AU2008343919B2 - Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein - Google Patents

Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein Download PDF

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Publication number
AU2008343919B2
AU2008343919B2 AU2008343919A AU2008343919A AU2008343919B2 AU 2008343919 B2 AU2008343919 B2 AU 2008343919B2 AU 2008343919 A AU2008343919 A AU 2008343919A AU 2008343919 A AU2008343919 A AU 2008343919A AU 2008343919 B2 AU2008343919 B2 AU 2008343919B2
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AU
Australia
Prior art keywords
vsv
protein
cells
virus
cell
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Ceased
Application number
AU2008343919A
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English (en)
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AU2008343919A1 (en
Inventor
Roger M. Hendry
J. Erik Johnson
Christopher L. Parks
Maninder K. Sidhu
Susan E. Witko
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Wyeth LLC
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Wyeth LLC
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Publication of AU2008343919A1 publication Critical patent/AU2008343919A1/en
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Publication of AU2008343919B2 publication Critical patent/AU2008343919B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20251—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20251—Methods of production or purification of viral material
    • C12N2760/20252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2008343919A 2007-12-20 2008-12-18 Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein Ceased AU2008343919B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1535307P 2007-12-20 2007-12-20
US61/015,353 2007-12-20
PCT/US2008/013817 WO2009085172A1 (en) 2007-12-20 2008-12-18 Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein

Publications (2)

Publication Number Publication Date
AU2008343919A1 AU2008343919A1 (en) 2009-07-09
AU2008343919B2 true AU2008343919B2 (en) 2013-01-17

Family

ID=40418917

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008343919A Ceased AU2008343919B2 (en) 2007-12-20 2008-12-18 Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein

Country Status (8)

Country Link
US (1) US20090162321A1 (enExample)
EP (1) EP2225264A1 (enExample)
JP (1) JP2011507514A (enExample)
AR (1) AR069885A1 (enExample)
AU (1) AU2008343919B2 (enExample)
CA (1) CA2710166A1 (enExample)
CL (1) CL2008003821A1 (enExample)
WO (1) WO2009085172A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101723900B1 (ko) 2009-06-08 2017-04-07 더 유니버시티 오브 웨스트 온타리오 면역화 요법용 발현 벡터로서의 수포성 구내염 바이러스의 상이한 혈청형
US9610346B2 (en) 2012-03-23 2017-04-04 International Aids Vaccine Initiative Recombinant viral vectors
EP3681523A4 (en) * 2017-09-15 2021-12-29 The Ohio State Innovation Foundation Vaccines and methods of making and using vaccines for prevention of respiratory syncytial virus (rsv) infections
US12467050B2 (en) * 2017-10-02 2025-11-11 Georgia Tech Research Corporation Methods and compositions for engineering synthetic bioswitches for remote control of biological activity
CN109750006A (zh) * 2019-01-14 2019-05-14 青岛农业大学 一种犬瘟热病毒复制缺陷毒株及其构建方法
CN112430582B (zh) * 2020-12-04 2022-05-03 北京艺妙神州医药科技有限公司 一种慢病毒稳定包装细胞系及其制备方法
CN115725657B (zh) * 2022-09-16 2024-06-04 中国科学院广州生物医药与健康研究院 一种节段化的水泡性口炎病毒载体及其制备方法和应用
CN117051040B (zh) * 2023-08-15 2024-10-01 北京百普赛斯生物科技股份有限公司 Vsv△g复制缺陷型病毒制备及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
CA2288434C (en) * 1997-05-02 2012-01-03 The Uab Research Foundation Attenuation of negative stranded rna viruses by rearrangement of their genes and uses thereof
US6596529B1 (en) * 1997-05-02 2003-07-22 Uab Research Foundation Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
AU2046801A (en) * 1999-11-23 2001-06-04 Mayo Foundation For Medical Education And Research Gene expression by positive feedback activation of a cell type-specific promoter
WO2004113517A2 (en) * 2003-06-09 2004-12-29 Wyeth IMPROVED METHOD FOR THE RECOVERY OF NON-SEGMENTED, NEGATIVE-STRANDED RNA VIRUSES FROM cDNA
US8008268B2 (en) * 2006-07-25 2011-08-30 Merial Limited Vaccines against vesicular stomatitis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Kahn et al (2001) J Virol, vol. 75, pps. 11079-11087 *
Roberts et al (1999) J Virol, vol. 73, pps 3723-3732 *
Ternette et al (2007) Virol J vol. 4, pps 51-60 *

Also Published As

Publication number Publication date
CL2008003821A1 (es) 2009-04-03
JP2011507514A (ja) 2011-03-10
WO2009085172A1 (en) 2009-07-09
US20090162321A1 (en) 2009-06-25
AU2008343919A1 (en) 2009-07-09
AR069885A1 (es) 2010-02-24
EP2225264A1 (en) 2010-09-08
CA2710166A1 (en) 2009-07-09

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired