AU2008344922A1 - Chromane derivatives as TRPV3 modulators - Google Patents

Chromane derivatives as TRPV3 modulators Download PDF

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Publication number
AU2008344922A1
AU2008344922A1 AU2008344922A AU2008344922A AU2008344922A1 AU 2008344922 A1 AU2008344922 A1 AU 2008344922A1 AU 2008344922 A AU2008344922 A AU 2008344922A AU 2008344922 A AU2008344922 A AU 2008344922A AU 2008344922 A1 AU2008344922 A1 AU 2008344922A1
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AU
Australia
Prior art keywords
substituted
compound
unsubstituted
chromene
dihydrospiro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008344922A
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English (en)
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AU2008344922A2 (en
Inventor
Laxmikant Atmaram Gharat
Vidya Ganapati Kattige
Neelima Khairatkar Joshi
Prasadarao Lingam V S
Ajit Shankar Mindhe
Shantaram Kashinath Phatangare
Abraham Thomas
Deepak Vitthal Ukirde
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Ichnos Sciences SA
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Glenmark Pharmaceuticals SA
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Filing date
Publication date
Application filed by Glenmark Pharmaceuticals SA filed Critical Glenmark Pharmaceuticals SA
Publication of AU2008344922A1 publication Critical patent/AU2008344922A1/en
Publication of AU2008344922A2 publication Critical patent/AU2008344922A2/en
Abandoned legal-status Critical Current

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
AU2008344922A 2007-12-18 2008-12-16 Chromane derivatives as TRPV3 modulators Abandoned AU2008344922A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
IN2481MU2007 2007-12-18
IN2481/MUM/2007 2007-12-18
US1999508P 2008-01-09 2008-01-09
US61/019.995 2008-01-09
IN647/MUM/2008 2008-03-26
IN647MU2008 2008-03-26
US4393108P 2008-04-10 2008-04-10
US61/043.931 2008-04-10
PCT/IN2008/000838 WO2009084034A2 (en) 2007-12-18 2008-12-16 Chromane derivatives as trpv3 modulators

Publications (2)

Publication Number Publication Date
AU2008344922A1 true AU2008344922A1 (en) 2012-01-19
AU2008344922A2 AU2008344922A2 (en) 2012-04-26

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ID=40824849

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008344922A Abandoned AU2008344922A1 (en) 2007-12-18 2008-12-16 Chromane derivatives as TRPV3 modulators

Country Status (10)

Country Link
US (1) US8487121B2 (enExample)
EP (1) EP2254879A4 (enExample)
JP (1) JP2011519343A (enExample)
AU (1) AU2008344922A1 (enExample)
CA (1) CA2706566A1 (enExample)
EA (1) EA201000675A1 (enExample)
GE (1) GEP20125707B (enExample)
MX (1) MX2010005704A (enExample)
NZ (1) NZ595776A (enExample)
WO (1) WO2009084034A2 (enExample)

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EP2449112A1 (en) 2009-07-01 2012-05-09 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for severe combined immunodeficiency (scid)
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
HUE041294T2 (hu) 2011-12-16 2019-05-28 Poseida Therapeutics Inc TRPC4 modulátorok a fájdalom kezelésére vagy megelõzésére
MX2017005663A (es) * 2014-10-31 2018-03-01 Abbvie Sarl Tetrahidropiranos sustituidos y metodo de uso.
WO2018118670A1 (en) * 2016-12-20 2018-06-28 Merck Sharp & Dohme Corp. Antidiabetic spirochroman compounds
RU2713946C1 (ru) * 2019-11-13 2020-02-11 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) 4,7-диметил-3,4,4a,5,8,8a-гексагидроспиро[хромен-2,1'-циклогексан]-4,8-диол в качестве анальгезирующего средства
CN120882726A (zh) * 2022-12-26 2025-10-31 阳光安津(南京)生物医药科技有限公司 包括杂芳环的化合物及其组合物和方法

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Publication number Publication date
EP2254879A2 (en) 2010-12-01
WO2009084034A2 (en) 2009-07-09
AU2008344922A2 (en) 2012-04-26
CA2706566A1 (en) 2009-07-09
US20100311778A1 (en) 2010-12-09
JP2011519343A (ja) 2011-07-07
EA201000675A1 (ru) 2011-06-30
EP2254879A4 (en) 2012-10-31
MX2010005704A (es) 2010-08-17
NZ595776A (en) 2013-08-30
WO2009084034A3 (en) 2012-01-19
US8487121B2 (en) 2013-07-16
GEP20125707B (en) 2012-12-10

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