AU2008322437B2 - Use of nitrite salts in chronic ischemia - Google Patents
Use of nitrite salts in chronic ischemia Download PDFInfo
- Publication number
- AU2008322437B2 AU2008322437B2 AU2008322437A AU2008322437A AU2008322437B2 AU 2008322437 B2 AU2008322437 B2 AU 2008322437B2 AU 2008322437 A AU2008322437 A AU 2008322437A AU 2008322437 A AU2008322437 A AU 2008322437A AU 2008322437 B2 AU2008322437 B2 AU 2008322437B2
- Authority
- AU
- Australia
- Prior art keywords
- tissue
- nitrite
- ischemic
- chronic
- ischemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US315007P | 2007-11-15 | 2007-11-15 | |
| US61/003,150 | 2007-11-15 | ||
| PCT/US2008/083830 WO2009065142A2 (en) | 2007-11-15 | 2008-11-17 | Use of nitrite salts in chronic ischemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008322437A1 AU2008322437A1 (en) | 2009-05-22 |
| AU2008322437B2 true AU2008322437B2 (en) | 2013-11-07 |
Family
ID=40639493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008322437A Ceased AU2008322437B2 (en) | 2007-11-15 | 2008-11-17 | Use of nitrite salts in chronic ischemia |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9649334B2 (https=) |
| EP (1) | EP2219657A4 (https=) |
| JP (2) | JP5795165B2 (https=) |
| CN (1) | CN101939014B (https=) |
| AU (1) | AU2008322437B2 (https=) |
| IL (1) | IL205720A (https=) |
| WO (1) | WO2009065142A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2219657A4 (en) | 2007-11-15 | 2020-01-08 | Louisiana State University | USE OF NITRITE SALTS IN CHRONIC ISCHEMIA |
| US8568793B2 (en) * | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| US20120237617A1 (en) * | 2009-06-18 | 2012-09-20 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| CA2777066C (en) | 2009-10-14 | 2020-02-18 | TheraVasc, LLC | Pharmaceutical formulations of nitrite and uses thereof |
| US20130209584A1 (en) * | 2009-10-14 | 2013-08-15 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| CA2899602C (en) | 2013-02-20 | 2024-01-30 | Theravasc Inc. | Pharmaceutical uses of inorganic nitrites |
| US10517817B2 (en) | 2013-05-09 | 2019-12-31 | Syk Technologies, Llc | Deep topical systemic nitric oxide therapy apparatus and method |
| WO2017132275A1 (en) | 2016-01-27 | 2017-08-03 | Syk Technologies, Llc | Nitric oxide topical application apparatus and methods |
| TWI698241B (zh) | 2017-09-05 | 2020-07-11 | 國立成功大學 | 用於治療缺血的肝素組合物 |
| WO2020141546A1 (en) | 2019-01-02 | 2020-07-09 | Celagenex Research (India) Pvt. Ltd. | Synergistic nutritional compositions for pain management |
| US12459820B2 (en) | 2020-06-11 | 2025-11-04 | J. W. Randolph Miller | Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060182815A1 (en) * | 2004-07-09 | 2006-08-17 | Use of nitrite salts for the treatment of cardiovascular conditions |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914446A (en) | 1958-06-26 | 1959-11-24 | Upjohn Co | Nitrite stabilized ascorbic acid-cyanocobalamin compositions |
| US4650484A (en) | 1983-02-03 | 1987-03-17 | Alza Corporation | Method for treating ischemic conditions |
| IE64726B1 (en) | 1987-11-20 | 1995-08-23 | Elan Corp Plc | Pharmaceutical formulations for preventing drug tolerance |
| US5122384A (en) | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
| US5278192A (en) | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
| US6709681B2 (en) | 1995-02-17 | 2004-03-23 | Aberdeen University | Acidified nitrite as an antimicrobial agent |
| US20110196039A9 (en) | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
| US5648101A (en) * | 1994-11-14 | 1997-07-15 | Tawashi; Rashad | Drug delivery of nitric oxide |
| US5770645A (en) | 1996-08-02 | 1998-06-23 | Duke University Medical Center | Polymers for delivering nitric oxide in vivo |
| US5994444A (en) | 1997-10-16 | 1999-11-30 | Medtronic, Inc. | Polymeric material that releases nitric oxide |
| US7371415B1 (en) | 1998-04-03 | 2008-05-13 | The Daily Wellness Company | Method and composition for improving sexual fitness |
| US7015876B1 (en) | 1998-06-03 | 2006-03-21 | Lear Corporation | Heads-up display with improved contrast |
| US6103275A (en) * | 1998-06-10 | 2000-08-15 | Nitric Oxide Solutions | Systems and methods for topical treatment with nitric oxide |
| WO2000003725A1 (en) | 1998-07-14 | 2000-01-27 | Paracelsian, Inc. | Method for identifying and confirming consistent bio-functionality of natural compositions |
| US6962717B1 (en) | 1999-01-29 | 2005-11-08 | Disphar International B.V. | Pharmaceutical compositions |
| GB9905425D0 (en) | 1999-03-09 | 1999-05-05 | Queen Mary & Westfield College | Pharmaceutical composition |
| US6314956B1 (en) | 1999-09-08 | 2001-11-13 | Duke University | Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders |
| CN1299690C (zh) * | 2000-07-28 | 2007-02-14 | 生物能量公司 | 用于提高心血管功能的组合物 |
| GB0119011D0 (en) | 2001-08-03 | 2001-09-26 | Univ Aberdeen | Treatment of nail infections |
| EP1492509A1 (en) | 2001-12-18 | 2005-01-05 | ALZA Corporation | Dosage form providing time-varying patterns of drug delivery |
| EP1336602A1 (en) | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
| CA2379211A1 (fr) | 2002-03-28 | 2003-09-28 | Institut De Cardiologie De Montreal | Utilisation du bleu de methylene pour renverser la reaction hemodynamique exageree induite par la combinaison d'un derive nitre et du sildenafil ou d'une molecule de meme classe (inhibiteur de la phosphodiesterase) |
| ES2294543T3 (es) | 2003-07-09 | 2008-04-01 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal | Uso de sales de nitrilo para el tratamiento de afecciones cardiovasculares. |
| JP2007502831A (ja) | 2003-08-20 | 2007-02-15 | ニトロメッド インコーポレーティッド | ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法 |
| WO2005023189A2 (en) * | 2003-09-03 | 2005-03-17 | Pharmacia Corporation | Method of cox-2 selective inhibitor and nitric oxide-donating agent |
| US20060083824A1 (en) | 2004-10-20 | 2006-04-20 | Pbm Products Llc | Nutritional supplements for glucose intolerant individuals |
| AU2006249771A1 (en) | 2005-05-24 | 2006-11-30 | Wellgen, Inc. | Compositions and methods for the prevention and treatment of conditions associated with inflammation |
| WO2007094827A2 (en) | 2006-02-10 | 2007-08-23 | Mannatech, Inc. | All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization |
| GB0607402D0 (en) * | 2006-04-12 | 2006-05-24 | Barts & London Nhs Trust | Therapeutic composition and use |
| US8333997B2 (en) * | 2006-06-21 | 2012-12-18 | Albert Einstein College Of Medicine Of Yeshiva University | Compositions for sustained release of nitric oxide, methods of preparing same and uses thereof |
| DK2124638T3 (en) | 2007-02-26 | 2017-03-20 | Heartbeet Ltd | COMPOSITION INCREASING PERFORMANCE AND USING IT |
| CA2678097C (en) * | 2007-02-26 | 2023-03-14 | Jon Lundberg | New use of nitrites and nitrates and compositions containing these |
| WO2008153762A2 (en) | 2007-05-25 | 2008-12-18 | N30 Pharmaceuticals, Llc | S-nitrosothiol formulations and storage systems |
| EP2219657A4 (en) | 2007-11-15 | 2020-01-08 | Louisiana State University | USE OF NITRITE SALTS IN CHRONIC ISCHEMIA |
| WO2009086470A2 (en) | 2007-12-27 | 2009-07-09 | Aires Pharmaceuticals, Inc. | Aerosolized nitrite and nitric oxide - donating compounds and uses thereof |
| WO2010036236A1 (en) | 2008-09-23 | 2010-04-01 | Baker Hughes Incorporated | Anchor assembly |
| US8568793B2 (en) | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| US20120237617A1 (en) | 2009-06-18 | 2012-09-20 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| CA2777066C (en) | 2009-10-14 | 2020-02-18 | TheraVasc, LLC | Pharmaceutical formulations of nitrite and uses thereof |
| US20130209584A1 (en) | 2009-10-14 | 2013-08-15 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| WO2012135623A1 (en) | 2011-03-31 | 2012-10-04 | Theravasc Inc. | Use of nitrites for the treatment of cerebral amyloid angiopathy, age associated dementia, and cognitive decline |
| US20140112983A1 (en) | 2011-04-14 | 2014-04-24 | Theravasc Inc. | Nitrite compositions and uses thereof |
| US9294956B2 (en) | 2011-12-29 | 2016-03-22 | Qualcomm Incorporated | Application-server-assisted preemptive multicast bearer establishment for real-time low-latency applications |
| CA2899602C (en) * | 2013-02-20 | 2024-01-30 | Theravasc Inc. | Pharmaceutical uses of inorganic nitrites |
-
2008
- 2008-11-17 EP EP08849380.4A patent/EP2219657A4/en not_active Withdrawn
- 2008-11-17 US US12/741,436 patent/US9649334B2/en active Active
- 2008-11-17 JP JP2010534267A patent/JP5795165B2/ja active Active
- 2008-11-17 AU AU2008322437A patent/AU2008322437B2/en not_active Ceased
- 2008-11-17 WO PCT/US2008/083830 patent/WO2009065142A2/en not_active Ceased
- 2008-11-17 CN CN200880116483.4A patent/CN101939014B/zh not_active Expired - Fee Related
-
2010
- 2010-05-12 IL IL205720A patent/IL205720A/en active IP Right Grant
-
2014
- 2014-05-08 JP JP2014097072A patent/JP5908527B2/ja not_active Expired - Fee Related
-
2017
- 2017-04-10 US US15/483,187 patent/US10864229B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060182815A1 (en) * | 2004-07-09 | 2006-08-17 | Use of nitrite salts for the treatment of cardiovascular conditions |
Non-Patent Citations (1)
| Title |
|---|
| Jung, KH et al (2006) Stroke. Volume 37. Pages 27442750 * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL205720A0 (en) | 2010-11-30 |
| US9649334B2 (en) | 2017-05-16 |
| US10864229B2 (en) | 2020-12-15 |
| JP5795165B2 (ja) | 2015-10-14 |
| JP5908527B2 (ja) | 2016-04-26 |
| CN101939014A (zh) | 2011-01-05 |
| WO2009065142A2 (en) | 2009-05-22 |
| CN101939014B (zh) | 2016-04-27 |
| EP2219657A2 (en) | 2010-08-25 |
| IL205720A (en) | 2015-08-31 |
| EP2219657A4 (en) | 2020-01-08 |
| US20110311653A1 (en) | 2011-12-22 |
| JP2011503212A (ja) | 2011-01-27 |
| JP2014139255A (ja) | 2014-07-31 |
| US20170312310A1 (en) | 2017-11-02 |
| AU2008322437A1 (en) | 2009-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |