AU2007214427B2 - Reagents and methods for cancer prognosis and pathological staging - Google Patents

Reagents and methods for cancer prognosis and pathological staging Download PDF

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Publication number
AU2007214427B2
AU2007214427B2 AU2007214427A AU2007214427A AU2007214427B2 AU 2007214427 B2 AU2007214427 B2 AU 2007214427B2 AU 2007214427 A AU2007214427 A AU 2007214427A AU 2007214427 A AU2007214427 A AU 2007214427A AU 2007214427 B2 AU2007214427 B2 AU 2007214427B2
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AU
Australia
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expression
phosphorylation
biological markers
egfr
tissue
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Ceased
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AU2007214427A
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AU2007214427A1 (en
Inventor
Gary Anthony Pestano
Linda Kay Samadzadeh
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Ventana Medical Systems Inc
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Ventana Medical Systems Inc
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Priority to AU2012200691A priority Critical patent/AU2012200691B2/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57419Specifically defined cancers of colon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2007214427A 2006-02-16 2007-02-16 Reagents and methods for cancer prognosis and pathological staging Ceased AU2007214427B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012200691A AU2012200691B2 (en) 2006-02-16 2012-02-06 Reagents and methods for cancer prognosis and pathological staging

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77456306P 2006-02-16 2006-02-16
US60/774,563 2006-02-16
PCT/US2007/062362 WO2007095644A2 (fr) 2006-02-16 2007-02-16 reactifs et procedes pour le pronostic et la stadification pathologique d'un cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012200691A Division AU2012200691B2 (en) 2006-02-16 2012-02-06 Reagents and methods for cancer prognosis and pathological staging

Publications (2)

Publication Number Publication Date
AU2007214427A1 AU2007214427A1 (en) 2007-08-23
AU2007214427B2 true AU2007214427B2 (en) 2011-11-10

Family

ID=38335516

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007214427A Ceased AU2007214427B2 (en) 2006-02-16 2007-02-16 Reagents and methods for cancer prognosis and pathological staging

Country Status (10)

Country Link
US (2) US20070207489A1 (fr)
EP (2) EP2290361A1 (fr)
JP (1) JP5143026B2 (fr)
CN (2) CN101384901A (fr)
AT (1) ATE483972T1 (fr)
AU (1) AU2007214427B2 (fr)
CA (1) CA2642542C (fr)
DE (1) DE602007009645D1 (fr)
ES (1) ES2354181T3 (fr)
WO (1) WO2007095644A2 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009537154A (ja) 2006-05-18 2009-10-29 モレキュラー プロファイリング インスティテュート, インコーポレイテッド 疾患状態に対する個別化された医学的介入を決定するためのシステムおよび方法
US8768629B2 (en) * 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
WO2010017822A1 (fr) 2008-08-15 2010-02-18 Visiopharm A/S Procédé et système de détermination d'une cible dans un échantillon biologique par analyse d'image
US9697582B2 (en) 2006-11-16 2017-07-04 Visiopharm A/S Methods for obtaining and analyzing images
ES2374686T3 (es) 2007-05-14 2012-02-21 Historx, Inc. Separación en compartimentos por caracterización de píxel usando agrupamiento de datos de imágenes.
US7907271B2 (en) 2007-06-15 2011-03-15 Historx, Inc. Method and system for standardizing microscope instruments
CA2604317C (fr) 2007-08-06 2017-02-28 Historx, Inc. Methodes et systeme permettant de valider des echantillons d'images pour dosages immunologiques quantitatifs
CA2596204C (fr) 2007-08-07 2019-02-26 Historx, Inc. Procede et systeme de determination de la dilution optimale d'un reactif
WO2009029810A1 (fr) 2007-08-31 2009-03-05 Historx, Inc. Sélection de temps d'exposition automatique pour un tissu d'imagerie
GB2467691A (en) 2008-09-05 2010-08-11 Aueon Inc Methods for stratifying and annotating cancer drug treatment options
CA2737116C (fr) 2008-09-16 2019-01-15 Historx, Inc. Quantification reproductible de l'expression de biomarqueurs
CA2743211A1 (fr) 2008-11-12 2010-05-20 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Procedes et systemes d'utilisation d'exosomes pour determiner des phenotypes
US20120003664A1 (en) * 2008-12-09 2012-01-05 Uffe Lovborg Method for evaluating pre-treatment
WO2010083252A2 (fr) 2009-01-14 2010-07-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Biomarqueurs basés sur des taux et méthodes d'utilisation associées
AU2011223789A1 (en) 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
KR20130043104A (ko) 2010-04-06 2013-04-29 카리스 라이프 사이언스 룩셈부르크 홀딩스 질병용 순환 생물학적 지표들
CN102939538A (zh) * 2010-05-07 2013-02-20 霍夫曼-拉罗奇有限公司 用于离体检测细胞的诊断方法
CN101876659B (zh) * 2010-06-29 2013-02-13 同济大学 用于检测肿瘤的量子点试剂盒
WO2012040387A1 (fr) 2010-09-24 2012-03-29 The Board Of Trustees Of The Leland Stanford Junior University Capture directe, amplification et séquençage d'adn cible à l'aide d'amorces immobilisées
US9410207B2 (en) 2011-12-30 2016-08-09 Abbott Molecular Inc. Method and compositions for detecting epidermal growth factor receptor variant forms in cancer cells
CA2937659C (fr) * 2014-01-28 2023-05-02 Quest Diagnostics Investments Incorporated Procede et compositions permettant de detecter une transition adenome-adenocarcinome dans un cancer
CN103882139B (zh) * 2014-04-04 2015-06-03 上海赛安生物医药科技有限公司 一种用于化疗方案选择的多重基因检测试剂盒
JP6960224B2 (ja) * 2015-01-22 2021-11-05 コニカミノルタ株式会社 生体物質定量方法、病理診断支援システム及びプログラム
CN107688092B (zh) * 2017-08-18 2020-05-19 国家纳米科学中心 一种用于癌症患者预后评估的方法
KR102655467B1 (ko) 2018-02-28 2024-04-08 니토 보세키 가부시기가이샤 고정화 세포 또는 ffpe 조직 절편으로부터 항원성을 증강한 세포핵을 탈리하는 방법 그리고 그것을 위한 항원 부활제 및 키트

