AU2008253505B2 - Mutant reoviruses and methods of making and using - Google Patents
Mutant reoviruses and methods of making and using Download PDFInfo
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- AU2008253505B2 AU2008253505B2 AU2008253505A AU2008253505A AU2008253505B2 AU 2008253505 B2 AU2008253505 B2 AU 2008253505B2 AU 2008253505 A AU2008253505 A AU 2008253505A AU 2008253505 A AU2008253505 A AU 2008253505A AU 2008253505 B2 AU2008253505 B2 AU 2008253505B2
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2720/00011—Details
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- C12N2720/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Applications Claiming Priority (3)
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| US93925507P | 2007-05-21 | 2007-05-21 | |
| US60/939,255 | 2007-05-21 | ||
| PCT/CA2008/000964 WO2008141448A1 (en) | 2007-05-21 | 2008-05-21 | Mutant reoviruses and methods of making and using |
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| AU2008253505A1 AU2008253505A1 (en) | 2008-11-27 |
| AU2008253505B2 true AU2008253505B2 (en) | 2014-09-04 |
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| EP (1) | EP2150613B1 (enExample) |
| JP (1) | JP2010527593A (enExample) |
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| AR (1) | AR066649A1 (enExample) |
| AU (1) | AU2008253505B2 (enExample) |
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| GB0720624D0 (en) * | 2007-10-20 | 2007-11-28 | Academisch Ziekenhuis Leiden | Viral Modification |
| JP2011500608A (ja) * | 2007-10-22 | 2011-01-06 | オンコリティクス バイオテク，インコーポレーテッド | 増殖性障害の治療レジメン |
| MX339014B (es) * | 2008-05-27 | 2016-05-09 | Oncolytics Biotech Inc | Modulacion de presion intersticial y suministro y distribucion viral oncolitica. |
| CA2723587C (en) * | 2008-05-27 | 2017-09-26 | Oncolytics Biotech Inc. | Abrogating proinflammatory cytokine production during oncolytic reovirus therapy |
| ES2630012T3 (es) | 2010-12-02 | 2017-08-17 | Oncolytics Biotech Inc. | Formulaciones virales liofilizadas |
| EA201390810A1 (ru) | 2010-12-02 | 2013-09-30 | Онколитикс Байотек Инк. | Жидкие вирусные составы |
| EP3068411B1 (en) | 2013-11-15 | 2020-03-18 | Oncolytics Biotech Inc. | Oncolytic viruses and increased cancer treatment regimens |
| AU2017221592A1 (en) | 2016-02-16 | 2018-10-04 | Osaka University | Pharmaceutical composition for use in treating fibrosis |
| KR20210098202A (ko) * | 2020-01-31 | 2021-08-10 | 바이로큐어 주식회사 | 레오바이러스를 유효성분으로 포함하는 대장염의 예방 또는 치료용 조성물 |
| KR20220090467A (ko) * | 2020-12-22 | 2022-06-29 | 바이로큐어 주식회사 | 신규한 변형 레오바이러스 및 이의 용도 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2005111200A1 (en) * | 2004-05-17 | 2005-11-24 | Universite De Montreal | Novel strains of reoviruses and methods of uses thereof |
| WO2007099401A2 (en) * | 2005-08-01 | 2007-09-07 | University Technologies International, Inc. | Oncolytic attenuated reoviruses for treatment of proliferative disorders |
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| US4554101A (en) * | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US5023252A (en) * | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
| US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
| US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
| DE69937999T2 (de) * | 1998-06-12 | 2009-01-29 | Avir Green Hills Biotechnology Research Development Trade Ag | Interferon induzierende genetisch veränderte attenuierte viren |
| TWI289158B (en) * | 2000-08-10 | 2007-11-01 | Oncolytics Biotech Inc | Method of producing infectious reovirus |
| CA2428206C (en) * | 2000-11-09 | 2005-09-27 | Oncolytics Biotech Inc. | Methods for the treatment of cellular proliferative disorders |
| JP4087712B2 (ja) * | 2001-03-16 | 2008-05-21 | オンコリティクス バイオテック， インコーポレイティッド | 細胞培養物からウイルスを抽出する方法 |
| US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005111200A1 (en) * | 2004-05-17 | 2005-11-24 | Universite De Montreal | Novel strains of reoviruses and methods of uses thereof |
| WO2007099401A2 (en) * | 2005-08-01 | 2007-09-07 | University Technologies International, Inc. | Oncolytic attenuated reoviruses for treatment of proliferative disorders |
Non-Patent Citations (5)
| Title |
|---|
| AHMED, R. et al. Journal of Virology 1980, Vol. 34, pages 285- 287 * |
| CLARK, K.M. et al. Journal of Virology 2006, vol. 2006, pages 671-681 * |
| EBERT, D.H. et al. Journal of Virology 2001, vol. 75, pages 3197-3206 * |
| SHING, M. et al. Virus Research 1996, vol. 46, pages 19-29 * |
| WETZEL, J.D. et al. Journal of Virology 1997, vol. 71, pages 1362-1369 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2150613B1 (en) | 2016-10-19 |
| US20080292594A1 (en) | 2008-11-27 |
| IL200690A0 (en) | 2011-08-01 |
| DK2150613T3 (en) | 2017-01-30 |
| CN104195115A (zh) | 2014-12-10 |
| HK1136006A1 (en) | 2010-06-18 |
| AU2008253505A1 (en) | 2008-11-27 |
| ZA200907017B (en) | 2010-12-29 |
| WO2008141448A1 (en) | 2008-11-27 |
| EP2150613A4 (en) | 2011-01-19 |
| TW200909581A (en) | 2009-03-01 |
| CA2680661C (en) | 2018-05-29 |
| CA2680661A1 (en) | 2008-11-27 |
| IL200690A (en) | 2014-02-27 |
| AR066649A1 (es) | 2009-09-02 |
| ES2611455T3 (es) | 2017-05-09 |
| EP2150613A1 (en) | 2010-02-10 |
| CN101679953A (zh) | 2010-03-24 |
| JP2010527593A (ja) | 2010-08-19 |
| MX2009012420A (es) | 2009-12-09 |
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