AU2008343919B2 - Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein - Google Patents

Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein Download PDF

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Publication number
AU2008343919B2
AU2008343919B2 AU2008343919A AU2008343919A AU2008343919B2 AU 2008343919 B2 AU2008343919 B2 AU 2008343919B2 AU 2008343919 A AU2008343919 A AU 2008343919A AU 2008343919 A AU2008343919 A AU 2008343919A AU 2008343919 B2 AU2008343919 B2 AU 2008343919B2
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Australia
Prior art keywords
vsv
protein
cells
virus
cell
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Ceased
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AU2008343919A
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English (en)
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AU2008343919A1 (en
Inventor
Roger M. Hendry
J. Erik Johnson
Christopher L. Parks
Maninder K. Sidhu
Susan E. Witko
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Wyeth LLC
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Wyeth LLC
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20251Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20251Methods of production or purification of viral material
    • C12N2760/20252Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2008343919A 2007-12-20 2008-12-18 Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein Ceased AU2008343919B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1535307P 2007-12-20 2007-12-20
US61/015,353 2007-12-20
PCT/US2008/013817 WO2009085172A1 (en) 2007-12-20 2008-12-18 Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein

Publications (2)

Publication Number Publication Date
AU2008343919A1 AU2008343919A1 (en) 2009-07-09
AU2008343919B2 true AU2008343919B2 (en) 2013-01-17

Family

ID=40418917

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008343919A Ceased AU2008343919B2 (en) 2007-12-20 2008-12-18 Methods for packaging propagation-defective Vesicular Stomatitis Virus vectors using a stable cell line that expresses G protein

Country Status (8)

Country Link
US (1) US20090162321A1 (enExample)
EP (1) EP2225264A1 (enExample)
JP (1) JP2011507514A (enExample)
AR (1) AR069885A1 (enExample)
AU (1) AU2008343919B2 (enExample)
CA (1) CA2710166A1 (enExample)
CL (1) CL2008003821A1 (enExample)
WO (1) WO2009085172A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9248178B2 (en) 2009-06-08 2016-02-02 Chil-Yong Kang Different serotypes of vesicular stomatitis virus as expression vectors for immunization regimens
US9610346B2 (en) 2012-03-23 2017-04-04 International Aids Vaccine Initiative Recombinant viral vectors
WO2019055768A1 (en) * 2017-09-15 2019-03-21 Ohio State Innovation Foundation VACCINES AND METHODS OF MAKING AND USING VACCINES FOR THE PREVENTION OF SYNCYTIAL RESPIRATORY VIRUS (RSV) INFECTIONS
WO2019070704A1 (en) * 2017-10-02 2019-04-11 Georgia Tech Research Corporation METHODS AND COMPOSITIONS FOR ENGINEERING SYNTHESIS BIOLOGICAL SWITCHES FOR REMOTE CONTROL OF BIOLOGICAL ACTIVITY
CN109750006A (zh) * 2019-01-14 2019-05-14 青岛农业大学 一种犬瘟热病毒复制缺陷毒株及其构建方法
CN112430582B (zh) * 2020-12-04 2022-05-03 北京艺妙神州医药科技有限公司 一种慢病毒稳定包装细胞系及其制备方法
CN115725657B (zh) * 2022-09-16 2024-06-04 中国科学院广州生物医药与健康研究院 一种节段化的水泡性口炎病毒载体及其制备方法和应用
CN117051040B (zh) * 2023-08-15 2024-10-01 北京百普赛斯生物科技股份有限公司 Vsv△g复制缺陷型病毒制备及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US6596529B1 (en) * 1997-05-02 2003-07-22 Uab Research Foundation Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
US6136585A (en) * 1997-05-02 2000-10-24 Uab Research Foundation Attenuation of negative stranded RNA viruses by rearrangement of genes and uses thereof
AU2046801A (en) * 1999-11-23 2001-06-04 Mayo Foundation For Medical Education And Research Gene expression by positive feedback activation of a cell type-specific promoter
KR100999316B1 (ko) * 2003-06-09 2010-12-10 와이어쓰 엘엘씨 cDNA로부터의 비분절 네가티브 쇄 RNA 바이러스의회수를 위한 개선된 방법
US8008268B2 (en) * 2006-07-25 2011-08-30 Merial Limited Vaccines against vesicular stomatitis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Kahn et al (2001) J Virol, vol. 75, pps. 11079-11087 *
Roberts et al (1999) J Virol, vol. 73, pps 3723-3732 *
Ternette et al (2007) Virol J vol. 4, pps 51-60 *

Also Published As

Publication number Publication date
AU2008343919A1 (en) 2009-07-09
CL2008003821A1 (es) 2009-04-03
WO2009085172A1 (en) 2009-07-09
US20090162321A1 (en) 2009-06-25
EP2225264A1 (en) 2010-09-08
AR069885A1 (es) 2010-02-24
JP2011507514A (ja) 2011-03-10
CA2710166A1 (en) 2009-07-09

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired