AU2010306671B2 - Compositions and methods for the treatment of drug-induced hand-foot syndrome - Google Patents

Compositions and methods for the treatment of drug-induced hand-foot syndrome Download PDF

Info

Publication number
AU2010306671B2
AU2010306671B2 AU2010306671A AU2010306671A AU2010306671B2 AU 2010306671 B2 AU2010306671 B2 AU 2010306671B2 AU 2010306671 A AU2010306671 A AU 2010306671A AU 2010306671 A AU2010306671 A AU 2010306671A AU 2010306671 B2 AU2010306671 B2 AU 2010306671B2
Authority
AU
Australia
Prior art keywords
drug
ppe
subject
phosphodiesterase inhibitor
symptoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2010306671A
Other languages
English (en)
Other versions
AU2010306671A1 (en
Inventor
Herbert Hurwitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of AU2010306671A1 publication Critical patent/AU2010306671A1/en
Application granted granted Critical
Publication of AU2010306671B2 publication Critical patent/AU2010306671B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2010306671A 2009-10-16 2010-10-15 Compositions and methods for the treatment of drug-induced hand-foot syndrome Active AU2010306671B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27909109P 2009-10-16 2009-10-16
US61/279,091 2009-10-16
PCT/US2010/052836 WO2011047256A1 (en) 2009-10-16 2010-10-15 Compositions and methods for the treatment of drug-induced hand-foot syndrome

Publications (2)

Publication Number Publication Date
AU2010306671A1 AU2010306671A1 (en) 2012-05-10
AU2010306671B2 true AU2010306671B2 (en) 2015-12-17

Family

ID=43876575

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010306671A Active AU2010306671B2 (en) 2009-10-16 2010-10-15 Compositions and methods for the treatment of drug-induced hand-foot syndrome

Country Status (6)

Country Link
US (2) US9220713B2 (cg-RX-API-DMAC7.html)
EP (1) EP2488642B1 (cg-RX-API-DMAC7.html)
JP (2) JP2013508295A (cg-RX-API-DMAC7.html)
CN (1) CN102648279B (cg-RX-API-DMAC7.html)
AU (1) AU2010306671B2 (cg-RX-API-DMAC7.html)
WO (1) WO2011047256A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102648279B (zh) * 2009-10-16 2015-11-25 杜克大学 用于治疗药物诱发的手足综合征的组合物与方法
WO2012125379A1 (en) * 2011-03-14 2012-09-20 Cellworks Research India Private Limited Compositions, process of preparation of said compositions and method of treating inflammatory diseases
EP3030239A4 (en) * 2013-06-11 2017-03-08 Kala Pharmaceuticals, Inc. Urea derivatives and uses thereof
WO2016144230A1 (en) * 2015-03-06 2016-09-15 Telefonaktiebolaget Lm Ericsson (Publ) Method, network device, computer program and computer program product for mobile service chaining
CN110892065A (zh) * 2017-08-18 2020-03-17 宝洁公司 清洁方法
CA3085013A1 (en) 2017-12-13 2019-06-20 Onquality Pharmaceuticals China Ltd. A method for preventing or treating egfr-inhibition associated diseases
TW201943428A (zh) 2018-04-16 2019-11-16 大陸商上海岸闊醫藥科技有限公司 預防或治療腫瘤療法副作用的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9019A (en) * 1852-06-15 Charles fleischbl
US2002A (en) * 1841-03-12 Tor and planter for plowing
US9004A (en) * 1852-06-08 Improvement in seed-planters
US20020028237A1 (en) * 2000-04-20 2002-03-07 Colbern Gail T. Method for reducing toxicity of a cytotoxic agent
US6683080B2 (en) * 2001-02-02 2004-01-27 Pfizer Inc. Treatment of diabetes mellitus
US20090048179A1 (en) 2005-02-22 2009-02-19 Cedars-Sinai Medical Center Use of 5-phosphodiesterase inhibitors to enhance the permeability of the blood-brain barrier of abnormal brain tissue and the blood-tumor barrier
EP1850852A4 (en) 2005-02-22 2009-11-18 Cedars Sinai Medical Center USE OF SILDENAFIL, VARDENAFIL AND OTHER 5-PHOSPHODIESTERASE INHIBITORS TO INCREASE THE PERMEABILITY OF THE ABNORMAL BLOOD-BRAIN DISEASE
RU2008122978A (ru) * 2005-11-09 2009-12-20 Комбинаторкс, Инкорпорейтед (Us) Способы, композиции и наборы для лечения медицинских состояний
US20090197922A1 (en) * 2006-01-24 2009-08-06 The University Of Chicago Compositions and methods for treating pulmonary hypertension
PT2035006E (pt) 2006-06-01 2010-04-22 Nobera Pharma Sl Utilização de alopurinol para o tratamento da eritrodisestesia palmo-plantar
EP2246057A1 (en) 2009-04-29 2010-11-03 Nobera Pharma, S.L. Use of allopurinol for the treatment of hand foot skin reaction
CN102648279B (zh) * 2009-10-16 2015-11-25 杜克大学 用于治疗药物诱发的手足综合征的组合物与方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PUSZTAI, L., et al., Journal of Clinical Oncology, 2003, vol. 21, pages 3454-3461 *

Also Published As

Publication number Publication date
EP2488642A4 (en) 2013-03-06
EP2488642A1 (en) 2012-08-22
JP2013508295A (ja) 2013-03-07
US9220713B2 (en) 2015-12-29
WO2011047256A1 (en) 2011-04-21
US9629845B2 (en) 2017-04-25
CN102648279B (zh) 2015-11-25
CN102648279A (zh) 2012-08-22
US20160074405A1 (en) 2016-03-17
AU2010306671A1 (en) 2012-05-10
US20120258970A1 (en) 2012-10-11
JP6063550B2 (ja) 2017-01-18
JP2016094450A (ja) 2016-05-26
EP2488642B1 (en) 2015-03-11

Similar Documents

Publication Publication Date Title
US9629845B2 (en) Compositions and methods for the treatment of drug-induced hand-foot syndrome
RU2662298C2 (ru) Лечение рака комбинацией плинабулина и таксана
Frohman et al. Part II. High-dose methotrexate with leucovorin rescue for severe COVID-19: an immune stabilization strategy for SARS-CoV-2 induced ‘PANIC’attack
JP2017503801A (ja) 小児における急性呼吸促迫症候群の治療のための吸入一酸化窒素ガスを使用する方法
JP2020055884A (ja) がんのためのグルフォスファミド組み合わせ療法
CN108025007A (zh) 曲美他嗪在制备防治肝病的药物中的用途
US20170027977A1 (en) Methods useful in the prevention of hypoxic injury
WO2021023291A1 (zh) 原黄素在肺癌治疗中的应用
KR20200050761A (ko) 다이설피람을 포함하는 항암용 조성물
WO2023026247A1 (en) Combination of a nurr1 agonist with at least one of an aldosterone antagonist, an insulin modulator and a sulfonylurea
KR20240005881A (ko) 빈혈 치료를 위한 펠라브레시브의 용도
EP4181887A1 (en) Pde3 inhibitors for treating viral infections
CN110876803B (zh) 一种包含乳蛋白和油酸的药物组合物
Xu et al. Gastrodin alleviates angiotensin Ⅱ-induced hypertension and myocardial apoptosis and PRDX2/p53 pathway activation
KR20250079206A (ko) 간기능 장애의 치료를 위한 니타조사나이드
IT202300010005A1 (it) Rutina per il trattamento dell’epidermolisi bollosa
CN120919330A (zh) 预防和/或治疗哺乳动物心脏系统疾病的药物组合物
CN121285550A (zh) 一种吡咯并[2,3-c]吡啶酮化合物的联用药物组合物及其用途
EP4452275A1 (en) Combination of cisplatin and elimusertib for the treatment of pediatric liver cancers
CN119302935A (zh) 苄索氯胺作为stat3抑制剂在制备治疗头颈部肿瘤药物的应用
CN117244071A (zh) 一种Ph+ALL的联合用药组合物及其应用
KR20130020945A (ko) 골수이형성 증후군을 치료하기 위한 조성물 및 방법
JP2024531765A (ja) がん治療のための三剤療法
JP2008501785A (ja) 子宮腫瘍の治療用医薬の調製のための7−t−ブトキシイミノメチルカンプトテシンの使用
Okamoto et al. Successful Treatment with Tacrolimus in a Case of Lung-dominant Connective Tissue Disease

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)