AU2010336403B2 - Radiopharmaceutical complexes - Google Patents

Radiopharmaceutical complexes Download PDF

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Publication number
AU2010336403B2
AU2010336403B2 AU2010336403A AU2010336403A AU2010336403B2 AU 2010336403 B2 AU2010336403 B2 AU 2010336403B2 AU 2010336403 A AU2010336403 A AU 2010336403A AU 2010336403 A AU2010336403 A AU 2010336403A AU 2010336403 B2 AU2010336403 B2 AU 2010336403B2
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AU
Australia
Prior art keywords
substituted
unsubstituted
complex
alkyl
linker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU2010336403A
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English (en)
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AU2010336403A1 (en
Inventor
Nathaniel G. Butlin
Darren Magda
Jide Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lumiphore Inc
Original Assignee
Lumiphore Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of AU2010336403A1 publication Critical patent/AU2010336403A1/en
Application granted granted Critical
Publication of AU2010336403B2 publication Critical patent/AU2010336403B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nuclear Medicine (AREA)
  • Pyridine Compounds (AREA)
AU2010336403A 2009-12-24 2010-12-23 Radiopharmaceutical complexes Ceased AU2010336403B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29015509P 2009-12-24 2009-12-24
US61/290,155 2009-12-24
PCT/US2010/062048 WO2011079291A1 (en) 2009-12-24 2010-12-23 Radiopharmaceutical complexes

Publications (2)

Publication Number Publication Date
AU2010336403A1 AU2010336403A1 (en) 2012-06-28
AU2010336403B2 true AU2010336403B2 (en) 2016-04-21

Family

ID=44196160

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010336403A Ceased AU2010336403B2 (en) 2009-12-24 2010-12-23 Radiopharmaceutical complexes

Country Status (5)

Country Link
US (2) US20110189088A1 (enExample)
EP (2) EP3263562A1 (enExample)
JP (4) JP2013515744A (enExample)
AU (1) AU2010336403B2 (enExample)
WO (1) WO2011079291A1 (enExample)

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EP2511266B1 (en) 2006-07-10 2019-09-04 The Regents of The University of California Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides
WO2011025790A1 (en) 2009-08-24 2011-03-03 Lumiphore, Inc. Macrocyclic hopo chelators
GB201002508D0 (en) * 2010-02-12 2010-03-31 Algeta As Product
GB201208309D0 (en) * 2012-05-11 2012-06-27 Algeta As Complexes
EP2920157B1 (en) * 2012-11-16 2019-09-11 Lumiphore, Inc. Di-macrocycles
US11453652B2 (en) 2013-03-15 2022-09-27 Lumiphore, Inc. Di-macrocycles
AU2015244201B2 (en) * 2014-04-09 2019-09-12 Lumiphore, Inc Macrocycles
CA2972080A1 (en) 2014-12-22 2016-06-30 Lumiphore, Inc. Functionalized linear ligands and complexes thereof
CR20180581A (es) * 2016-06-10 2019-02-11 Bayer Pharma AG Complejos radio-farmacéuticos
US11235076B2 (en) 2016-08-29 2022-02-01 Fred Hutchinson Cancer Research Center Chelating platform for delivery of radionuclides
WO2018130988A1 (en) * 2017-01-12 2018-07-19 Nestec S.A. Cryptate derivatives and their use as luminescent lanthanide complexes
WO2019246311A1 (en) * 2018-06-19 2019-12-26 Lumiphore, Inc. Macrocycle conjugates
WO2020086629A1 (en) * 2018-10-22 2020-04-30 The General Hospital Corporation Complexes and ligands
JP2024060110A (ja) * 2021-02-19 2024-05-02 住友化学株式会社 放射性金属錯体及びその製造方法
JP2024045789A (ja) * 2021-02-19 2024-04-03 住友化学株式会社 化合物及び金属錯体
KR20230173150A (ko) 2021-04-20 2023-12-26 테라파워, 엘엘씨 Ac-225 생성용 티타니아 기반 발생기
CN117180277A (zh) * 2023-08-04 2023-12-08 中国辐射防护研究院 一种核素标记的靶向探针及其制备方法和应用

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WO2000048990A1 (en) * 1999-02-18 2000-08-24 The Regents Of The University Of California Phthalamide-lanthanide complexes for use as luminescent markers
WO2008092120A1 (en) * 2007-01-25 2008-07-31 Lumiphore, Inc. Multi-color time resolved fluorophores based on macrocyclic lanthanide complexes

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939254A (en) * 1988-04-26 1990-07-03 The Regents Of The University Of California Template synthesis of macrocyclic catecholamide complexes
US5624901A (en) * 1994-04-15 1997-04-29 The Regents Of The University Of California 3-hydroxy-2(1H)-pyridinone chelating agents
WO2000048990A1 (en) * 1999-02-18 2000-08-24 The Regents Of The University Of California Phthalamide-lanthanide complexes for use as luminescent markers
WO2008092120A1 (en) * 2007-01-25 2008-07-31 Lumiphore, Inc. Multi-color time resolved fluorophores based on macrocyclic lanthanide complexes

Non-Patent Citations (1)

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Title
Journal of the American Chemical Society, 2003, vol. 125, no. 44, pp. 13324-13325 *

Also Published As

Publication number Publication date
JP2019052164A (ja) 2019-04-04
EP2516407A1 (en) 2012-10-31
WO2011079291A1 (en) 2011-06-30
JP2021006542A (ja) 2021-01-21
EP2516407A4 (en) 2013-06-12
JP2017119705A (ja) 2017-07-06
US20200024234A1 (en) 2020-01-23
US20110189088A1 (en) 2011-08-04
JP2013515744A (ja) 2013-05-09
EP3263562A1 (en) 2018-01-03
AU2010336403A1 (en) 2012-06-28

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired