AU2009292970B2 - Genus-wide Chlamydial peptide vaccine antigens - Google Patents

Genus-wide Chlamydial peptide vaccine antigens Download PDF

Info

Publication number
AU2009292970B2
AU2009292970B2 AU2009292970A AU2009292970A AU2009292970B2 AU 2009292970 B2 AU2009292970 B2 AU 2009292970B2 AU 2009292970 A AU2009292970 A AU 2009292970A AU 2009292970 A AU2009292970 A AU 2009292970A AU 2009292970 B2 AU2009292970 B2 AU 2009292970B2
Authority
AU
Australia
Prior art keywords
seq
peptide
immunogenic
peptides
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009292970A
Other languages
English (en)
Other versions
AU2009292970A1 (en
Inventor
Alan P. Hudson
Judith Whittum-Hudson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wayne State University
Original Assignee
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wayne State University filed Critical Wayne State University
Publication of AU2009292970A1 publication Critical patent/AU2009292970A1/en
Application granted granted Critical
Publication of AU2009292970B2 publication Critical patent/AU2009292970B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/125—Gram-negative bacteria from Chlamydiales (O)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/118—Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56927—Chlamydia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU2009292970A 2008-09-21 2009-09-21 Genus-wide Chlamydial peptide vaccine antigens Ceased AU2009292970B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9876908P 2008-09-21 2008-09-21
US61/098,769 2008-09-21
PCT/US2009/057700 WO2010033923A2 (en) 2008-09-21 2009-09-21 Genus-wide chlamydial peptide vaccine antigens

Publications (2)

Publication Number Publication Date
AU2009292970A1 AU2009292970A1 (en) 2010-03-25
AU2009292970B2 true AU2009292970B2 (en) 2015-05-07

Family

ID=42040185

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009292970A Ceased AU2009292970B2 (en) 2008-09-21 2009-09-21 Genus-wide Chlamydial peptide vaccine antigens

Country Status (6)

Country Link
US (1) US8637040B2 (https=)
EP (1) EP2337789A4 (https=)
JP (1) JP5798034B2 (https=)
AU (1) AU2009292970B2 (https=)
CA (1) CA2774336A1 (https=)
WO (1) WO2010033923A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011153532A1 (en) * 2010-06-04 2011-12-08 Flow Pharma Inc. Peptide particle formulation
US10293044B2 (en) 2014-04-18 2019-05-21 Auburn University Particulate formulations for improving feed conversion rate in a subject
CN106232106B (zh) * 2014-04-18 2020-08-11 奥本大学 用于诱导先天性和适应性免疫力的颗粒状疫苗制剂
US11834512B2 (en) 2020-05-04 2023-12-05 The Regents Of The University Of California Inhibiting anti-ENPP1 antibodies
EP4661878A2 (en) * 2023-02-07 2025-12-17 Merck Sharp & Dohme LLC Adjuvant formulations including low viscosity chitosan or chitosan derivatives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840297A (en) * 1993-03-19 1998-11-24 Johns Hopkins University Vaccine comprising anti-idiotypic antibody to chlamydia GLXA and process
WO2003037172A2 (en) * 2001-11-01 2003-05-08 Gpc Biotech Inc. Endothelial-cell binding peptides for diagnosis and therapy
US20070065387A1 (en) * 2005-09-16 2007-03-22 Beck William A Method for enhancing the effect of particulate benefit agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215780D0 (en) * 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
US5656271A (en) 1993-03-19 1997-08-12 The Johns Hopkins University Oral vaccine comprising anti-idiotypic antibody to chlamydia glycolipid exoantigen and process
CA2185568C (en) 1994-03-16 2001-07-03 Alex Bruce Macdonald Chlamydia vaccines and process
US5716713A (en) * 1994-12-16 1998-02-10 Ceramic Packaging, Inc. Stacked planar transformer
US20020001597A1 (en) * 2000-04-06 2002-01-03 Stuart Elizabeth S. Chlamydial glycolipid vaccines
JP2007532913A (ja) 2004-04-16 2007-11-15 ユニバーシティー オブ マサチューセッツ 細胞内病原体の検出法および定量化法
WO2007007325A2 (en) * 2005-07-07 2007-01-18 Fulcrum Sp Ltd. Sp1 polypeptides, modified sp1 polypeptides and uses thereof
US7928076B2 (en) * 2005-12-15 2011-04-19 E. I. Du Pont De Nemours And Company Polypropylene binding peptides and methods of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840297A (en) * 1993-03-19 1998-11-24 Johns Hopkins University Vaccine comprising anti-idiotypic antibody to chlamydia GLXA and process
WO2003037172A2 (en) * 2001-11-01 2003-05-08 Gpc Biotech Inc. Endothelial-cell binding peptides for diagnosis and therapy
US20070065387A1 (en) * 2005-09-16 2007-03-22 Beck William A Method for enhancing the effect of particulate benefit agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Clarkson T et al, Nature, 1991, 352:624-628 *

Also Published As

Publication number Publication date
US20110236484A1 (en) 2011-09-29
JP5798034B2 (ja) 2015-10-21
US8637040B2 (en) 2014-01-28
JP2012502663A (ja) 2012-02-02
EP2337789A2 (en) 2011-06-29
CA2774336A1 (en) 2010-03-25
WO2010033923A2 (en) 2010-03-25
WO2010033923A3 (en) 2010-07-22
AU2009292970A1 (en) 2010-03-25
EP2337789A4 (en) 2012-04-04

Similar Documents

Publication Publication Date Title
KR100644953B1 (ko) 다성분 백신
US7022483B1 (en) Methods for identifying and isolating antigen-specific T cells
US6787154B2 (en) Artificial antigen presenting cells
US9023348B2 (en) Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
JP2018086029A (ja) バイオフィルムの除去のための組成物および方法
JP3565351B2 (ja) 免疫応答を惹起するための、多数エピトープ含有抗原の再構成法および組成物
Whittum-Hudson et al. Oral immunization with an anti–idiotypic antibody to the exoglycolipid antigen protects against experimental Chlamydia trachomatis infection
JP2019163253A (ja) クラミジア種（Ｃｈｌａｍｙｄｉａ ｓｐ．）に対するワクチン
AU2009292970B2 (en) Genus-wide Chlamydial peptide vaccine antigens
Zafiropoulos et al. Induction of antigen-specific isotype switching by in vitro immunization of human naive B lymphocytes
WO2001080833A1 (en) Methods for isolation, quantification, characterization and modulation of antigen-specific t cells
JP2007526318A (ja) Ｃｈｌａｍｙｄｉａｐｎｅｕｍｏｎｉａｅに対する免疫原性組成物
CA2683888A1 (en) Chlamydial antigens as reagents for diagnosis and treatment of chlamydial infection and disease
WO1994021291A1 (en) Chlamydia vaccine and process
Reed et al. Multiple antigen constructs (MACs): induction of sterile immunity against sporozoite stage of rodent malaria parasites, Plasmodium berghei and Plasmodium yoelii
US5656271A (en) Oral vaccine comprising anti-idiotypic antibody to chlamydia glycolipid exoantigen and process
US20230257703A1 (en) Nanoscale polymeric micellar scaffolds for rapid and efficient antibody production
US20030007973A1 (en) Methods and compositions for manipulation of the immune response using anti-metallothionein antibody
CA2185568C (en) Chlamydia vaccines and process
WO2002004017A2 (en) Method for preparing oral vaccines
Tammiruusu CD8+ T Cell Response in Experimental Chlamydia pneumoniae Infection
CN1984678A (zh) 用于肺炎衣原体的免疫原性组合物
HK1141034A1 (en) Peptide mimics of conserved gonococcal epitopes and methods and compositions using them
HK1141034B (en) Peptide mimics of conserved gonococcal epitopes and methods and compositions using them
MXPA98009586A (en) Method and composition for the reconformation of multi-peptide antigens to start an animal response

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired