AU2009296456B2 - Use of pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP analogs as adjunctive treatments with anticancer agents - Google Patents

Use of pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP analogs as adjunctive treatments with anticancer agents Download PDF

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Publication number
AU2009296456B2
AU2009296456B2 AU2009296456A AU2009296456A AU2009296456B2 AU 2009296456 B2 AU2009296456 B2 AU 2009296456B2 AU 2009296456 A AU2009296456 A AU 2009296456A AU 2009296456 A AU2009296456 A AU 2009296456A AU 2009296456 B2 AU2009296456 B2 AU 2009296456B2
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AU
Australia
Prior art keywords
pacap38
pacap
analog
subject
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009296456A
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English (en)
Other versions
AU2009296456A1 (en
Inventor
Vecihi Batuman
David H. Coy
Min Li
Jerome L. Maderdrut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
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Tulane University
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Publication date
Application filed by Tulane University filed Critical Tulane University
Publication of AU2009296456A1 publication Critical patent/AU2009296456A1/en
Application granted granted Critical
Publication of AU2009296456B2 publication Critical patent/AU2009296456B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AU2009296456A 2008-09-25 2009-09-25 Use of pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP analogs as adjunctive treatments with anticancer agents Ceased AU2009296456B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19416608P 2008-09-25 2008-09-25
US61/194,166 2008-09-25
PCT/US2009/058445 WO2010036936A2 (en) 2008-09-25 2009-09-25 Use of pituitary adenylate cyclase-activating polypeptide (pacap) and pacap analogs as adjunctive treatments with anticancer agents

Publications (2)

Publication Number Publication Date
AU2009296456A1 AU2009296456A1 (en) 2010-04-01
AU2009296456B2 true AU2009296456B2 (en) 2016-06-16

Family

ID=42060409

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009296456A Ceased AU2009296456B2 (en) 2008-09-25 2009-09-25 Use of pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP analogs as adjunctive treatments with anticancer agents

Country Status (7)

Country Link
US (1) US20110268789A1 (https=)
EP (1) EP2337577A4 (https=)
JP (1) JP2012503674A (https=)
CN (1) CN102215859B (https=)
AU (1) AU2009296456B2 (https=)
CA (1) CA2738549A1 (https=)
WO (1) WO2010036936A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2779496A1 (en) 2009-11-02 2011-05-05 The Administrators Of The Tulane Educational Fund Analogs of pitutary adenylate cyclase-activating polypeptide (pacap) and methods for their use
EP2533795A4 (en) * 2010-02-05 2013-10-16 Univ Tulane USE OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) AND PACAP ANALOGUE AS SUPPORTING TREATMENT WITH INHIBITORS OF CALCINEURIN OR INHIBITORS OF MTOR COMPLEXES
WO2013074966A1 (en) * 2011-11-17 2013-05-23 The Administrators Of The Tulane Educational Fund Use of pituitary adenylate cyclase activating polypeptide (pacap) and pacap analogs for treating contrast -indused nephropathy
CN103145851B (zh) * 2013-02-22 2014-07-02 暨南大学 重组蛋白PACAP38-NtA及其编码基因与应用
EP3565573B1 (en) 2017-01-05 2023-08-23 The Regents of The University of California Pac1 receptor agonists (maxcaps) and uses thereof
ES2677242B1 (es) * 2017-01-31 2019-03-27 Univ Alcala Henares Nanoconjugados formados por moléculas dendríticas y péptidos como agentes antitumorales frente al cáncer
EP3712164A4 (en) * 2017-11-14 2021-08-18 Senju Pharmaceutical Co., Ltd. PEPTIDE STABILIZED BY PACAP
US20220202905A1 (en) * 2019-05-14 2022-06-30 Senju Pharmaceutical Co., Ltd. Composition for preventing or treating neurotrophic keratitis which contains pacap peptide or stabilized pacap peptide
DE102024001175A1 (de) * 2024-04-04 2025-10-09 ReViSan Healthcare GmbH Zubereitung zur Behandlung von entzündlichen Erkrankungen der Atemwege.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040038888A1 (en) * 2002-05-03 2004-02-26 Alex Mercer Functional role and potential therapeutic use of PACAP, VIP and Maxadilan in relation to adult neural stem or progenitor cells
WO2006012394A1 (en) * 2004-07-21 2006-02-02 Tulane University Health Sciences Center Treatment of renal dysfunction and multiple myeloma using pacap compounds
US20080108573A1 (en) * 2004-06-11 2008-05-08 Duggan Karen A Compositions And Methods For Treatment Of Cardiovascular Disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2190533A2 (en) * 2007-09-11 2010-06-02 Mondobiotech Laboratories AG Use of a peptide as a therapeutic agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040038888A1 (en) * 2002-05-03 2004-02-26 Alex Mercer Functional role and potential therapeutic use of PACAP, VIP and Maxadilan in relation to adult neural stem or progenitor cells
US20080108573A1 (en) * 2004-06-11 2008-05-08 Duggan Karen A Compositions And Methods For Treatment Of Cardiovascular Disease
WO2006012394A1 (en) * 2004-07-21 2006-02-02 Tulane University Health Sciences Center Treatment of renal dysfunction and multiple myeloma using pacap compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Aubert, N et al (2008) Neurobiology of Disease 32: 66-80 *

Also Published As

Publication number Publication date
EP2337577A4 (en) 2012-08-15
AU2009296456A1 (en) 2010-04-01
US20110268789A1 (en) 2011-11-03
EP2337577A1 (en) 2011-06-29
WO2010036936A2 (en) 2010-04-01
CA2738549A1 (en) 2010-04-01
WO2010036936A9 (en) 2010-07-15
JP2012503674A (ja) 2012-02-09
CN102215859B (zh) 2016-04-20
CN102215859A (zh) 2011-10-12

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired