AU2008216499B2 - Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure - Google Patents
Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure Download PDFInfo
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- AU2008216499B2 AU2008216499B2 AU2008216499A AU2008216499A AU2008216499B2 AU 2008216499 B2 AU2008216499 B2 AU 2008216499B2 AU 2008216499 A AU2008216499 A AU 2008216499A AU 2008216499 A AU2008216499 A AU 2008216499A AU 2008216499 B2 AU2008216499 B2 AU 2008216499B2
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89018107P | 2007-02-15 | 2007-02-15 | |
| US60/890,181 | 2007-02-15 | ||
| PCT/US2008/053386 WO2008100809A1 (en) | 2007-02-15 | 2008-02-08 | Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008216499A1 AU2008216499A1 (en) | 2008-08-21 |
| AU2008216499B2 true AU2008216499B2 (en) | 2014-04-17 |
Family
ID=39511007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008216499A Ceased AU2008216499B2 (en) | 2007-02-15 | 2008-02-08 | Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8362054B2 (OSRAM) |
| EP (1) | EP2118094B1 (OSRAM) |
| JP (1) | JP5566696B2 (OSRAM) |
| KR (1) | KR20090109587A (OSRAM) |
| CN (1) | CN101657445B (OSRAM) |
| AU (1) | AU2008216499B2 (OSRAM) |
| BR (1) | BRPI0807600A2 (OSRAM) |
| CA (1) | CA2678191A1 (OSRAM) |
| ES (1) | ES2404169T3 (OSRAM) |
| MX (1) | MX2009008734A (OSRAM) |
| NZ (1) | NZ598945A (OSRAM) |
| WO (1) | WO2008100809A1 (OSRAM) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ585103A (en) * | 2007-10-23 | 2012-04-27 | Allergan Inc | Substituted lactams derivatives and their uses for glaucoma and ocullar hypertension |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060205800A1 (en) * | 2004-12-10 | 2006-09-14 | Yariv Donde | Therapeutic Compounds |
| WO2006098918A2 (en) * | 2005-03-10 | 2006-09-21 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004521954A (ja) * | 2001-07-16 | 2004-07-22 | エフ．ホフマン−ラ ロシュ アーゲー | Ｅｐ４受容体作用薬としてのプロスタグランジン類似体 |
| KR100437972B1 (ko) * | 2001-10-27 | 2004-07-02 | 한국과학기술연구원 | 피롤리디논 유도체, 이의 제조 방법 및 이를 포함하는제약 조성물 |
| CN1653046A (zh) * | 2002-03-05 | 2005-08-10 | 小野药品工业株式会社 | 8－氮杂前列腺素衍生化合物以及包含该化合物作为活性成分的药物 |
| US6573294B1 (en) * | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| US7419999B2 (en) * | 2002-06-10 | 2008-09-02 | Applied Research Systems Ars Holding N.V. | Gamma lactams as prostaglandin agonists and use thereof |
| AU2003275838A1 (en) * | 2002-10-25 | 2004-05-13 | Beunard, Jean-Luc | Pyrrolidin-2-on derivatives as ep4 receptor agonists |
| US20080249028A1 (en) | 2005-03-09 | 2008-10-09 | Roger Williams Hospital | Thyrotropin-Releasing Hormone Analogs and Method of Use |
| CA2645867A1 (en) | 2006-03-20 | 2007-09-27 | Allergan, Inc. | Substituted gamma lactams as prostaglandin ep2 agonists |
-
2008
- 2008-02-08 BR BRPI0807600-6A patent/BRPI0807600A2/pt not_active IP Right Cessation
- 2008-02-08 CA CA002678191A patent/CA2678191A1/en not_active Abandoned
- 2008-02-08 US US12/527,155 patent/US8362054B2/en not_active Expired - Fee Related
- 2008-02-08 MX MX2009008734A patent/MX2009008734A/es active IP Right Grant
- 2008-02-08 KR KR1020097018979A patent/KR20090109587A/ko not_active Ceased
- 2008-02-08 JP JP2009549670A patent/JP5566696B2/ja not_active Expired - Fee Related
- 2008-02-08 NZ NZ598945A patent/NZ598945A/xx not_active IP Right Cessation
- 2008-02-08 EP EP08729358.5A patent/EP2118094B1/en not_active Not-in-force
- 2008-02-08 ES ES08729358T patent/ES2404169T3/es active Active
- 2008-02-08 WO PCT/US2008/053386 patent/WO2008100809A1/en not_active Ceased
- 2008-02-08 CN CN2008800120472A patent/CN101657445B/zh not_active Expired - Fee Related
- 2008-02-08 AU AU2008216499A patent/AU2008216499B2/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060205800A1 (en) * | 2004-12-10 | 2006-09-14 | Yariv Donde | Therapeutic Compounds |
| WO2006098918A2 (en) * | 2005-03-10 | 2006-09-21 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
Also Published As
| Publication number | Publication date |
|---|---|
| US8362054B2 (en) | 2013-01-29 |
| AU2008216499A1 (en) | 2008-08-21 |
| JP5566696B2 (ja) | 2014-08-06 |
| EP2118094B1 (en) | 2013-04-17 |
| ES2404169T3 (es) | 2013-05-24 |
| US20100168189A1 (en) | 2010-07-01 |
| WO2008100809A1 (en) | 2008-08-21 |
| BRPI0807600A2 (pt) | 2014-07-22 |
| JP2010519208A (ja) | 2010-06-03 |
| CA2678191A1 (en) | 2008-08-21 |
| KR20090109587A (ko) | 2009-10-20 |
| NZ598945A (en) | 2013-08-30 |
| MX2009008734A (es) | 2009-08-25 |
| CN101657445A (zh) | 2010-02-24 |
| CN101657445B (zh) | 2013-06-05 |
| EP2118094A1 (en) | 2009-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |