AU2012206621B2 - Use of liquid medium exchange by cross flow filtration in the preparation of drug suspensions - Google Patents

Use of liquid medium exchange by cross flow filtration in the preparation of drug suspensions Download PDF

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Publication number
AU2012206621B2
AU2012206621B2 AU2012206621A AU2012206621A AU2012206621B2 AU 2012206621 B2 AU2012206621 B2 AU 2012206621B2 AU 2012206621 A AU2012206621 A AU 2012206621A AU 2012206621 A AU2012206621 A AU 2012206621A AU 2012206621 B2 AU2012206621 B2 AU 2012206621B2
Authority
AU
Australia
Prior art keywords
liquid medium
drug
suspension
particles
diafiltration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2012206621A
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English (en)
Other versions
AU2012206621A1 (en
Inventor
Heiko Bothe
Hans Peter Niedermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Intervet International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet International BV filed Critical Intervet International BV
Publication of AU2012206621A1 publication Critical patent/AU2012206621A1/en
Application granted granted Critical
Publication of AU2012206621B2 publication Critical patent/AU2012206621B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
AU2012206621A 2011-01-12 2012-01-11 Use of liquid medium exchange by cross flow filtration in the preparation of drug suspensions Active AU2012206621B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161431942P 2011-01-12 2011-01-12
US61/431,942 2011-01-12
PCT/EP2012/050336 WO2012095439A1 (en) 2011-01-12 2012-01-11 Use of liquid medium exchange by cross flow filtration in the preparation of drug suspensions

Publications (2)

Publication Number Publication Date
AU2012206621A1 AU2012206621A1 (en) 2013-07-04
AU2012206621B2 true AU2012206621B2 (en) 2017-04-27

Family

ID=45478323

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012206621A Active AU2012206621B2 (en) 2011-01-12 2012-01-11 Use of liquid medium exchange by cross flow filtration in the preparation of drug suspensions

Country Status (10)

Country Link
US (1) US9066864B2 (enExample)
EP (1) EP2663287A1 (enExample)
JP (1) JP5934719B2 (enExample)
CN (1) CN103347499B (enExample)
AU (1) AU2012206621B2 (enExample)
BR (1) BR112013016851B1 (enExample)
CA (1) CA2823972C (enExample)
MX (1) MX346749B (enExample)
SG (2) SG10201807631SA (enExample)
WO (1) WO2012095439A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6478959B2 (ja) * 2016-09-07 2019-03-06 株式会社富士薬品 粒子含有組成物を製造するためのシステム及び方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037265A1 (en) * 2002-10-25 2004-05-06 Akzo Nobel N.V. Prolonged release pharmaceutical composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6340580B1 (en) 1999-05-12 2002-01-22 Metabolix, Inc. Methods for purifying polyhydroxy alkanoates
WO2001021290A1 (en) * 1999-09-17 2001-03-29 Danish Separation Systems As A method and an apparatus for continuous cross-flow diafiltration
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
WO2003055469A1 (en) * 2001-12-21 2003-07-10 Celator Technologies Inc. Improved polymer-lipid delivery vehicles
WO2003063877A1 (en) 2002-02-01 2003-08-07 Akzo Nobel N.V. Cefquinome composition for intra-mammary administration in cattle
ITMI20022674A1 (it) 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
WO2011072218A2 (en) * 2009-12-11 2011-06-16 Bind Biosciences Stable formulations for lyophilizing therapeutic particles

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037265A1 (en) * 2002-10-25 2004-05-06 Akzo Nobel N.V. Prolonged release pharmaceutical composition

Also Published As

Publication number Publication date
BR112013016851B1 (pt) 2021-08-31
US20130281425A1 (en) 2013-10-24
WO2012095439A1 (en) 2012-07-19
SG10201807631SA (en) 2018-10-30
US9066864B2 (en) 2015-06-30
EP2663287A1 (en) 2013-11-20
CN103347499A (zh) 2013-10-09
BR112013016851A2 (pt) 2016-10-04
CN103347499B (zh) 2017-04-05
CA2823972C (en) 2019-05-28
CA2823972A1 (en) 2012-07-19
JP5934719B2 (ja) 2016-06-15
JP2014502624A (ja) 2014-02-03
SG191963A1 (en) 2013-08-30
MX346749B (es) 2017-03-29
MX2013008118A (es) 2013-08-12
AU2012206621A1 (en) 2013-07-04

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