AU2007284724B2 - For the identification, assessment, and treatment of patients with cancer therapy - Google Patents

For the identification, assessment, and treatment of patients with cancer therapy Download PDF

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Publication number
AU2007284724B2
AU2007284724B2 AU2007284724A AU2007284724A AU2007284724B2 AU 2007284724 B2 AU2007284724 B2 AU 2007284724B2 AU 2007284724 A AU2007284724 A AU 2007284724A AU 2007284724 A AU2007284724 A AU 2007284724A AU 2007284724 B2 AU2007284724 B2 AU 2007284724B2
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AU
Australia
Prior art keywords
markers
expression
patient
marker
predictive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007284724A
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English (en)
Other versions
AU2007284724A1 (en
Inventor
Barbara M. Bryant
Andrew I. Damokosh
George Mulligan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of AU2007284724A1 publication Critical patent/AU2007284724A1/en
Application granted granted Critical
Publication of AU2007284724B2 publication Critical patent/AU2007284724B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2007284724A 2006-08-10 2007-08-09 For the identification, assessment, and treatment of patients with cancer therapy Ceased AU2007284724B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83676406P 2006-08-10 2006-08-10
US60/836,764 2006-08-10
PCT/US2007/017716 WO2008021183A2 (en) 2006-08-10 2007-08-09 For the identification, assessment, and treatment of patients with cancer therapy

Publications (2)

Publication Number Publication Date
AU2007284724A1 AU2007284724A1 (en) 2008-02-21
AU2007284724B2 true AU2007284724B2 (en) 2014-03-13

Family

ID=39082605

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007284724A Ceased AU2007284724B2 (en) 2006-08-10 2007-08-09 For the identification, assessment, and treatment of patients with cancer therapy

Country Status (7)

Country Link
US (1) US9500656B2 (cg-RX-API-DMAC7.html)
EP (1) EP2046973A4 (cg-RX-API-DMAC7.html)
JP (1) JP5725711B2 (cg-RX-API-DMAC7.html)
AU (1) AU2007284724B2 (cg-RX-API-DMAC7.html)
CA (1) CA2660275A1 (cg-RX-API-DMAC7.html)
MX (1) MX2009001489A (cg-RX-API-DMAC7.html)
WO (1) WO2008021183A2 (cg-RX-API-DMAC7.html)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2279417B1 (en) * 2008-05-28 2016-07-20 Georgia Tech Research Corporation Metabolic biomarkers for ovarian cancer and methods of use thereof
WO2010019921A2 (en) * 2008-08-15 2010-02-18 The Regents Of The University Of California Biomarkers for diagnosis and treatment of chronic lymphocytic leukemia
US20120149647A1 (en) * 2009-03-17 2012-06-14 Brody Jonathan R Methods for Assessing the Efficacy of Gemcitabine or Ara-C Treatment of Cancer Using Human Antigen R Levels
US8637481B2 (en) * 2009-04-17 2014-01-28 University Health Network Sensitizing agents for cancer therapy, methods of use and methods for the identification thereof
US20100280987A1 (en) * 2009-04-18 2010-11-04 Andrey Loboda Methods and gene expression signature for assessing ras pathway activity
US7615353B1 (en) * 2009-07-06 2009-11-10 Aveo Pharmaceuticals, Inc. Tivozanib response prediction
EP2486154B1 (en) * 2009-10-08 2017-03-01 Wake Forest University Health Sciences Diagnostic and prognostic markers for cancer
WO2011085263A2 (en) 2010-01-11 2011-07-14 Genomic Health, Inc. Method to use gene expression to determine likelihood of clinical outcome of renal cancer
WO2012024612A1 (en) * 2010-08-20 2012-02-23 Pangea Biosciences, Inc. Cancer diagnostic and cancer therapeutic
WO2013023132A1 (en) 2011-08-10 2013-02-14 Wake Forest University Health Sciences Diagnostic and prognostic markers for cancer
DK2742356T3 (en) 2011-08-11 2016-05-23 Janssen Pharmaceutica Nv CANCER TREATMENT PREDICTORS
WO2013112881A1 (en) 2012-01-27 2013-08-01 Thomas Jefferson University Mct protein inhibitor-related prognostic and therapeutic methods
EP2966985B1 (en) * 2013-03-15 2018-09-19 Mayo Foundation for Medical Education and Research Identification and monitoring of monoclonal immunoglobulins by molecular mass
US10022372B2 (en) 2013-04-19 2018-07-17 Thomas Jefferson University Caveolin-1 related methods for treating glioblastoma with temozolomide
SG11201506987VA (en) 2013-05-30 2015-10-29 Genomic Health Inc Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer
US20150287143A1 (en) * 2014-04-03 2015-10-08 John Hancock Life Insurance Company (U.S.A.) System and method for managing underwriting using a risk order approach
BR112016023046A8 (pt) 2014-04-04 2021-05-11 Mayo Found Medical Education & Res kit compreendendo anticorpos e agentes redutores
WO2015176749A1 (en) * 2014-05-20 2015-11-26 Erasmus University Medical Center Rotterdam Method for the treatment of multiple myeloma
WO2016018978A1 (en) 2014-07-29 2016-02-04 Mayo Foundation For Medical Education And Research Quantifying monoclonal antibody therapeutics by lc-ms/ms
WO2017053932A1 (en) 2015-09-24 2017-03-30 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
KR101949286B1 (ko) * 2015-10-26 2019-02-18 주식회사 싸이퍼롬 암 환자의 유전체 염기서열 변이 정보와 생존 정보를 이용한 맞춤형 약물 선택 방법 및 시스템
EP3523647B1 (en) 2016-09-07 2024-06-26 Mayo Foundation for Medical Education and Research Identification and monitoring of cleaved immunoglobulins by molecular mass
AU2018258683A1 (en) * 2017-04-28 2019-12-19 University Of Southern California System and method for predicting survival time
EP3681907A4 (en) 2017-09-13 2021-07-07 Mayo Foundation for Medical Education and Research IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J-CHAINS
WO2019055634A1 (en) 2017-09-13 2019-03-21 Mayo Foundation For Medical Education And Research IDENTIFICATION AND MONITORING OF A MACROPHAGE APOPTOSIS INHIBITOR
CN110108878A (zh) * 2019-05-30 2019-08-09 四川大学华西医院 Eif2s1自身抗体检测试剂在制备肺癌筛查试剂盒中的用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004053066A2 (en) * 2002-12-06 2004-06-24 Millennium Pharmaceuticals, Inc. Methods for the identification, assessment, and treatment of patients with proteasome inhibition therapy

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05296999A (ja) * 1992-04-24 1993-11-12 Amano Pharmaceut Co Ltd グルココルチコイドの効果判定マーカーとしてのヒトリポコルチンｉ及びその定量法
JP2004248502A (ja) * 2000-10-05 2004-09-09 Takara Holdings Inc 癌悪性度の評価方法
CA2481485A1 (en) * 2002-04-04 2003-10-16 Ishihara Sangyo Kaisha, Ltd. Apparatus and method for analyzing data
US20040191782A1 (en) * 2003-03-31 2004-09-30 Yixin Wang Colorectal cancer prognostics
US7741035B2 (en) * 2004-05-21 2010-06-22 Board Of Trustees Of The University Of Arkansas Use of gene expression profiling to predict survival in cancer patient
EP1899486A4 (en) * 2005-06-08 2009-07-22 Millennium Pharm Inc METHOD FOR IDENTIFYING, ASSESSING AND TREATING PATIENTS IN CANCER THERAPY

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004053066A2 (en) * 2002-12-06 2004-06-24 Millennium Pharmaceuticals, Inc. Methods for the identification, assessment, and treatment of patients with proteasome inhibition therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ball, N. S. and King, P. H., Clinical Cancer Research, 1997, Vol. 3, pages 1859-1865 *

Also Published As

Publication number Publication date
US20080064055A1 (en) 2008-03-13
US9500656B2 (en) 2016-11-22
MX2009001489A (es) 2009-02-18
EP2046973A4 (en) 2010-04-07
WO2008021183A3 (en) 2009-04-02
WO2008021183A9 (en) 2008-07-24
JP5725711B2 (ja) 2015-05-27
CA2660275A1 (en) 2008-02-21
WO2008021183A2 (en) 2008-02-21
AU2007284724A1 (en) 2008-02-21
JP2010500565A (ja) 2010-01-07
EP2046973A2 (en) 2009-04-15

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired