AU2012214672B2 - Lipoprotein complexes and manufacturing and uses thereof - Google Patents

Lipoprotein complexes and manufacturing and uses thereof Download PDF

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Publication number
AU2012214672B2
AU2012214672B2 AU2012214672A AU2012214672A AU2012214672B2 AU 2012214672 B2 AU2012214672 B2 AU 2012214672B2 AU 2012214672 A AU2012214672 A AU 2012214672A AU 2012214672 A AU2012214672 A AU 2012214672A AU 2012214672 B2 AU2012214672 B2 AU 2012214672B2
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AU
Australia
Prior art keywords
apoa
lipid
population
lipoprotein
complexes
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AU2012214672A
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English (en)
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AU2012214672A1 (en
Inventor
Rose ACKERMANN
Jean-Louis Dasseux
Daniela Carmen Oniciu
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Abionyx Pharma SA
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Cerenis Therapeutics Holding SA
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Application filed by Cerenis Therapeutics Holding SA filed Critical Cerenis Therapeutics Holding SA
Publication of AU2012214672A1 publication Critical patent/AU2012214672A1/en
Application granted granted Critical
Publication of AU2012214672B2 publication Critical patent/AU2012214672B2/en
Priority to AU2015271986A priority Critical patent/AU2015271986B2/en
Priority to AU2018203258A priority patent/AU2018203258B9/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2012214672A 2011-02-07 2012-02-06 Lipoprotein complexes and manufacturing and uses thereof Active AU2012214672B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2015271986A AU2015271986B2 (en) 2011-02-07 2015-12-21 Lipoprotein complexes and manufacturing and uses thereof
AU2018203258A AU2018203258B9 (en) 2011-02-07 2018-05-10 Lipoprotein complexes and manufacturing and uses thereof

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161440371P 2011-02-07 2011-02-07
US61/440,371 2011-02-07
US201161452630P 2011-03-14 2011-03-14
US61/452,630 2011-03-14
US201161487263P 2011-05-17 2011-05-17
US61/487,263 2011-05-17
PCT/US2012/024020 WO2012109162A1 (en) 2011-02-07 2012-02-06 Lipoprotein complexes and manufacturing and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2015271986A Division AU2015271986B2 (en) 2011-02-07 2015-12-21 Lipoprotein complexes and manufacturing and uses thereof

Publications (2)

Publication Number Publication Date
AU2012214672A1 AU2012214672A1 (en) 2013-05-02
AU2012214672B2 true AU2012214672B2 (en) 2015-10-01

Family

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Application Number Title Priority Date Filing Date
AU2012214672A Active AU2012214672B2 (en) 2011-02-07 2012-02-06 Lipoprotein complexes and manufacturing and uses thereof
AU2015271986A Active AU2015271986B2 (en) 2011-02-07 2015-12-21 Lipoprotein complexes and manufacturing and uses thereof
AU2018203258A Active AU2018203258B9 (en) 2011-02-07 2018-05-10 Lipoprotein complexes and manufacturing and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2015271986A Active AU2015271986B2 (en) 2011-02-07 2015-12-21 Lipoprotein complexes and manufacturing and uses thereof
AU2018203258A Active AU2018203258B9 (en) 2011-02-07 2018-05-10 Lipoprotein complexes and manufacturing and uses thereof

Country Status (27)

Country Link
US (9) US20120232005A1 (https=)
EP (4) EP2673296B1 (https=)
JP (5) JP6219170B2 (https=)
KR (1) KR20140053848A (https=)
CN (4) CN105294859A (https=)
AU (3) AU2012214672B2 (https=)
CA (1) CA2826158A1 (https=)
CY (2) CY1121317T1 (https=)
DK (3) DK2673296T3 (https=)
ES (3) ES2994009T3 (https=)
HR (2) HRP20190138T1 (https=)
HU (2) HUE042314T2 (https=)
IL (1) IL227634B (https=)
IN (1) IN2013DN07828A (https=)
LT (2) LT2673296T (https=)
MX (2) MX343907B (https=)
PH (2) PH12013501644A1 (https=)
PL (2) PL2673296T3 (https=)
PT (2) PT2767546T (https=)
RS (2) RS58275B1 (https=)
RU (2) RU2017126088A (https=)
SG (2) SG10201801372YA (https=)
SI (2) SI2673296T1 (https=)
SM (2) SMT201900045T1 (https=)
TW (2) TW201737935A (https=)
WO (1) WO2012109162A1 (https=)
ZA (1) ZA201305628B (https=)

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