AU2010317563B2 - Hydrophobic interaction chromatography membranes, and methods of use thereof - Google Patents

Hydrophobic interaction chromatography membranes, and methods of use thereof Download PDF

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Publication number
AU2010317563B2
AU2010317563B2 AU2010317563A AU2010317563A AU2010317563B2 AU 2010317563 B2 AU2010317563 B2 AU 2010317563B2 AU 2010317563 A AU2010317563 A AU 2010317563A AU 2010317563 A AU2010317563 A AU 2010317563A AU 2010317563 B2 AU2010317563 B2 AU 2010317563B2
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Australia
Prior art keywords
methacrylate
acrylate
composite material
support member
monomer
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AU2010317563A1 (en
Inventor
Elena N. Komkova
Alicja M. Mika
Marianne Pankratz
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Merck Millipore Ltd
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Merck Millipore Ltd
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246—Intercrosslinking of at least two polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04—Coating
    • C08J7/06—Coating with compositions not containing macromolecular substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/34—Chemical features in the manufacture of articles consisting of a foamed macromolecular core and a macromolecular surface layer having a higher density than the core
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/35—Composite foams, i.e. continuous macromolecular foams containing discontinuous cellular particles or fragments
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2205/00—Foams characterised by their properties
    • C08J2205/02—Foams characterised by their properties the finished foam itself being a gel or a gel being temporarily formed when processing the foamable composition
    • C08J2205/024—Organogel, i.e. a gel containing an organic composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
    • Y10T428/249978—Voids specified as micro
    • Y10T428/249979—Specified thickness of void-containing component [absolute or relative] or numerical cell dimension
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
    • Y10T428/249981—Plural void-containing components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2139—Coating or impregnation specified as porous or permeable to a specific substance [e.g., water vapor, air, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
AU2010317563A 2009-11-13 2010-11-12 Hydrophobic interaction chromatography membranes, and methods of use thereof Active AU2010317563B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26100909P 2009-11-13 2009-11-13
US61/261,009 2009-11-13
PCT/IB2010/003049 WO2011058439A1 (en) 2009-11-13 2010-11-12 Hydrophobic interaction chromatography membranes, and methods of use thereof

Publications (2)

Publication Number Publication Date
AU2010317563A1 AU2010317563A1 (en) 2012-06-21
AU2010317563B2 true AU2010317563B2 (en) 2014-06-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010317563A Active AU2010317563B2 (en) 2009-11-13 2010-11-12 Hydrophobic interaction chromatography membranes, and methods of use thereof

Country Status (9)

Country Link
US (1) US20110117626A1 (enExample)
EP (1) EP2499192B1 (enExample)
JP (1) JP2013510918A (enExample)
KR (3) KR20180099943A (enExample)
AU (1) AU2010317563B2 (enExample)
CA (1) CA2780095C (enExample)
ES (1) ES2820454T3 (enExample)
IN (1) IN2012DN05130A (enExample)
WO (1) WO2011058439A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104245078B (zh) 2012-04-25 2016-07-06 通用电气健康护理生物科学股份公司 分离方法和分离基质
BR112015005937A2 (pt) 2012-09-17 2017-07-04 Grace W R & Co meios e dispositivos cromatográficos
EP4089101A1 (en) * 2013-02-26 2022-11-16 Merck Millipore Ltd Mixed-mode chromatography membranes
ES2887110T3 (es) 2014-01-16 2021-12-21 Grace W R & Co Medios para cromatografía de afinidad y dispositivos para cromatografía
US11291215B2 (en) 2014-03-26 2022-04-05 Hydroxsys Holdings Limited Durable asymmetric composite membranes and modified substrates used in their preparation
US11389783B2 (en) 2014-05-02 2022-07-19 W.R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
US10335742B2 (en) * 2014-12-24 2019-07-02 Hydroxsys Holdings Limited Asymmetric composite membranes and modified substrates used in their preparation
PL3302784T3 (pl) 2015-06-05 2022-01-17 W.R. Grace & Co.-Conn. Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania
US10641751B2 (en) 2015-06-19 2020-05-05 Dionex Corporation Ion exchange chromatography column, method, and system thereof
US10379090B2 (en) * 2016-06-17 2019-08-13 Dionex Corporation Charge reversible ion exchange resins, chromatography column, method, and system thereof
EP3735307A1 (en) 2018-02-05 2020-11-11 Clemson University Research Foundation Channeled fibers in separation of biologically active nanoparticles
WO2020123714A1 (en) 2018-12-12 2020-06-18 Purilogics, LLC Affinity membrane and method of preparation
CN115015400B (zh) * 2022-01-28 2024-01-02 河南省人民医院 亲水有机聚合物毛细管电色谱整体柱及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5647979A (en) * 1996-06-14 1997-07-15 Bio-Rad Laboratories, Inc. One-step preparation of separation media for reversed-phase chromatography
US7316919B2 (en) * 2003-02-19 2008-01-08 Nysa Membrane Technologies Composite materials comprising supported porous gels
WO2010027955A2 (en) * 2008-09-02 2010-03-11 Natrix Separations Inc. Chromatography membranes, devices containing them, and methods of use thereof

Family Cites Families (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224415A (en) * 1958-07-18 1980-09-23 Rohm And Haas Company Polymerization processes and products therefrom
US3209915A (en) * 1962-03-06 1965-10-05 Aircraft Appliances And Equipm Filter
GB1149481A (en) * 1966-03-30 1969-04-23 Norris Filters Ltd Improvements in or relating to fluid filters
US3520803A (en) * 1968-12-24 1970-07-21 Ionics Membrane fluid separation apparatus and process
US3713921A (en) * 1971-04-01 1973-01-30 Gen Electric Geometry control of etched nuclear particle tracks
AU6069773A (en) * 1972-10-11 1975-03-27 Commw Scient Ind Res Org Compositions
US3939105A (en) * 1974-06-18 1976-02-17 Union Carbide Corporation Microporous polyurethane hydrogels, method and composites with natural and other synthetic fibers or films
FR2294731A1 (fr) * 1974-12-18 1976-07-16 Rhone Poulenc Ind Dispositif de contention pour appareil a membranes semi-permeables
US4108804A (en) * 1975-12-23 1978-08-22 Toru Seita Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel
JPS53107479A (en) * 1977-02-28 1978-09-19 Green Cross Corp:The Preparation of human lysozyme
JPS6030291B2 (ja) * 1978-03-20 1985-07-16 森永乳業株式会社 人顆粒球の分化増殖を促進するｈｇｉ糖蛋白質、ｈｇｉ糖蛋白質の製造法及びｈｇｉ糖蛋白質を含有する白血球減少症治療剤
US4170540A (en) * 1978-03-31 1979-10-09 Hooker Chemicals & Plastics Corp. Method for forming microporous membrane materials
US4230697A (en) * 1978-07-03 1980-10-28 Morinaga Milk Industry Co. Ltd. Virus-inactivated HGI-glycoprotein capable of stimulating proliferation and differentiation of human granulocyte, process for preparing same and leukopenia curative containing same
GB2070658B (en) * 1980-03-04 1984-02-29 Boer Mueboer Es Cipoipari Kuta Process for the production of chemically bonded non-woven sheet materials containing a binder of microheteroporous structure
US4473474A (en) * 1980-10-27 1984-09-25 Amf Inc. Charge modified microporous membrane, process for charge modifying said membrane and process for filtration of fluid
US4377481A (en) * 1980-11-14 1983-03-22 Abcor, Inc. Blended, polymeric, matrix membrane and process of making and using same
US4525527A (en) * 1982-01-25 1985-06-25 American Colloid Company Production process for highly water absorbable polymer
JPS6038112B2 (ja) * 1982-05-29 1985-08-30 キユーピー株式会社 卵白リゾチ−ムの溶出方法
JPS6019991B2 (ja) * 1982-06-02 1985-05-18 キユーピー株式会社 卵白リゾチ−ムの結晶化方法
US5034135A (en) * 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US4601828A (en) * 1983-02-07 1986-07-22 Yale University Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix
US4525374A (en) * 1984-02-27 1985-06-25 Manresa, Inc. Treating hydrophobic filters to render them hydrophilic
JPS61203131A (ja) * 1985-03-04 1986-09-09 Agency Of Ind Science & Technol キレート樹脂の製造方法
JPS62186940A (ja) * 1986-02-10 1987-08-15 Kanegafuchi Chem Ind Co Ltd リポ蛋白用吸着体
CA1283072C (en) * 1986-12-01 1991-04-16 Timothy Durance Process for the isolation and separation of lysozyme and avidin from eggwhite
US4888116A (en) * 1987-01-15 1989-12-19 The Dow Chemical Company Method of improving membrane properties via reaction of diazonium compounds or precursors
DE3872289T2 (de) * 1987-04-03 1993-02-11 Sumitomo Chemical Co Verfahren zur rueckgewinnung von gallium durch chelatharz.
US5059659A (en) * 1987-05-29 1991-10-22 Harry P. Gregor Surface treatments to impart hydrophilicity
JPH01503808A (ja) * 1987-07-16 1989-12-21 イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー（インコーポレイテツド） 固定化された凝集剤を用いるアフイニテイ分離
US5277915A (en) * 1987-10-30 1994-01-11 Fmc Corporation Gel-in-matrix containing a fractured hydrogel
US4889632A (en) * 1987-12-10 1989-12-26 Ceskoslovenska Akademie Ved Macroporous polymeric membranes for the separation of polymers and a method of their application
US5114585A (en) * 1988-03-01 1992-05-19 Gelman Sciences, Inc. Charged porous filter
US5019270A (en) * 1989-07-06 1991-05-28 Perseptive Biosystems, Inc. Perfusive chromatography
US5228989A (en) * 1989-07-06 1993-07-20 Perseptive Biosystems, Inc. Perfusive chromatography
US4944879A (en) * 1989-07-27 1990-07-31 Millipore Corporation Membrane having hydrophilic surface
US5147541A (en) * 1990-11-14 1992-09-15 Koch Membrane Systems, Inc. Spiral filtration module with strengthened membrane leaves and method of constructing same
US5130343A (en) * 1991-03-13 1992-07-14 Cornell Research Foundation, Inc. Process for producing uniform macroporous polymer beads
US5646001A (en) * 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
US5137633A (en) * 1991-06-26 1992-08-11 Millipore Corporation Hydrophobic membrane having hydrophilic and charged surface and process
DE69211010T2 (de) * 1991-10-21 1997-01-23 Cornell Res Foundation Inc Chromographiesäule mit makroporöser Polymerfüllung
US5176832A (en) * 1991-10-23 1993-01-05 The Dow Chemical Company Chromatographic separation of sugars using porous gel resins
SE9200827D0 (sv) * 1992-03-18 1992-03-18 Pharmacia Lkb Biotech Supet porous polysaccharide gels
US5470463A (en) * 1992-06-19 1995-11-28 Sepracor Inc. Passivated porous supports and methods for the preparation and use of same
US5906734A (en) * 1992-06-19 1999-05-25 Biosepra Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5445732A (en) * 1992-06-19 1995-08-29 Sepracor Inc. Passivated porous polymer supports and methods for the preparation and use of same
MX9303636A (es) * 1992-08-07 1994-07-29 Us Agriculture Composicion y metodo para repeler a las hormigas.
DE4234779A1 (de) * 1992-10-15 1994-04-21 Veba Oel Ag Trägerkatalysator und Verwendung desselben
US5316680A (en) * 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
DE69316231T2 (de) * 1992-10-21 1998-08-20 Cornell Res Foundation Inc Selektive, die porengrösse betreffende chemische modifikation poröser materialien
US5282971A (en) * 1993-05-11 1994-02-01 Pall Corporation Positively charged polyvinylidene fluoride membrane
SE503277C2 (sv) * 1993-07-20 1996-05-13 Alfa Laval Brewery Syst Ab Filter avsett för tvärströmsfiltrering
US5460720A (en) * 1993-08-12 1995-10-24 Schneider; Burnett M. Pleated membrane crossflow fluid separation device
US5403482A (en) * 1993-10-12 1995-04-04 Gelman Sciences Inc. Self-supporting, pleated, spirally wound filter and the corresponding process of making
DE4418156A1 (de) * 1994-05-25 1995-11-30 Basf Ag Verfahren zur Herstellung von stabilen Wasser-in-Öl-Emulsionen von hydrolysierten Polymerisaten von N-Vinylamiden und ihre Verwendung
US5728457A (en) * 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5972634A (en) * 1994-10-19 1999-10-26 The General Hospital Corporation Diagnostic assay for Alzheimer's disease: assessment of Aβ abnormalities
ATE198079T1 (de) * 1995-04-07 2000-12-15 Mogens Havsteen Jakobsen Verfahren zur photochemischen immobilisierung von liganden unter verwendung von chinonen
US5650496A (en) * 1995-04-14 1997-07-22 Cephalon, Inc. IGF-I purification process
US5756717A (en) * 1995-05-24 1998-05-26 Perseptive Biosystems, Inc Protein imaging
US5882521A (en) * 1996-04-18 1999-03-16 Waters Investment Ltd. Water-wettable chromatographic media for solid phase extraction
US6086769A (en) * 1996-09-16 2000-07-11 Commodore Separation Technologies, Inc. Supported liquid membrane separation
US6258276B1 (en) * 1996-10-18 2001-07-10 Mcmaster University Microporous membranes and uses thereof
US5929214A (en) * 1997-02-28 1999-07-27 Cornell Research Foundation, Inc. Thermally responsive polymer monoliths
US6271278B1 (en) * 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
DE19739218A1 (de) * 1997-09-08 1999-03-11 Boehringer Mannheim Gmbh Aufreinigung von Substanzen aus einer biologischen Probe
US6613234B2 (en) * 1998-04-06 2003-09-02 Ciphergen Biosystems, Inc. Large pore volume composite mineral oxide beads, their preparation and their applications for adsorption and chromatography
US6780582B1 (en) * 1998-07-14 2004-08-24 Zyomyx, Inc. Arrays of protein-capture agents and methods of use thereof
SE9803838D0 (sv) * 1998-11-09 1998-11-09 Knut Irgum A chromatography method and a column material useful in said method
US6277489B1 (en) * 1998-12-04 2001-08-21 The Regents Of The University Of California Support for high performance affinity chromatography and other uses
EP1057529A4 (en) * 1998-12-22 2004-08-25 Toray Industries MATERIALS FOR THE DISPOSAL OF BACTERIAL COMPONENTS
US6780327B1 (en) * 1999-02-25 2004-08-24 Pall Corporation Positively charged membrane
DE19943921C1 (de) * 1999-09-14 2001-01-11 Sartorius Gmbh Partikelgängige Vorrichtung zur Durchführung von Stofftrennungen mittels poröser flächiger Adsorptionsmembranen
US6461513B1 (en) * 2000-05-19 2002-10-08 Filtration Solutions, Inc. Secondary-flow enhanced filtration system
CA2428280A1 (en) * 2000-11-13 2002-05-16 Mcmaster University Gas separation device
EP1359994A4 (en) * 2000-12-22 2005-06-15 Osmonics Inc FILTRATION CARTRIDGES WITH BACK-CURRENT
US6989452B2 (en) * 2001-05-31 2006-01-24 Medarex, Inc. Disulfide prodrugs and linkers and stabilizers useful therefor
EP1397686B1 (en) * 2001-06-07 2006-10-18 Electrophoretics Limited Method for characterizing polypeptides
US6766817B2 (en) * 2001-07-25 2004-07-27 Tubarc Technologies, Llc Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action
US6887384B1 (en) * 2001-09-21 2005-05-03 The Regents Of The University Of California Monolithic microfluidic concentrators and mixers
KR100952265B1 (ko) * 2001-11-26 2010-04-09 인비스타 테크놀러지스 에스.에이.알.엘. 지지된 비스(인) 리간드 및 촉매 작용에 있어서의 그의용도
US6986847B2 (en) * 2002-05-10 2006-01-17 New Jersey Institute Of Technology Method and apparatus for isolation and purification of biomolecules
US6926823B2 (en) * 2002-06-03 2005-08-09 Varian, Inc. Polymer with superior polar retention for sample pretreatment
US7285255B2 (en) * 2002-12-10 2007-10-23 Ecolab Inc. Deodorizing and sanitizing employing a wicking device
EP1773485B1 (en) * 2004-06-07 2015-09-16 Natrix Separations Inc. Stable composite material comprising supported porous gels
CN100548455C (zh) * 2004-09-30 2009-10-14 麦克马斯特大学 包括层状亲水性涂层的复合材料
US7578939B2 (en) * 2004-12-09 2009-08-25 Board Of Trustees Of Michigan State University Ceramic membrane water filtration
US7311825B2 (en) * 2005-05-02 2007-12-25 Varian, Inc. Polymer modified porous substrate for solid phase extraction
CN101220528B (zh) * 2007-09-26 2010-10-06 天津工业大学 一种吸油纤维的制造方法
CN101903296B (zh) * 2008-02-12 2013-08-14 3M创新有限公司 复合聚合物过滤介质
WO2010117598A2 (en) * 2009-03-31 2010-10-14 3M Innovative Properties Company Hydrophobic monomers, hydrophobically-derivatized supports, and methods of making and using the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5647979A (en) * 1996-06-14 1997-07-15 Bio-Rad Laboratories, Inc. One-step preparation of separation media for reversed-phase chromatography
US7316919B2 (en) * 2003-02-19 2008-01-08 Nysa Membrane Technologies Composite materials comprising supported porous gels
WO2010027955A2 (en) * 2008-09-02 2010-03-11 Natrix Separations Inc. Chromatography membranes, devices containing them, and methods of use thereof

Also Published As

Publication number Publication date
KR20170104656A (ko) 2017-09-15
EP2499192A4 (en) 2014-08-06
AU2010317563A1 (en) 2012-06-21
KR20180099943A (ko) 2018-09-05
WO2011058439A1 (en) 2011-05-19
ES2820454T3 (es) 2021-04-21
IN2012DN05130A (enExample) 2015-10-23
US20110117626A1 (en) 2011-05-19
EP2499192A1 (en) 2012-09-19
EP2499192B1 (en) 2020-07-15
CA2780095A1 (en) 2011-05-19
JP2013510918A (ja) 2013-03-28
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