AU2010306559B2 - Recombinant modified vaccinia Ankara (MVA) vaccinia virus containing restructured insertion sites - Google Patents

Recombinant modified vaccinia Ankara (MVA) vaccinia virus containing restructured insertion sites Download PDF

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AU2010306559B2
AU2010306559B2 AU2010306559A AU2010306559A AU2010306559B2 AU 2010306559 B2 AU2010306559 B2 AU 2010306559B2 AU 2010306559 A AU2010306559 A AU 2010306559A AU 2010306559 A AU2010306559 A AU 2010306559A AU 2010306559 B2 AU2010306559 B2 AU 2010306559B2
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nucleic acid
mva
virus
essential
recombinant
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AU2010306559A1 (en
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Patricia L. Earl
Bernard Moss
Linda S. Wyatt
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US Department of Health and Human Services
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24151Methods of production or purification of viral material
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    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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AU2010306559A 2009-10-16 2010-10-15 Recombinant modified vaccinia Ankara (MVA) vaccinia virus containing restructured insertion sites Active AU2010306559B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25232609P 2009-10-16 2009-10-16
US61/252,326 2009-10-16
PCT/US2010/052929 WO2011047324A1 (en) 2009-10-16 2010-10-15 Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites

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AU2010306559A1 AU2010306559A1 (en) 2012-06-07
AU2010306559B2 true AU2010306559B2 (en) 2015-07-16

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US (2) US9133480B2 (OSRAM)
EP (1) EP2488649B1 (OSRAM)
JP (1) JP5789263B2 (OSRAM)
AU (1) AU2010306559B2 (OSRAM)
CA (1) CA2777744C (OSRAM)
DK (1) DK2488649T3 (OSRAM)
WO (1) WO2011047324A1 (OSRAM)
ZA (1) ZA201203551B (OSRAM)

Families Citing this family (16)

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WO2008142479A2 (en) * 2006-08-25 2008-11-27 The Government Of The United States Of Amercia, As Represented By The Secretary, Department Of Health And Human Services Intergenic sites between conserved genes in the genome of modified vaccinia ankara (mva) vaccinia virus
US8580276B2 (en) 2009-06-05 2013-11-12 City Of Hope Genetically stable recombinant modified vaccinia ankara (rMVA) vaccines and methods of preparation thereof
EP2488649B1 (en) 2009-10-16 2019-04-03 The U.S.A. as represented by the Secretary, Department of Health and Human Services Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites
EP2620446A1 (en) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
US10894966B2 (en) 2014-09-26 2021-01-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Virus-based expression vectors and uses thereof
US11701418B2 (en) 2015-01-12 2023-07-18 Geovax, Inc. Replication-deficient modified vaccinia Ankara (MVA) expressing Ebola virus glycoprotein (GP) and matrix protein (VP40)
US20190038659A1 (en) 2015-09-29 2019-02-07 The Usa, As Represented By The Secretary, Department Of Health And Human Services Methods of treating and preventing amyotrophic lateral sclerosis
AU2017206102C1 (en) 2016-01-08 2022-02-10 Geovax Inc. Compositions and methods for generating an immune response to a tumor associated antigen
US20190030157A1 (en) 2016-02-03 2019-01-31 Geovax Inc. Compositions and Methods for Generating an Immune Response to a Flavivirus
US11052148B2 (en) * 2016-05-30 2021-07-06 Geo Vax, Inc. Compositions and methods for generating an immune response to hepatitis B virus
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
WO2019152746A2 (en) 2018-01-30 2019-08-08 Emory University Compositions and methods for promoting immune responses to human immunodeficiency virus
CN112512568A (zh) 2018-05-11 2021-03-16 希望之城 遗传修饰的重组痘苗安卡拉(rmva)疫苗改善的稳定性及其制备方法
WO2021066612A2 (ko) * 2019-10-02 2021-04-08 주식회사 바이오녹스 종양 표적화 단백질 또는 이의 단편 및 그것에 결합하는 항체 및 이의 용도
AU2020384323A1 (en) 2019-11-14 2022-06-02 Aelix Therapeutics, S.L. Dosage regimens for vaccines
AU2022215566A1 (en) 2021-02-02 2023-08-17 Geovax, Inc. Viral constructs for use in enhancing t-cell priming during vaccination

Citations (1)

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WO2008142479A2 (en) * 2006-08-25 2008-11-27 The Government Of The United States Of Amercia, As Represented By The Secretary, Department Of Health And Human Services Intergenic sites between conserved genes in the genome of modified vaccinia ankara (mva) vaccinia virus

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PL218318B1 (pl) 2002-05-16 2014-11-28 Bavarian Nordic As Rekombinowany wirus krowianki Ankara (MVA), zawierająca go komórka, szczepionka lub kompozycja farmaceutyczna, sposób lub zestaw do jego otrzymywania, sekwencja DNA zawierająca genom tego wirusa oraz sposób wykrywania tego wirusa lub komórek nim zainfekowanych
EP2359851A3 (en) 2003-03-28 2011-08-31 The Government of the United States of America, represented by The Secretary, Department of Health and Human Services MVA expressing modified hiv envelope, gag, and pol genes
EP2199400A1 (en) 2008-12-22 2010-06-23 Emergent Product Development Germany GmbH Single recombination system and methods of use
EP2488649B1 (en) 2009-10-16 2019-04-03 The U.S.A. as represented by the Secretary, Department of Health and Human Services Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2008142479A2 (en) * 2006-08-25 2008-11-27 The Government Of The United States Of Amercia, As Represented By The Secretary, Department Of Health And Human Services Intergenic sites between conserved genes in the genome of modified vaccinia ankara (mva) vaccinia virus

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TIMM, A. et al. Vaccine, 2006, Vol.24, p.4618-4621 *

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Publication number Publication date
AU2010306559A1 (en) 2012-06-07
ZA201203551B (en) 2013-01-30
US9879231B2 (en) 2018-01-30
WO2011047324A1 (en) 2011-04-21
DK2488649T3 (da) 2019-06-17
US20120263750A1 (en) 2012-10-18
JP2013507935A (ja) 2013-03-07
EP2488649B1 (en) 2019-04-03
CA2777744C (en) 2019-09-24
CA2777744A1 (en) 2011-04-21
EP2488649A1 (en) 2012-08-22
US20160040135A1 (en) 2016-02-11
US9133480B2 (en) 2015-09-15
JP5789263B2 (ja) 2015-10-07

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