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004000102A2 (fr) * 2002-06-19 2003-12-31 Abgenix, Inc. Procede servant a predire une reponse a une therapie dirigee vers le recepteur du facteur de croissance epidermique
WO2004044218A2 (fr) * 2002-11-05 2004-05-27 The Regents Of The University Of California Procedes, substances et materiel permettant d'examiner des voies associees a la progression de glioblastome

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
US6872817B1 (en) 1986-01-16 2005-03-29 The Regents Of The Univ. Of California Method of staining target interphase chromosomal DNA
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US6326148B1 (en) 1999-07-12 2001-12-04 The Regents Of The University Of California Detection of copy number changes in colon cancer
US6649359B2 (en) * 2000-06-01 2003-11-18 The Brigham & Women's Hospital, Inc. Diagnosis of endometrial precancers
BR0207290A (pt) * 2001-02-16 2005-06-07 Immunivest Corp Método para analisar um paciente quanto à presença de uma malignidade, célula maligna isolada das células cultivadas, vacina de tumor, molécula associada com diátese de tumor alterada, métodos para determinar alterações em moléculas associadas com diátese de tumor como um meio para predizer a eficácia da terapia, como um meio para analisar dosagem apropriada para terapia, como um meio para monitorar eficácia da terapia, como um meio para analisar progressão de câncer, para realizar uma biópsia de corpo inteiro em um paciente, e para identificar alterações em uma célula de tumor circulante relativamente a células presentes numa massa de tumor in situ, e, kit de teste para analisar uma amostra de paciente quanto à presença de uma célula maligna não-hematopoiética
US20030190602A1 (en) * 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
EP2280003B1 (fr) * 2002-07-15 2014-04-02 Symphony Evolution, Inc. Procédé pour la préparation de modulateurs de kinases de type récepteur
US20050164218A1 (en) * 2003-05-30 2005-07-28 David Agus Gene expression markers for response to EGFR inhibitor drugs
DE10345021A1 (de) * 2003-09-23 2005-05-04 Univ Potsdam Verfahren zur nichtinvasiven Früherkennung von Dickdarmkrebs und/oder Darmkrebsvorläuferzellen
EP1774044A4 (fr) * 2004-06-03 2009-06-10 Univ Johns Hopkins Méthodes de criblage de prolifération cellulaire ou de troubles néoplasiques
JP2008504809A (ja) * 2004-06-04 2008-02-21 ジェネンテック・インコーポレーテッド Egfr突然変異
AU2005294214A1 (en) * 2004-10-07 2006-04-20 Emory University Multifunctional nanoparticles conjugates and their use
US8546376B2 (en) * 2009-09-18 2013-10-01 Almac Discovery Limited Pharmaceutical compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004000102A2 (fr) * 2002-06-19 2003-12-31 Abgenix, Inc. Procede servant a predire une reponse a une therapie dirigee vers le recepteur du facteur de croissance epidermique
WO2004044218A2 (fr) * 2002-11-05 2004-05-27 The Regents Of The University Of California Procedes, substances et materiel permettant d'examiner des voies associees a la progression de glioblastome

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KOPP R ET AL: "CLINICAL IMPLICATIONS OF THE EGF RECEPTOR/LIGAND SYSTEM FOR TUMOR PROGRESSION AND SURVIVAL IN GASTROINTESTINAL CARCINOMAS" RECENT RESULTS IN CANCER RESEARCH, Vol. 162,2003, pages 115-132 *

Also Published As

Publication number Publication date
DE602007009645D1 (de) 2010-11-18
ES2354181T3 (es) 2011-03-10
AU2007214427A1 (en) 2007-08-23
EP1984735B1 (fr) 2010-10-06
JP5143026B2 (ja) 2013-02-13
WO2007095644A2 (fr) 2007-08-23
JP2009527740A (ja) 2009-07-30
WO2007095644A3 (fr) 2007-12-27
US20100184099A1 (en) 2010-07-22
CN101384901A (zh) 2009-03-11
US20070207489A1 (en) 2007-09-06
CN104749378A (zh) 2015-07-01
EP1984735A2 (fr) 2008-10-29
EP2290361A1 (fr) 2011-03-02
ATE483972T1 (de) 2010-10-15
CA2642542C (fr) 2012-09-25
CA2642542A1 (fr) 2007-08-23

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired