AU2008267274A1 - Sildenafil N-oxide as prodrug - Google Patents

Sildenafil N-oxide as prodrug Download PDF

Info

Publication number
AU2008267274A1
AU2008267274A1 AU2008267274A AU2008267274A AU2008267274A1 AU 2008267274 A1 AU2008267274 A1 AU 2008267274A1 AU 2008267274 A AU2008267274 A AU 2008267274A AU 2008267274 A AU2008267274 A AU 2008267274A AU 2008267274 A1 AU2008267274 A1 AU 2008267274A1
Authority
AU
Australia
Prior art keywords
sildenafil
oxide
compound
treating
erectile dysfunction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008267274A
Other languages
English (en)
Inventor
Cornelis G. Kruse
Axel Stoit
Martinus Tulp
Lechoslaw A. Turski
Sander Vader
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Healthcare Products BV
Original Assignee
Solvay Pharmaceuticals BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals BV filed Critical Solvay Pharmaceuticals BV
Publication of AU2008267274A1 publication Critical patent/AU2008267274A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2008267274A 2007-06-26 2008-06-23 Sildenafil N-oxide as prodrug Abandoned AU2008267274A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US94619807P 2007-06-26 2007-06-26
EP07111030.8 2007-06-26
US60/946,198 2007-06-26
EP07111030 2007-06-26
PCT/EP2008/057940 WO2009000798A1 (en) 2007-06-26 2008-06-23 Sildenafil n-oxide as prodrug

Publications (1)

Publication Number Publication Date
AU2008267274A1 true AU2008267274A1 (en) 2008-12-31

Family

ID=39758764

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008267274A Abandoned AU2008267274A1 (en) 2007-06-26 2008-06-23 Sildenafil N-oxide as prodrug

Country Status (7)

Country Link
EP (1) EP2170895A1 (de)
KR (1) KR20100050488A (de)
AU (1) AU2008267274A1 (de)
CA (1) CA2690294A1 (de)
EA (1) EA201070056A1 (de)
IL (1) IL202465A0 (de)
WO (1) WO2009000798A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010006227A (es) 2010-06-07 2011-12-14 World Trade Imp Exp Wtie Ag Nuevos derivados 1,4-diazepanos, inhibidores de pde-5.
AT512084A1 (de) 2011-10-20 2013-05-15 Univ Wien Tech Diazabicyclo- und diazaspiro-alkanderivate als phosphodiesterase-5 inhibitoren

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU734734B2 (en) * 1997-10-28 2001-06-21 Vivus, Inc. Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
CA2475377A1 (en) * 2002-02-07 2003-08-14 Pfizer Inc. Use of pde5 inhibitors such as sildenafil in the treatment of polycystic ovary syndrome

Also Published As

Publication number Publication date
KR20100050488A (ko) 2010-05-13
EP2170895A1 (de) 2010-04-07
IL202465A0 (en) 2010-06-30
WO2009000798A1 (en) 2008-12-31
EA201070056A1 (ru) 2010-06-30
CA2690294A1 (en) 2008-12-31

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period