2 disrupts mitotic stability in prostate cancer through the intracellular trafficking protein CEP57 | |
| Lian et al. | THAP11, a novel binding protein of PCBP1, negatively regulates CD44 alternative splicing and cell invasion in a human hepatoma cell line | |
| Wang et al. | Sitagliptin affects gastric cancer cells proliferation by suppressing Melanoma‐associated antigen‐A3 expression through Yes‐associated protein inactivation | |
| Nie et al. | TXNIP interaction with the Her-1/2 pathway contributes to overall survival in breast cancer | |
| Mao et al. | CUL4B promotes bladder cancer metastasis and induces epithelial-to-mesenchymal transition by activating the Wnt/β-catenin signaling pathway | |
| Qiu et al. | RNF185 modulates JWA ubiquitination and promotes gastric cancer metastasis | |
| Shao et al. | High-level SAE2 promotes malignant phenotype and predicts outcome in gastric cancer | |
| CN110302382A (zh) | 一种靶向肿瘤细胞的药物 | |
| Heckler et al. | Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer | |
| Wang et al. | Upregulation of ALDH1B1 promotes tumor progression in osteosarcoma | |
| Lu et al. | Elevation of EIF4G1 promotes non‐small cell lung cancer progression by activating mTOR signalling | |
| Wang et al. | Evaluation of thymosin β4 in the regulation of epithelial-mesenchymal transformation in urothelial carcinoma | |
| Deng et al. | GID2 interacts with CDKN3 and regulates pancreatic cancer growth and apoptosis | |
| Hwang et al. | Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma | |
| Han et al. | Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology | |
| Zhao et al. | The role of Alix in the proliferation of human glioma cells | |
| Xu et al. | Retracted: Suppression of BMX‐ARHGAP fusion gene inhibits epithelial‐mesenchymal transition in gastric cancer cells via RhoA‐mediated blockade of JAK/STAT axis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |